Results 71 to 80 of about 624 (116)

4-Phenylbutyric Acid Reduces the Proliferation in Colon Cancer Cell Lines Through Modulating the Cell Cycle Regulatory Genes: An In Silico and In Vitro Approach. [PDF]

Cancer Rep (Hoboken)
Deka D, Das A, Baildya N, Nagainallur Ravichandran S, Pathak S, Banerjee A, Duttaroy AK.   +6 more
europepmc   +1 more source

Chronic hypoxia induces liver injury via PKCδ/ASMase-driven ceramide accumulation and endoplasmic reticulum stress in rats. [PDF]

Lipids Health Dis
Huang Y, Ding Y, Guo X, Huang L, Meng X, Jiang W, Wang Z, Yang T, Zheng M, Tan X.   +9 more
europepmc   +1 more source

A possibility of uncoupling protein 1 induction with the enhancement of myogenesis related to ruminal fermentation. [PDF]

Sci Rep
Diao Z, Jia S, Itoyama E, Yoshioka H, Murakami M, Funaba M.   +5 more
europepmc   +1 more source

Elimination of Mother-to-Child Transmission of Hepatitis B Virus in Gulf Cooperation Council Countries: Current Status and Future Prospects. [PDF]

Am J Trop Med Hyg
Al Awaidy S, Tohme RA, Al Romaihi HE, Ezzikouri S, Mahomed O.   +4 more
europepmc   +1 more source

4-Phenyl Butyric Acid (4-PBA) Suppresses Neutrophil Recruitment in a Murine Model of Acute Perinatal Inflammation. [PDF]

J Immunol Res
Gille C, Jungwirth M, Pezer S, Dietz-Ziegler S, Köstlin-Gille N, Lajqi T.   +5 more
europepmc   +1 more source

Endoplasmic Reticulum Stress: A Novel Target for the Prevention and Treatment of Hypertension and Its Related Diseases. [PDF]

J Cell Mol Med
Ma X, Si F, Ma J, Feng C, Wang Y, Wang L, Yu J.   +6 more
europepmc   +1 more source

Therapeutic potential of 4-phenylbutyric acid against methylmercury-induced neuronal cell death in mice. [PDF]

Arch Toxicol
Miki R, Nomura R, Iijima Y, Kubota S, Takasugi N, Iwawaki T, Fujimura M, Uehara T.   +7 more
europepmc   +1 more source

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Sodium Phenylbutyrate and Ursodoxicoltaurine: First Approval

CNS Drugs, 2022
An oral, fixed-dose coformulation of sodium phenylbutyrate and ursodoxicoltaurine (ALBRIOZA™; hereafter denoted sodium phenylbutyrate/ursodoxicoltaurine) is being developed by Amylyx Pharmaceuticals for the treatment of neurodegenerative diseases. In June 2022, the coformulation received its first approval with conditions in Canada for the treatment of
openaire   +2 more sources

Sodium Phenylbutyrate-Ursodoxicoltaurine (Albrioza)

Canadian Journal of Health Technologies, 2022
CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments ...
openaire   +1 more source

Radioprotection by the histone deacetylase inhibitor phenylbutyrate

Radiation and Environmental Biophysics, 2011
The histone deacetylase inhibitor (HDAC), phenylbutyrate (PB), is a novel anti-tumor agent. Studies have demonstrated that HDAC inhibitors can suppress cutaneous radiation syndrome and stimulate hematopoiesis. The objective of this study was to test the ability of PB treatment to protect against acute gamma-radiation-induced lethality in the DBA/2 ...
Alexandra C, Miller, Stuart, Cohen, Michael, Stewart, Rafael, Rivas, Paul, Lison   +4 more
openaire   +2 more sources