Results 71 to 80 of about 9,562 (182)

Nutritional and Phytochemical Content of High-Protein Crops [PDF]

, 2016
The authors acknowledge support from the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS) via their strategic research and partnership programs.Peer ...
Cantlay, Louise, Duncan, Gary, Multari, Salvatore, Neacsu, Madalina, Russell, Wendy R., Scobbie, Lorraine, Stewart, Derek, Vaughan, Nicholas   +7 more
core   +2 more sources

Genetic Modification of mfsT Gene Stimulating the Putative Penicillin Production in Monascus ruber M7 and Exhibiting the Sensitivity towards Precursor Amino Acids of Penicillin Pathway

Microorganisms, 2019
: The biosynthesis of penicillin G (PG) is compartmentalized, which forces penicillin and its intermediates to cross the membrane barriers. Although many aspects around the penicillin intermediates traffic system remain unclosed, the transmembrane ...
Rabia Ramzan, Muhammad Safiullah Virk, Zafarullah Muhammad, Amani Mohedein Mohammed Ahmed, Xi Yuan, Fusheng Chen   +5 more
doaj   +1 more source

Development of the HTRF assay to evaluate the auxin‐induced binding between TIR1 and IAA7

New Phytologist, Volume 250, Issue 5, Page 3475-3485, June 2026.
Summary Auxin plays diverse roles in plant growth and development, including sensing environmental changes. Quantifying the interaction between auxin coreceptors provides the molecular basis for cells to sense and adapt to environmental cues. Although several assays are available, a more high‐throughput method is necessary to efficiently evaluate the ...
Jekson Robertlee, Shinya Hagihara
wiley   +1 more source

Production of a recombinant membrane protein in an Escherichia coli strain for the whole cell biosynthesis of phenylacetic acids

Biotechnology Reports, 2015
The styrene oxide isomerase (SOI) represents a membrane-bound enzyme of the microbial styrene degradation pathway and has been discussed as promising biocatalyst. It catalyzes the isomerization of styrene oxide to phenylacetaldehyde. In this study a styC
Michel Oelschlägel, Claudia Heiland, Michael Schlömann, Dirk Tischler   +3 more
doaj   +1 more source

Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga, Nilu Gone, Mariana Ortiz de Godoy, Gabriel Correa Verissimo, Giovanna de Jesus Agostinetto, Liam Urich, Nadine Krüger, Thales Kronenberger, Rafael Victorio Carvalho Guido, Anthony J. O’Donoghue, Stefan A. Laufer, Thanigaimalai Pillaiyar   +11 more
wiley   +1 more source

Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2

BMC Microbiology, 2009
Background Metabolically versatile soil bacteria Burkholderia cepacia complex (Bcc) have emerged as opportunistic pathogens, especially of cystic fibrosis (CF).
Hamlin Jason NR, Bloodworth Ruhi AM, Cardona Silvia T   +2 more
doaj   +1 more source

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator. [PDF]

, 2015
BackgroundAmyloid-β (Aβ) 42 has been implicated as the initiating molecule in the pathogenesis of Alzheimer's disease (AD); thus, therapeutic strategies that target Aβ42 are of great interest.
Akula, Rajender, Ba, Saritha, Ceballos-Diaz, Carolina, Felsenstein, Kevin M, Golde, Todd E, Hochhaus, Günther, Jung, Joo In, Koo, Edward H, Ladd, Thomas B, Park, Hyo-Jin, Price, Ashleigh R, Ran, Yong, Shapiro, Gideon, Smithson, Lisa A, Tang, Yufei   +14 more
core   +3 more sources

Synthesis and characterization of rare earth metal complexes with novel Schiff base

Тонкие химические технологии
Objectives. The work set out to synthesize Schiff base ligands containing a hydrazone moiety of (Z)-2-((E)-1-hydroxyethylidene)hydrazineylidene)-2-phenylacetic acid, as well as their praseodymium, samarium, europium, and gadolinium complexes, and to ...
G. G. Abbasova, A. A. Medjidov, R. H. Ismayilov, A. M. Pashajanov, P. A. Fatullayeva   +4 more
doaj   +1 more source

PREPARATION OF (CHLOROCARBONYL) PHENYLKETENB AND ITS CYCLOADDITION REACTION WITH BENZALDEHYDEV [PDF]

Journal of Sciences, Islamic Republic of Iran, 1995
Meldrum's acid, 2'5-diphenyl-1'3-dioxane-4'6-dione, was produced by [2+2] cycloadditions of the (chlorocarbony1)phenylketene with benzaldehyde. Acid hydrolysis of the meldrum's acid regenerated benzaldehyde and also yielded phenylacetic acid as the final
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