Results 111 to 120 of about 49,790 (238)

Changes in heart rate, dP/dt max, and dP/dt min with phenylephrine injection.

, 2013
(A): Heart rate before phenylephrine injection (baseline), at Inflection Point (IP), at middle point of phase II (MP), and at the maximum effects of phenylephrine (Peak).
Douglas F. Larson (400295), James Ranger-Moore (400296), Bo Yang (104813)   +2 more
core   +1 more source

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Age‐related loss of hysteresis in the spontaneous vascular sympathetic baroreflex is associated with altered neural rather than mechanical control

Experimental Physiology, EarlyView.
Abstract The vascular sympathetic baroreflex is critical for stabilising blood pressure. A notable feature of this reflex is hysteresis, a directional asymmetry in responsiveness during rising versus falling pressure that is evident in young adults but attenuated in older age.
Guto Wyn Hughes, Denis J. Wakeham, Christopher J. A. Pugh, Zoe H. Adams, Rachel N. Lord, Jonathan P. Moore   +5 more
wiley   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Dose-Response Study of Phenylephrine for Preventing Spinal-Induced Hypotension During Cesarean Delivery with Combined Spinal-Epidural Anesthesia Under the Effect of Prophylactic Intravenous Ondansetron

Drug Design, Development and Therapy
Xiao-Xia Sun, Jing Qian, Jia-Ming Fan, Lin Liu, Xia-Fang Jin, Fei Xiao Department of Anesthesia, Jiaxing University Affiliated Women and Children Hospital, Jiaxing City, People’s Republic of ChinaCorrespondence: Xia-Fang Jin; Fei Xiao, Department of ...
Sun XX, Qian J, Fan JM, Liu L, Jin XF, Xiao F   +5 more
doaj  

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Author Correction: A comparative study of the local effect of tranexamic acid and phenylephrine on the amount of bleeding in rhinoplasty: A randomized clinical trial [PDF]

Caspian Journal of Internal Medicine
After the publication of the article titled “A Comparative Study of the Local Effect of Tranexamic Acid and Phenylephrine on the Amount of Bleeding in Rhinoplasty: A Randomized Clinical Trial”, it was noticed that the name of Behrooz Gandomi had been ...
Hooshang Akbari, Ebrahim Nasiri Formi, Abbas Alipour, Hamed Delam, Esmaeil Kavi, Behrooz Gandomi, Negar Shahkarami   +6 more
doaj  

Compared effects on cerebral oxygenation of ephedrine vs phenylephrine to treat hypotension during carotid endarterectomy

, 2017
International audienceWhile both ephedrine and phenylephrine are currently used to treat hypotension occurring during carotid endarterectomy (CEA) under general anaesthesia, phenylephrine may have deleterious effects on the cerebral watershed, due to its
Eugenio Rosset, Jugurtha Aliane, Pereira, Bruno, Baud, Charlotte, Christian Dualé, Pierre Schoeffler, Charlotte Baud, Aliane, Jugurtha, Rosset, Eugenio, Bouvier, Damien, Guesmi, Nader, Nader Guesmi, Damien Bouvier, Schoeffler, Pierre, Dualé, Christian, Bruno Pereira   +15 more
core   +1 more source

Haloperidol for Hypoactive and Hyperactive Delirium in ICU Patients—A Post Hoc Bayesian Analysis of the AID‐ICU Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Delirium is clinically classified into hypoactive or hyperactive motoric subtypes, which may have different responses to treatment. We assessed heterogeneity in treatment effects according to baseline motoric subtype in the AID‐ICU trial, which randomised adult ICU patients with delirium to haloperidol versus placebo.
Nina C. Andersen‐Ranberg, Lone Musaeus Poulsen, Anders Perner, Johanna Hästbacka, Matthew Morgan, Giuseppe Citerio, Stine Estrup Damby, Camilla Bekker Mortensen, Marie Oxenbøll Collet, Sven‐Olaf Weber, Anne Sofie Andreasen, Morten Bestle, Bülent Uslu, Helle Scharling Pedersen, Louise Gramstrup Nielsen, Kjeld Damgaard, Troels Bek Jensen, Trine Sommer, Nilanjan Dey, Ole Mathiesen, Anders Granholm   +20 more
wiley   +1 more source

An alternative synthesis of (±)-phenylephrine hydrochloride [PDF]

Maejo International Journal of Science and Technology, 2014
This study presents alternative synthetic pathways and reagents for the preparation of racemic phenylephrine hydrochloride. Using m-hydroxybenzaldehyde as starting material, two separate pathways–epoxidation and bromohydrin formation–are
Aphiwat Teerawutgulrag, Wipanoot Baison, Pakawan Puangsombat, Nuansri Rakariyatham   +3 more
doaj