Cold Plasma Pretreatment Enhances Antioxidant Stability in Lime Fruit During Storage
This study investigates the use of cold plasma (CP) pretreatment, including dielectric barrier discharge (DBD) and gliding arc (GLIDE) plasma, to enhance the antioxidant properties and storage stability of lime. Results show that DBD plasma at 10 min significantly increases bioactive compounds, such as vitamin C and flavonoids, while extending the lime'
Ghazal Razazian +2 more
wiley +1 more source
Fenilcetonúria e suas variantes: revisão bibliográfica [PDF]
A fenilcetonúria representa o erro do metabolismo dos aminoácidos mais comum na população caucasiana, atingindo 1/10.000 nascimentos. Esta doença, de transmissão autossómica recessiva, resulta da deficiência em fenilalanina hidroxilase ou de erros no ...
Cardoso, Inês Lopes, Machado, Joana
core
This research provides novel insights into the role of the gut‐brain axis in the pathogenesis of AD and highlights Crocin's potential as a therapeutic candidate for improving both cognitive function and pathological outcomes in AD. We believe these findings have significant implications for understanding the interplay between gut microbiota and ...
Zhiyan Zou +6 more
wiley +1 more source
Birth prevalence of phenylalanine hydroxylase deficiency: a systematic literature review and meta-analysis. [PDF]
Foreman PK +7 more
europepmc +1 more source
Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase. [PDF]
Arturo EC +6 more
europepmc +1 more source
Metabolic engineering of functional phytochemicals [PDF]
Phytochemicals belonging to the group’s phenols, terpenes, betalains, organosulfides, indoles and protein inhibitors are important components in fruits, vegetables, legumes, whole grains and nuts that have health promoting benefits and a variety of ...
Abdul Hamid, Azizah +4 more
core
Distinct microbial and metabolic shifts characterize acute coronary syndrome and recovery
This study explores the gut–heart axis in coronary artery disease (CAD) using multi‐omics integration of clinical, microbiome and metabolome data. Across healthy controls, stable CAD (sCAD), acute coronary syndrome (ACS), and recovery, we identify stage‐specific microbial dysbiosis and metabolite alterations that mark the transition from stability to ...
Jing Xu +37 more
wiley +1 more source
Unravelling the Complex Denaturant and Thermal-Induced Unfolding Equilibria of Human Phenylalanine Hydroxylase. [PDF]
Conde-Giménez M, Sancho J.
europepmc +1 more source
The inactivation of phenylalanine hydroxylase by 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine and the aerobic oxidation of the latter. The effects of catalase, dithiothreitol and reduced nicotinamide–adenine dinucleotide [PDF]
Alexander Jakubovič +2 more
openalex +1 more source
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li +7 more
wiley +1 more source

