Results 101 to 110 of about 23,946 (202)

Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase. [PDF]

Int J Mol Sci, 2022
Conde-Giménez M, Galano-Frutos JJ, Galiana-Cameo M, Mahía A, Victor BL, Salillas S, Velázquez-Campoy A, Brito RMM, Gálvez JA, Díaz-de-Villegas MD, Sancho J.   +10 more
europepmc   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Melatonin mediates phenolic acids accumulation in barley sprouts under MeJA stress

Frontiers in Nutrition
Phenolic acids are secondary metabolites in higher plants, with antioxidant, anticancer, and anti-aging effects on the human body. Therefore, foods rich in phenolic acids are popular.
Xin Tian, Renjiao Zhang, Zhengfei Yang, Jiangyu Zhu, Weiming Fang, Runqiang Yang, Yongqi Yin   +6 more
doaj   +1 more source

Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4500-4527, July 2026.
ABSTRACT Sweet potato (Ipomoea batatas) exhibits diversity in pigmentation and leaf morphology, yet the genetic architecture and regulatory organisation underlying these traits remain poorly resolved, particularly with respect to organ‐specific control.
Dong An, Tiechen Shen, Shiyu Wu, Yanshen Li, Weijuan Fan, Mengxiao Yan, Yinghui Meng, Xinyi Wang, Ximing Xu, Zunfu Lv, Ling Yuan, Jun Yang, Guoquan Lu, Hongxia Wang   +13 more
wiley   +1 more source

Mutations of the phenylalanine hydroxylase gene in patients with phenylketonuria in Shanxi, China

Genetics and Molecular Biology, 2012
The variation in mutations in exons 3, 6, 7, 11 and 12 of the phenylalanine hydroxylase (PAH) gene was investigated in 59 children with phenylketonuria (PKU) and 100 normal children.
Yong-An Zhou, Yun-Xia Ma, Quan-Bin Zhang, Wei-Hua Gao, Jian-Ping Liu, Jian-Ping Yang, Gai-Xiu Zhang, Xiao-Gang Zhang, Liang Yu   +8 more
doaj  

The Isoenzymes of Phenylalanine Hydroxylase in Humans [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1977
C E, Parker, J, Barranger, R, Newhouse, S, Bessman   +3 more
openaire   +2 more sources

Phenylalanine hydroxylase contributes to serotonin synthesis in mice. [PDF]

FASEB J, 2021
Mordhorst A, Dhandapani P, Matthes S, Mosienko V, Rothe M, Todiras M, Self J, Schunck WH, Schütz A, Bader M, Alenina N.   +10 more
europepmc   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, Volume 49, Issue 7, Page 3543-3559, July 2026.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

Impact of Fluorinated Ionic Liquids on Human Phenylalanine Hydroxylase-A Potential Drug Delivery System. [PDF]

Nanomaterials (Basel), 2022
Alves MMS, Leandro P, Mertens HDT, Pereiro AB, Archer M.   +4 more
europepmc   +1 more source

The Early Response to Urea, Nitrate, or Ammonium and Iron Resupply in Tomato Roots Highlights the Induction of FER, bHLHs, UMAMITs, and MATEs

Physiologia Plantarum, Volume 178, Issue 4, July/August 2026.
ABSTRACT Depending on the nitrogen (N) form available to roots, plants activate different transcriptional and metabolic pathways; this can consequently translate into differences in the composition and release of root exudates. To address the existing knowledge gap regarding the relationship between the availability of Iron (Fe) and different N forms ...
Arianna Lodovici, Leilei Zhang, Nicola Tomasi, Gabriella Vinci, Fabio Marroni, Barbara Piani, Fatemeh Hassanvand, Mustapha Arkoun, Luigi Lucini, Laura Zanin   +9 more
wiley   +1 more source