Results 351 to 360 of about 390,444 (399)
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A SIMPLE PHENYLALANINE METHOD FOR DETECTING PHENYLKETONURIA IN LARGE POPULATIONS OF NEWBORN INFANTS.
Pediatrics, 1963A new method is described for rapid and economical screening of large numbers of hospital nursery infants for elevation in blood phenylalanine associated with phenylketonuria. Results are presented for 682 infants, 96% of whom were 4 days of age. None of
R. Guthrie, Ada Susi
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THE EFFECTS OF PHENYLALANINE ANALOGUES ON THE METABOLISM OF PHENYLALANINE IN RATS
Canadian Journal of Biochemistry, 1967Rats expired14CO2slightly faster when DL-phenylalanine-1-14C rather than DL-phenylalanine-3-14C was injected. An injection of DL-fluorophenylalanine-3-14C produced more radioactive CO2than did phenylalanine-3-14C; DL-beta-thienylalanine-3-14C produced only trace amounts of14CO2but significant levels of radioactivity in the urine.
Gail Dolan, Claude Godin
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The use of deuterated phenylalanine for the elucidation of the phenylalanine-tyrosine metabolism
Clinica Chimica Acta, 1972Abstract The application in vivo of stable isotopes, e.g. deuterium, for the study of metabolic pathways is demonstrated on the example of the phenylalanine-tyrosine metabolism. A healthy child, a patient with phenylketonuria and a patient with hyper phenylalaninemia were loaded with 200 mg/kg of deuterated phenylalanine.
K. Baerlocher +2 more
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Determination of p-halogenated phenylalanines and phenylalanine in plasma
Analytical Biochemistry, 1971Abstract A method for the determination, either in combination or singularly, for phenylalanine or some p -halogenated phenylalanines in blood plasma is presented. A thin-layer chromatographic procedure was elaborated which separates the p -halogenated phenylalanines from phenylalanine by means of a cation-exchange resin.
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Fluorescence of the fluorinated phenylalanines
Analytical Biochemistry, 1962Abstract Fluorinated phenylalanines are much more intensely fluorescent than phenylalanine or the corresponding chlorinated or brominated compounds. The p -derivative fluoreces with a quantum efficiency of 0.40. These compounds possess excitation maxima at about 268 mμ and fluoresce at about 292 mμ.
Gordon Guroff, Michael A. Chirigos
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Journal of Agricultural and Food Chemistry, 2018
The synergistic effect of a thermal reaction and vacuum dehydration on the conversion of xylose (Xyl) and phenylalanine (Phe) to a Maillard-reaction intermediate (MRI) was researched.
H. Cui +6 more
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The synergistic effect of a thermal reaction and vacuum dehydration on the conversion of xylose (Xyl) and phenylalanine (Phe) to a Maillard-reaction intermediate (MRI) was researched.
H. Cui +6 more
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Phenylalanine Hydroxylase Activity
Archives of Pediatrics & Adolescent Medicine, 1983Sir .—In the article, "Diagnosis of Phenylalanine Hydroxylase Deficiency (Phenylketonuria)" (Journal1982;136:111-114), we are concerned by the recommendation of Berry and collegues that centers treating patients with phenylketonuria (PKU) should " . . .
David M. Danks, Richard G.H. Cotton
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Adsorption chromatography of phenylalanine
Biotechnology and Bioengineering, 1989Utilisation de la resine Amberlite XAD-4 dans le but de retenir des acides amines aromatiques tels que la phenylalanine, a partir de l'hydrolyse acide de la caseine.
Ana Lúcia Coutinho Santos Neto +3 more
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Phenylalanine hydroxylase deficiency
Genetics in Medicine, 2011Phenylalanine hydroxylase deficiency is an autosomal recessive disorder that results in intolerance to the dietary intake of the essential amino acid phenylalanine. It occurs in approximately 1:15,000 individuals. Deficiency of this enzyme produces a spectrum of disorders including classic phenylketonuria, mild phenylketonuria, and mild ...
Yannis Trakadis +2 more
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Characterization of phenylalanine hydroxylase
Biochemistry, 1986Iron can be bound to phenylalanine hydroxylase (PAH) in two environments. The assignment of the electron paramagnetic resonance spectrum of PAH to two, overlapping high-spin ferric signals is confirmed by computer simulation. Both environments are shown to be populated in the crude enzyme.
L. M. Bloom +2 more
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