Results 101 to 110 of about 15,789 (137)
Some of the next articles are maybe not open access.
Determination of p-halogenated phenylalanines and phenylalanine in plasma
Analytical Biochemistry, 1971Abstract A method for the determination, either in combination or singularly, for phenylalanine or some p -halogenated phenylalanines in blood plasma is presented. A thin-layer chromatographic procedure was elaborated which separates the p -halogenated phenylalanines from phenylalanine by means of a cation-exchange resin.
openaire +3 more sources
Fluorescence of the fluorinated phenylalanines
Analytical Biochemistry, 1962Abstract Fluorinated phenylalanines are much more intensely fluorescent than phenylalanine or the corresponding chlorinated or brominated compounds. The p -derivative fluoreces with a quantum efficiency of 0.40. These compounds possess excitation maxima at about 268 mμ and fluoresce at about 292 mμ.
Gordon Guroff, Michael A. Chirigos
openaire +3 more sources
Adsorption chromatography of phenylalanine
Biotechnology and Bioengineering, 1989Utilisation de la resine Amberlite XAD-4 dans le but de retenir des acides amines aromatiques tels que la phenylalanine, a partir de l'hydrolyse acide de la caseine.
Ana Lúcia Coutinho Santos Neto +3 more
openaire +3 more sources
Phenylalanine Hydroxylase Activity
Archives of Pediatrics & Adolescent Medicine, 1983Sir .—In the article, "Diagnosis of Phenylalanine Hydroxylase Deficiency (Phenylketonuria)" (Journal1982;136:111-114), we are concerned by the recommendation of Berry and collegues that centers treating patients with phenylketonuria (PKU) should " . . .
David M. Danks, Richard G.H. Cotton
openaire +2 more sources
Phenylalanine hydroxylase deficiency
Genetics in Medicine, 2011Phenylalanine hydroxylase deficiency is an autosomal recessive disorder that results in intolerance to the dietary intake of the essential amino acid phenylalanine. It occurs in approximately 1:15,000 individuals. Deficiency of this enzyme produces a spectrum of disorders including classic phenylketonuria, mild phenylketonuria, and mild ...
Yannis Trakadis +2 more
openaire +3 more sources
Characterization of phenylalanine hydroxylase
Biochemistry, 1986Iron can be bound to phenylalanine hydroxylase (PAH) in two environments. The assignment of the electron paramagnetic resonance spectrum of PAH to two, overlapping high-spin ferric signals is confirmed by computer simulation. Both environments are shown to be populated in the crude enzyme.
L. M. Bloom +2 more
openaire +3 more sources
Inhibition of dihydroxyphenylalanine decarboxylase by derivatives of phenylalanine
Archives of Biochemistry and Biophysics, 1954Abstract A series of compounds, related chemically to phenylalanine, have been examined for their action on dopa decarboxylase of pig kidney and on bacterial tyrosine decarboxylase. Some of the compounds were found to inhibit these enzymes. The relation between degree of inhibition and chemical structure of the inhibitors has been discussed ...
openaire +3 more sources
Toxicology and Applied Pharmacology, 2000
Ochratoxin A (OTA) is a nephrotoxic, hepatotoxic, and teratogenic mycotoxin produced by storage molds on a variety of foodstuffs. Its chemical structure is composed of an isocumarin part linked to l-phenylalanine. Inhibition of phenylalanine hydroxylase and other enzymes that use phenylalanine as substrate is based on this structural homology.
Tihana Žanić-Grubišić +5 more
openaire +4 more sources
Ochratoxin A (OTA) is a nephrotoxic, hepatotoxic, and teratogenic mycotoxin produced by storage molds on a variety of foodstuffs. Its chemical structure is composed of an isocumarin part linked to l-phenylalanine. Inhibition of phenylalanine hydroxylase and other enzymes that use phenylalanine as substrate is based on this structural homology.
Tihana Žanić-Grubišić +5 more
openaire +4 more sources
Photophysics of phenylalanine analogues
Journal of Photochemistry and Photobiology A: Chemistry, 2001The photophysical properties (fluorescence quantum yields and lifetimes) of linear analogues of phenylalanine (Phe) [β-homophenylalanine (β-Hph), β-phenylalanine (β-Phe), phenyglycine (Phg)] in water at pH=6 and 1 have been measured. The obtained results indicate that relative space location of the amino, carboxyl groups and phenyl chromophore ...
Joanna Malicka +5 more
openaire +2 more sources
Phenylalanine deficiency syndrome
The Journal of Pediatrics, 1966Clinical observations are recorded on two infants in whom failure to gain, eczema and listlessness developed during severe dietary restriction of phenylalanine. Regular diet was resumed when they were found not to have phenylketonuria; in spite of improvement in their nutritional status, their developmental progress remained slow.
openaire +3 more sources