Results 71 to 80 of about 109,987 (177)

Impact of gut probiotic metabolites on phenylketonuria

Frontiers in Cellular and Infection Microbiology
Phenylketonuria is an unusual inherited metabolic disease induced by mutations of the phenylalanine hydroxylase gene, resulting in phenylalanine accumulation.
Anjana Kalla Veedu, Sujithra Vijayakumar, Hannah A. Joseph, John Thomas   +3 more
doaj   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

Plant, Cell &Environment, Volume 49, Issue 10, Page 7435-7448, October 2026.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang, Fengjiao Wang, Ran Du, Tao Li, Shaoqun Zhou, Jianbin Yan, Wei Li   +6 more
wiley   +1 more source

Two apparent molecular weight forms of human and monkey phenylalanine hydroxylase are due to phosphorylation

, 1984
Two apparent molecular weight forms of human and monkey phenylalanine hydroxylase are due to ...
BE Kemp (11862284), RG Cotton (14528132), WJ McAdam (14574962), Julian Mercer (13076475), SC Smith (11760032)   +4 more
core   +1 more source

The Reaction Mechanism of Phenylalanine Hydroxylase. – A Question of Coordination

Pteridines, 2005
Phenylalanine hydroxylase (PAH) is a non-heme iron and tetrahydrobiopterin-dependent enzyme that catalyzes the hydroxylation of L-phenylalanine to L-tyrosine using dioxygen as additional substrate.
Teigen Knut, Jensen Vidar R., Martinez Aurora   +2 more
doaj   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

Trastornos neurológicos a consecuencia de la mutación del gen que codifica para fenilalanina hidroxilas

Revista Ciencias Biomédicas, 2013
Introduction: Phenylketonuria (PKU) is an error of the metabolism of the amino acids due to the gene mutation that codifies for the enzyme called phenylalanine hydroxylase (PAH). 564 cases of mutations in different exons have been reported.
Alvear-Sedán Ciro, Barboza-Ubarnes Miriam, Stave-Salgado Karen   +2 more
doaj  

Anthocyanins and betalains in evolution: Why mutual exclusion remains the best‐supported model

Plant Biology, Volume 28, Issue 6, Page 1763-1766, October 2026.
Anthocyanins and betalains are plant pigments produced through different biosynthetic pathways and are generally considered mutually exclusive. We examine claims of their co‐occurrence, arguing that methodological flaws and data misinterpretation have led to unsupported reports, and offer recommendations for more rigorous future research.
B. Pucker, M. I. Khan
wiley   +1 more source

Interaction Energies between Tetrahydrobiopterin Analogues and Aromatic Residues in Tyrosine Hydroxylase and Phenylalanine Hydroxylase

, 2016
The phenylalanine residues 300 and 309 in the enzyme tyrosine hydroxylase are known to aid in the positioning and binding of tetrahydrobiopterin (BH4) to the enzyme active site. The residues phenylalanine 254 and tyrosine 325 similarly aid in binding BH4
Jessica N. Cross (2480065), Mauricio Cafiero (2480059), Meghan E. Hofto (2480062)   +2 more
core   +1 more source

Food Regime for Phenylketonuria: Presenting Complications and Possible Solutions

Journal of Multidisciplinary Healthcare, 2022
Sudipt Kumar Dalei, Nidhi Adlakha Regional Center for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, IndiaCorrespondence: Nidhi Adlakha Email nidhi.adlakha@rcb.res.inAbstract: In the category of rare inherited genetic disorders ...
Kumar Dalei S, Adlakha N
doaj  

Cytochrome P450 enzymes in the phenylpropanoid pathway: CYP73 and CYP98 candidate genes in Chara braunii, Anthoceros agrestis, Marchantia polymorpha and Physcomitrium patens

The Plant Journal, Volume 128, Issue 1, October 2026.
SUMMARY CYP73 and CYP98 are two cytochrome P450 monooxygenase families present in bryophytes and tracheophytes, and they play key roles in the formation of phenolic compounds containing a caffeic acid moiety and more complex phenolic compounds. CYP73 encodes the second enzyme in the core phenylpropanoid pathway and is the first enzyme family in this ...
Christoph E. G. Aggarwal‐Kentrath, Maike Petersen   +1 more
wiley   +1 more source