Results 281 to 290 of about 425,330 (380)

In Silico Design and Validation of a Novel HPPD‐Inhibiting Herbicide Candidate Based on Benzofuran and Arylthioacetic Acid Scaffolds

open access: yesChemistry &Biodiversity, EarlyView.
A benzofuran‐triketone hybrid emerged as the most promising 4‐hydroxyphenylpyruvate inhibitor, showing the highest predicted activity and strongest binding compared to the best experimental compound. Free computational tools guided candidate selection, predicted interactions with the enzyme, and confirmed stable binding.
Luiz R. Capucho   +2 more
wiley   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

open access: yesChemBioChem, EarlyView.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

A Robust Bioprocess for the Global Incorporation of Noncanonical Amino Acids in Auxotrophic Hosts Produces Labeled Proteins at the Gram Scale

open access: yesChemBioChem, EarlyView.
A robust bioprocess enables global incorporation of noncanonical amino acids in both shake flask and bioreactor cultures, producing gram‐per‐liter titers of efficiently labeled proteins. A versatile Escherichia coli BL21(DE3) auxotroph platform supports broad compatibility with various noncanonical amino acids and target proteins, facilitating flexible
Patrik Fladischer   +8 more
wiley   +1 more source

Tailoring PHA copolymer types via amino acid supplementation in dairy byproduct media. [PDF]

open access: yesSci Rep
Patil T   +7 more
europepmc   +1 more source

Intermediary Metabolism of Phenylalanine and Tyrosine in Diffuse Collagen Disease III

open access: bronze, 1957
Nagao Nishimura   +4 more
openalex   +2 more sources

Nutritional Content, Phytochemical Composition, and Physicochemical Properties of Different Quinoa (Chenopodium quinoa Willd.) Seed Varieties

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with documented benefits for human health. The macronutrient composition and phytochemical content of the grain are known to vary depending on the variety and the growing location.
Vassilios Raikos   +7 more
wiley   +1 more source

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