Results 21 to 30 of about 974 (165)

Occurrence of herbicides and their transformation products in sewage sludge: a review

Plant, Soil and Environment
The beneficial reuse of sewage sludge in agricultural soils is limited by the accumulation of micropollutants of emerging concern, which may pose significant environmental and human health risks.
Madhusha Mihirani Subasinghe, Filip Mercl, Sreynet Nang, Altyn Taisheva, Pavel Tlustoš   +4 more
doaj   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng, Belén Lucas, Philipp Lampe, Stefano Ugel, Suyuan Chen, Anke Unger, Matthias Bischoff, Soheila Rezaei Adariani, Kesava Reddy Naredla, Kamal Kumar, Annika Schmidt, Carsten Strohmann, Petra Janning, Raphael Gasper, María Lucas, Malte Gersch, Sonja Sievers, Vincenzo Bronte, Slava Ziegler, Herbert Waldmann   +19 more
wiley   +1 more source

Analysis of triacylglycerol and phospholipid sn‐positional isomers by liquid chromatographic and mass spectrometric methodologies

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 4-36, January/February 2026.
Abstract Analysis of triacylglycerol (TG) and phospholipid sn‐positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods.
Mikael Fabritius, Baoru Yang
wiley   +1 more source

Chiral stationary phases for liquid chromatography based on chitin- and chitosan-derived marine polysaccharides [PDF]

, 2017
The development of chiral stationary phases (CSPs) for liquid chromatography (LC) revolutionized the enantioseparation and, nowadays, different types of CSPs are commercially available.
Fernandes C., Pinto M.M.M., Ribeiro J., Tiritan M.E.   +3 more
core   +1 more source

Enantioseparation of 5,5'-Dibromo-2,2'-Dichloro-3-Selanyl-4,4'-Bipyridines on Polysaccharide-Based Chiral Stationary Phases: Exploring Chalcogen Bonds in Liquid-Phase Chromatography [PDF]

, 2021
he chalcogen bond (ChB) is a noncovalent interaction based on electrophilic features of regions of electron charge density depletion (σ-holes) located on bound atoms of group VI.
Aubert, Emmanuel, Chankvetad, Bezhan, Cossu, Sergio, Dallocchio, Rober, Dessì, Alessandro, Gatti, Carlo, Ghanem, Ashraf, Mamane, Victor, Mcphee, Derek, J, Pale, Patrick, Peluso, Paola, Sechi, Barbara, Weiss, Robin   +12 more
core   +3 more sources

Recent Synthetic Advances in C–H/N–H Functionalization of 1H‐Pyrazoles: Diverse Strategies Across Variously Substituted Scaffolds

The Chemical Record, Volume 25, Issue 12, December 2025.
Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür, Asta Žukauskaitė, Algirdas Šačkus, Eglė Arbačiauskienė   +3 more
wiley   +1 more source

Anticholinesterases [PDF]

, 2018
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are known serine hydrolase enzymes responsible for the hydrolysis of acetylcholine (ACh).
Alagöz, Mehmet Abdullah, Özdemir, Zeynep   +1 more
core   +1 more source

Hydrogen Peroxide‐Responsive Aminoferrocene Prodrugs

European Journal of Organic Chemistry, Volume 28, Issue 33, September 20, 2025.
To improve sensitivity toward H2O2, the boronic acid pinacol ester in known aminoferrocene‐based anticancer prodrug 13b is replaced with an α‐ketamide fragment to obtain prodrug 2a and some of its N‐alkylated derivatives. 2a exhibits substantially improved cytotoxicity in vitro toward ovarian cancer A2780 and Burkitt's lymphoma BL‐2 cells.
Marlies Körber, Jennifer Rühle, Fabian Halter, Andriy Mokhir   +3 more
wiley   +1 more source

Good data with `bad' reflections: the employment of non‐spherical scattering factors in the redetermination of the structure of O‐ethyl N‐phenylcarbamate

Acta Crystallographica Section C, Volume 81, Issue 8, Page 455-461, August 2025.
The structure of O‐ethyl N‐phenylthiocarbamate has been redetermined. Layers of hydrogen‐bonded dimers lie parallel to (031). A refinement using nonspherical scattering factors greatly reduced the number and severity of badly‐fitting reflections.The structure of O‐ethyl N‐phenylthiocarbamate, C9H11NOS (2), has been redetermined, confirming the results ...
Peter G. Jones
wiley   +1 more source

Serotonin receptors: Subtypes, functional responses and therapeutic relevance [PDF]

, 1995
Recent, rapid progress in the molecular biology of serotonin (5-HT) receptors requires conceptual re-thinking with respect to receptor classification.
Saxena, P.R. (Pramod Ranjan)
core   +1 more source