Results 301 to 310 of about 394,077 (382)

Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases

open access: yesChemBioChem, EarlyView.
GA: Genetically encoded internal electrophiles in ubiquitin (Ub) enable the profiling of multivalent interaction interfaces, addressing a key limitation of current Ub‐based activity‐based probes. In this study, these probes capture a Ub–deubiquitinase interaction with minimal structural perturbation and serve as selective diUb probes that covalently ...
Nipuni M. Pannala   +7 more
wiley   +1 more source

Bioactivity profiles of progressively ring‐fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto‐piperazines as anti‐trypanosome agents.

open access: yesChemBioChem, Accepted Article.
A series of all‐cis ring fluorinated cyclohexylalanines with progressively increasing levels of vicinal fluorines, as well as 4‐fluorophenylalanine and pentafluoroarylphenylalanine were introduced into the WKYMVm peptide in place of its tyrosine residue, for assays against the G‐protein coupled formylpeptide receptor, FPR2.
David O'Hagan   +6 more
wiley   +1 more source

The Assessment of In Vitro Protein Digestibility and Quality on Mechanically Scoured and Moisture Conditioned Navy Beans (Phaseolus vulgaris) and Chickpeas (Cicer arietinum) Subject to Roller‐Milling

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Roller‐milling practices for pulses to establish potential end‐use applications are required. Scouring and moisture conditioning may improve milling efficiency and hull removal, in addition to influencing nutritional quality.
Adam J. Franczyk   +10 more
wiley   +1 more source

Plasma-activated water modulates taxanes production and phenylalanineammonia-lyase activity in Taxus baccata cell culture. [PDF]

open access: yesPLoS One
Fathali Tehrani MH   +5 more
europepmc   +1 more source

Solvent‐Enabled Selective Electrochemical Decarboxylative Acetoxylation of Fmoc‐Protected Peptides

open access: yesChemElectroChem, EarlyView.
Electrochemical decarboxylative acetoxylation of Fmoc‐protected peptides via anodic oxidation of the carboxylic acid is challenging under conventional conditions, due to the lability of the Fmoc protecting group. Using selected cosolvents which can be oxidized at higher potentials than the target carboxylic acid but lower than the protecting group, the
David M. Köpfler   +8 more
wiley   +1 more source

N-Lactoyl Amino Acids: Emerging Biomarkers in Metabolism and Disease. [PDF]

open access: yesDiabetes Metab Res Rev
Naja K   +4 more
europepmc   +1 more source

Halogen Bond‐Tuning of Responsive Supramolecular Amino Acid Hydrogels

open access: yesChemistry – A European Journal, EarlyView.
XB strongly influences both solid‐state packing and rheological properties of hydrogels of a tailored halogenated Fmoc‐amino acid in biomimetic environments. Interestingly, the addition of effective XB‐acceptors (Nu) to the gelation medium increased gel stiffness, preluding to the possible future development of XB‐responsive amino acid hydrogels in ...
Eleonora Veronese   +6 more
wiley   +1 more source

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