Results 81 to 90 of about 624 (116)

USE OF 4-PHENYLBUTYRIC ACID AND/OR 3-PHENYLBUTYRIC ACID AND/OR 2-PHENYLBUTYRIC ACID IN PREVENTING AND TREATING CRYPTOGAMIC DISEASES

2021
La présente invention concerne l'utilisation de l'acide 2-phénylbutyrique, ou de l'acide 3-phénylbutyrique, ou de l'acide 4-phénylbutyrique, ou de l'un de leurs sels, ou de l'une de leurs combinaisons, pour lutter contre les maladies cryptogamiques causées par les champignons et les oomycètes.
Cacas, Jean-Luc, Vasselon, Damien, Lamotte, Olivier, Poinssot, Benoit, Walker, Anne-Sophie   +4 more
openaire   +2 more sources

Developing a new formulation of sodium phenylbutyrate

Archives of Disease in Childhood, 2012
BackgroundSodium phenylbutyrate (NaPB) is used as a treatment for urea cycle disorders (UCD). However, the available, licensed granule form has an extremely bad taste, which can compromise compliance and metabolic control.ObjectivesA new, taste-masked, coated-granule formulation (Luc 01) under development was characterised for its in vitro taste ...
Nathalie, Guffon, Yves, Kibleur, William, Copalu, C, Tissen, Joerg, Breitkreutz   +4 more
openaire   +2 more sources

Sodium Phenylbutyrate and Ursodoxicoltaurine (Albrioza)

Canadian Journal of Health Technologies, 2022
CADTH recommends that Albrioza be reimbursed by public drug plans for the treatment of patients with amyotrophic lateral sclerosis (ALS) if certain conditions are met. Albrioza should only be covered to treat those who have a diagnosis of definite ALS, have had symptoms for 18 months or less, have a forced vital capacity (FVC) of at least ...
openaire   +1 more source

Phenylbutyrate for monogenetic epilepsy: Literature review

Epilepsy Research
Monogenetic epilepsies are seizure disorders with a single-gene etiology. More than 500 genes are linked to epilepsy. As many as 40 % of epilepsies are caused by variants in one of these genes. Single gene-linked epilepsies have a wide phenotypic spectrum and may be accompanied by comorbidities such as developmental and motor delays.
Amelia, Stone, Jacqueline, Burré, Natalie, Wayland, Zachary M, Grinspan   +3 more
openaire   +2 more sources

Degradation of 3-phenylbutyric acid by Pseudomonas sp

Journal of Bacteriology, 1982
Pseudomonas sp. isolated by selective culture with 3-phenylbutyrate (3-PB) as the sole carbon source metabolized the compound through two different pathways by initial oxidation of the benzene ring and by initial oxidation of the side chain. During early exponential growth, a catechol substance identified as 3-(2,3-dihydroxyphenyl)butyrate (2,3-DHPB ...
F S, Sariaslani, J L, Sudmeier, D D, Focht   +2 more
openaire   +2 more sources

Neuroprotective Effects of Phenylbutyrate Against MPTP Neurotoxicity

NeuroMolecular Medicine, 2004
There is increasing evidence that administration of histone deacetylase (HDAC) inhibitors can exert neuroprotective effects by a variety of mechanisms. Phenylbutyrate is a well-known HDAC inhibitor, which increases gene transcription of a number of genes, and also exerts neuroprotective effects.
Gabriella, Gardian, Lichuan, Yang, Carine, Cleren, Noel Y, Calingasan, Peter, Klivenyi, M Flint, Beal   +5 more
openaire   +2 more sources

Sodium Phenylbutyrate and Taurursodiol

American Journal of Health-System Pharmacy, 2023
openaire   +2 more sources

Sodium Phenylbutyrate/Taurursodiol

Clinical Therapeutics, 2023
openaire   +2 more sources

Glycerol-phenylbutyrate

Reactions Weekly, 2023
openaire   +1 more source

Sodium Phenylbutyrate–Taurursodiol for ALS

New England Journal of Medicine, 2020
Joachim, Herz, Olaf, Stüve
openaire   +3 more sources