Results 281 to 290 of about 390,444 (399)

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem   +13 more
wiley   +1 more source

Fine‐Tuning Gramicidin S: How δ‐Phenylproline Affects Turns and Interaction with Membrane

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Introducing a phenyl group at the 5‐cis position of proline in gramicidin S markedly alters its conformation. This substitution induces a double γ‐turn that disrupts the native β‐sheet and hinders membrane insertion. The incorporation of a phenyl ring at the 5‐position of proline markedly influences the conformation and membrane interactions of ...
Irene Sánchez‐Burillo   +3 more
wiley   +1 more source

Diffusivity alterations related to cognitive performance and phenylalanine levels in early-treated adults with phenylketonuria. [PDF]

open access: yesJ Neurodev Disord
Pardo J   +8 more
europepmc   +1 more source

Photoredox Decarboxylative 3‐Fluoroallylation of α‐Amino Acids

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
An efficient, photocatalytic method for the decarboxylative 3‐fluoroallylation of α‐amino acids has been developed to produce fluorinated homoallylamines. A broad reaction scope is reported, including the use of dipeptides and different protecting groups on nitrogen.
Taylor Semeniuk   +5 more
wiley   +1 more source

Identification of Metabolic Changes and Comparison of Antioxidant Activities in Two Pimpinella Species. [PDF]

open access: yesACS Omega
Lim J   +9 more
europepmc   +1 more source

Infants with Tyrosinemia Type 1: Should phenylalanine be supplemented?

open access: yesJIMD Reports, 2015
D. van Vliet   +8 more
semanticscholar   +1 more source

Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter   +4 more
wiley   +1 more source

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