Results 51 to 60 of about 9,562 (182)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Protonation and ring closure of stereoisomeric alpha-substituted cinnamic acids in superacidic media studied by 13C NMR spectroscopy and computations [PDF]

, 1998
Five alpha-substituted cinnamic acids [(E)- and (Z)-2,3-diphenyl-, (E)- and (Z)-3-(2-methoxyphenyl)-2-phenyl- and (E)-2-(2-methoxyphenyl)-3-phenyl-propenoic acids] have been protonated in fluorosulfonic acid at -78 degrees C, Protonation of the ...
Burrichter, Arwed, Olah, George A., Prakash, Surya G.K, Pálinkó, István, Rasul, Golam, Török, Béla   +5 more
core   +1 more source

The temperature dependence of the retention index for n-alkyl esters of acetic, propionic, cyclohexanecarboxylic, benzoic and phenylacetic acid on DB-1 and DB-5 capillary columns [PDF]

Journal of the Serbian Chemical Society, 2006
The temperature dependence of the retention index was studied for n-alkyl esters of acetic, propionic, cyclohexanecarboxylic, benzoic and phenylacetic acid on DB-1 and DB-5 capillary columns.
DUSAN Z. MIJIN, DUSAN G. ANTONOVIC
doaj   +3 more sources

Clinical study on gut microbiota and metabolomic characteristics in septic patients

Zhongguo Linchuang Yixue
ObjectiveTo explore the dynamic changes of gut microbiota metabolites in septic patients following admission, as well as the correlations between these metabolites, the gut microbiota, and the prognosis of septic patients.
Xiangyu Long, Zhenju Song, Mian Shao
doaj   +1 more source

Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

PLoS ONE, 2011
During chronic kidney disease (CKD), there is a progressive accumulation of toxic solutes due to inadequate renal clearance. Here, the interaction between uremic toxins and two important efflux pumps, viz. multidrug resistance protein 4 (MRP4) and breast
Henricus A M Mutsaers, Lambertus P van den Heuvel, Lauke H J Ringens, Anita C A Dankers, Frans G M Russel, Jack F M Wetzels, Joost G Hoenderop, Rosalinde Masereeuw   +7 more
doaj   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, EarlyView.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

The Microbiome–Metabolome Response in the Colon of Piglets Under the Status of Weaning Stress

Frontiers in Microbiology, 2020
Weaning is stressful for piglets involving nutritional, physiological, and psychological challenges, leading to an increase in the secretion of cortisol, changes in gut microbiome and metabolites, whereas the underlying relationships remain unclear.
Xueyuan Jiang, Naisheng Lu, Haichao Zhao, Haichao Zhao, Hao Yuan, Dong Xia, Hulong Lei   +6 more
doaj   +1 more source

2-Methoxy-2-phenylacetic acid

Acta Crystallographica Section E Structure Reports Online, 2003
2-Methoxy-2-phenyl­acetic acid, C9H10O3, forms helical columns of single enantiomers linked by hydrogen bonding between the acidic proton of one mol­ecule and the methoxy O atom of a neighbouring mol­ecule, to give an overall racemic structure.
Jens Hartung, Kristina Špehar, Ingrid Svoboda, Hartmut Fuess   +3 more
openaire   +1 more source

Host‐Induced Silencing of Rhizoctonia Solani 5‐Enolpyruvylshikimate‐3‐Phosphate Synthase Impairs Its Virulence in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar, Apoorva Prasad, Akshita Goel, Vijay Kumar Sharma, Jagjeet Singh Lore, Arun Kumar   +5 more
wiley   +1 more source

Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]

, 2002
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Casey, Lorraine A., Galt, Ronald H. B., Hadfield, Peter S., Page, Michael I., Vilanova, Bartholomew   +4 more
core   +1 more source