Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem+13 more
wiley +1 more source
Metabolite Profile and Metabolic Network Analysis of Walnuts (<i>Juglans regia</i> L.) in Response to Chilling Stress. [PDF]
Liu K+6 more
europepmc +1 more source
Studies on the locus of the enzyme recognition site in phenylalanine transfer RNA.
M.P. Stulberg, Kenneth R. Isham
openalex +1 more source
Fine‐Tuning Gramicidin S: How δ‐Phenylproline Affects Turns and Interaction with Membrane
Introducing a phenyl group at the 5‐cis position of proline in gramicidin S markedly alters its conformation. This substitution induces a double γ‐turn that disrupts the native β‐sheet and hinders membrane insertion. The incorporation of a phenyl ring at the 5‐position of proline markedly influences the conformation and membrane interactions of ...
Irene Sánchez‐Burillo+3 more
wiley +1 more source
Diffusivity alterations related to cognitive performance and phenylalanine levels in early-treated adults with phenylketonuria. [PDF]
Pardo J+8 more
europepmc +1 more source
Photoredox Decarboxylative 3‐Fluoroallylation of α‐Amino Acids
An efficient, photocatalytic method for the decarboxylative 3‐fluoroallylation of α‐amino acids has been developed to produce fluorinated homoallylamines. A broad reaction scope is reported, including the use of dipeptides and different protecting groups on nitrogen.
Taylor Semeniuk+5 more
wiley +1 more source
Identification of Metabolic Changes and Comparison of Antioxidant Activities in Two Pimpinella Species. [PDF]
Lim J+9 more
europepmc +1 more source
Infants with Tyrosinemia Type 1: Should phenylalanine be supplemented?
D. van Vliet+8 more
semanticscholar +1 more source
Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds
ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter+4 more
wiley +1 more source