Results 341 to 350 of about 394,077 (382)

Effect of dietary phenylalanine level on growth performance, body composition, and biochemical parameters in plasma of juvenile hybrid tilapia, Oreochromis niloticus × Oreochromis aureus

Journal of the World Aquaculture Society, 2020
An 8‐week feeding trial with juvenile hybrid tilapia (Oreochromis niloticus × Oreochromis aureus) was conducted to assess the effects of dietary phenylalanine on growth, body composition, and biochemical parameters in plasma.
Wei Xiao, Zhi‐Ying Zou, Dayu Li, Jinglin Zhu, Y. Yue, Hong Yang   +5 more
semanticscholar   +1 more source

Phenylalanine supplementation improves the phenylalanine profile in tyrosinaemia

Journal of Inherited Metabolic Disease, 2000
AbstractTyrosinaemia types I and II are caused by enzyme deficiencies in the tyrosine catabolism pathway. Successful treatment is possible with the novel enzyme inhibitor NTBC in tyrosinaemia type I and with dietary tyrosine and phenylalanine restriction in both conditions.
J. V. Leonard, K. G. Van Wyk, Peter E. Clayton, Callum Wilson   +3 more
openaire   +3 more sources

Isozymes of Phenylalanine Hydroxylase [PDF]

Science, 1972
Three isozymes of phenylalanine hydroxylase exist in adult rat liver. They are chromatographically unique. Partial characterization suggests that they are similar in chemical properties and differ only in charge. Estimation of the Stokes radii indicates that the isozymes have similar molecular weights of about 200,000. Two isozymes exist in human fetal
Paul J. Geiger, John A. Barranger, A. Huzino, Samuel P. Bessman   +3 more
openaire   +2 more sources

Effects of tetrahydrobiopterin and phenylalanine on in vivo human phenylalanine hydroxylase by phenylalanine breath test

Molecular Genetics and Metabolism, 2007
BH(4) administration results in the reduction of blood phenylalanine level in patients with tetrahydrobiopterin (BH(4))-responsive phenylalanine hydroxylase (PAH) deficiency. The mechanism underlying BH(4) response remains unknown. Here, we studied the effects of BH(4) and phenylalanine on in vivo PAH activity of normal controls using the phenylalanine
Tomoko Sakaguchi, Minoru Asada, Yoshiyuki Okano, Kazuhiko Takatori, Tsunekazu Yamano, Masahiro Kajiwara, Satoshi Kudo   +6 more
openaire   +3 more sources

Activation of phenylalanine hydroxylase by phenylalanine

Biochimica et Biophysica Acta (BBA) - Enzymology, 1971
Abstract 1. 1. Phenylalanine activates phenylalanine hydroxylase ( l -phenylalanine, tetrahydropteridine:oxygen oxidoreductase (4-hydroxylating), EC 1.14.3.1), when dithiothreitol is used to regenerate 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine. 2. 2.
openaire   +3 more sources

THE EFFECTS OF PHENYLALANINE ANALOGUES ON THE METABOLISM OF PHENYLALANINE IN RATS

Canadian Journal of Biochemistry, 1967
Rats expired14CO2slightly faster when DL-phenylalanine-1-14C rather than DL-phenylalanine-3-14C was injected. An injection of DL-fluorophenylalanine-3-14C produced more radioactive CO2than did phenylalanine-3-14C; DL-beta-thienylalanine-3-14C produced only trace amounts of14CO2but significant levels of radioactivity in the urine.
Gail Dolan, Claude Godin
openaire   +2 more sources

A SIMPLE PHENYLALANINE METHOD FOR DETECTING PHENYLKETONURIA IN LARGE POPULATIONS OF NEWBORN INFANTS.

Pediatrics, 1963
A new method is described for rapid and economical screening of large numbers of hospital nursery infants for elevation in blood phenylalanine associated with phenylketonuria. Results are presented for 682 infants, 96% of whom were 4 days of age. None of
R. Guthrie, Ada Susi
semanticscholar   +1 more source

The use of deuterated phenylalanine for the elucidation of the phenylalanine-tyrosine metabolism

Clinica Chimica Acta, 1972
Abstract The application in vivo of stable isotopes, e.g. deuterium, for the study of metabolic pathways is demonstrated on the example of the phenylalanine-tyrosine metabolism. A healthy child, a patient with phenylketonuria and a patient with hyper phenylalaninemia were loaded with 200 mg/kg of deuterated phenylalanine.
K. Baerlocher, J. A. Völlmin, H.-Ch. Curtius   +2 more
openaire   +3 more sources

Determination of p-halogenated phenylalanines and phenylalanine in plasma

Analytical Biochemistry, 1971
Abstract A method for the determination, either in combination or singularly, for phenylalanine or some p -halogenated phenylalanines in blood plasma is presented. A thin-layer chromatographic procedure was elaborated which separates the p -halogenated phenylalanines from phenylalanine by means of a cation-exchange resin.
openaire   +3 more sources

Synergistic Effect of a Thermal Reaction and Vacuum Dehydration on Improving Xylose-Phenylalanine Conversion to N-(1-Deoxy-d-xylulos-1-yl)-phenylalanine during an Aqueous Maillard Reaction.

Journal of Agricultural and Food Chemistry, 2018
The synergistic effect of a thermal reaction and vacuum dehydration on the conversion of xylose (Xyl) and phenylalanine (Phe) to a Maillard-reaction intermediate (MRI) was researched.
H. Cui, K. Hayat, C. Jia, E. Duhoranimana, Qingrong Huang, Xiaoming Zhang, Chi-Tang Ho   +6 more
semanticscholar   +1 more source