Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases
GA: Genetically encoded internal electrophiles in ubiquitin (Ub) enable the profiling of multivalent interaction interfaces, addressing a key limitation of current Ub‐based activity‐based probes. In this study, these probes capture a Ub–deubiquitinase interaction with minimal structural perturbation and serve as selective diUb probes that covalently ...
Nipuni M. Pannala+7 more
wiley +1 more source
Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut microbiota. [PDF]
Wu L+6 more
europepmc +1 more source
A series of all‐cis ring fluorinated cyclohexylalanines with progressively increasing levels of vicinal fluorines, as well as 4‐fluorophenylalanine and pentafluoroarylphenylalanine were introduced into the WKYMVm peptide in place of its tyrosine residue, for assays against the G‐protein coupled formylpeptide receptor, FPR2.
David O'Hagan+6 more
wiley +1 more source
PHENYLALANINE METABOLISM IN DILUTE-LETHAL MICE
Harold Rauch, Martha T. Yost
openalex +2 more sources
ABSTRACT Background and Objectives Roller‐milling practices for pulses to establish potential end‐use applications are required. Scouring and moisture conditioning may improve milling efficiency and hull removal, in addition to influencing nutritional quality.
Adam J. Franczyk+10 more
wiley +1 more source
A Shortened Method for the Fluorometric Determination of Phenylalanine
John A. Ambrose
openalex +1 more source
Plasma-activated water modulates taxanes production and phenylalanineammonia-lyase activity in Taxus baccata cell culture. [PDF]
Fathali Tehrani MH+5 more
europepmc +1 more source
Solvent‐Enabled Selective Electrochemical Decarboxylative Acetoxylation of Fmoc‐Protected Peptides
Electrochemical decarboxylative acetoxylation of Fmoc‐protected peptides via anodic oxidation of the carboxylic acid is challenging under conventional conditions, due to the lability of the Fmoc protecting group. Using selected cosolvents which can be oxidized at higher potentials than the target carboxylic acid but lower than the protecting group, the
David M. Köpfler+8 more
wiley +1 more source
N-Lactoyl Amino Acids: Emerging Biomarkers in Metabolism and Disease. [PDF]
Naja K+4 more
europepmc +1 more source
Halogen Bond‐Tuning of Responsive Supramolecular Amino Acid Hydrogels
XB strongly influences both solid‐state packing and rheological properties of hydrogels of a tailored halogenated Fmoc‐amino acid in biomimetic environments. Interestingly, the addition of effective XB‐acceptors (Nu) to the gelation medium increased gel stiffness, preluding to the possible future development of XB‐responsive amino acid hydrogels in ...
Eleonora Veronese+6 more
wiley +1 more source