Results 131 to 140 of about 49,790 (238)

Effects of epinephrine, norepinephrine, and phenylephrine on microcirculatory blood flow in the gastrointestinal tract in sepsis

open access: yes, 2006
OBJECTIVE: The use of vasopressors for treatment of hypotension in sepsis may have adverse effects on microcirculatory blood flow in the gastrointestinal tract.
Hiltebrand, Luzius B   +2 more
core   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu   +8 more
wiley   +1 more source

Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang   +8 more
wiley   +1 more source

Chloroquine Inhibits Contraction Elicited by the Alpha-1 Adrenoceptor Agonist Phenylephrine in the Isolated Rat Aortas

open access: yes
Although chloroquine appears to inhibit the alpha-1 adrenoceptor, whether the chloroquine-mediated inhibition of phenylephrine-induced contraction is associated with the blockade of alpha-1 adrenoceptors remains unknown. This study examined the effect of
Seung Hyun Ahn   +6 more
core   +1 more source

Altered Neurovascular Coupling Dynamics During Dobutamine‐Induced Acute Stress

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background Neurovascular coupling (NVC) is essential for regulating brain metabolism and energy supply and may be altered under acute stress. This study aimed to investigate how acute stress induced by dobutamine affects NVC. Materials and methods This study enrolled 38 healthy participants undergoing a resting‐state fMRI scan and an arterial ...
Rui Wang   +10 more
wiley   +1 more source

"INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"

open access: yesActa Medica Iranica, 2004
It has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. The exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and
T. Mashhoodi   +1 more
doaj  

Repositioning of Vertical Implantable Phakic Contact Lens

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
Vertical orientation of Implantable Phakic Contact Lens. ABSTRACT Implantable phakic contact lens (IPCL) V2.0 has a special patterned hole on the leading left corner to ensure correct orientation and positioning. Incorrect orientation is an absolute indication for repositioning.
Sushank Bhalerao   +4 more
wiley   +1 more source

Timely Extracorporeal Cardiopulmonary Resuscitation for Intraoperative Cardiac Arrest Caused by Suspected Bone Cement Implantation Syndrome: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Bone cement implantation syndrome should be suspected in patients with sudden circulatory collapse during cemented orthopedic surgery. Prompt recognition and timely extracorporeal cardiopulmonary resuscitation may improve neurological outcomes in carefully selected patients.
Yuta Kikuchi   +2 more
wiley   +1 more source

Heart rate control in paediatric coronary CT angiography using phenylephrine

open access: yes
AIMS: Obtaining images of diagnostic quality using coronary CT angiography (CCTA) depends, in part, upon a patient\u2019s heart rate (HR) at time of scanning. HR reduction is most commonly achieved with beta blockers.
Chernovolenko, Margarita   +9 more
core   +1 more source

Early Detection of Clinical Deterioration in ICU Patients With Respiratory Failure Receiving Vasoactive Support: A Machine Learning Approach to Identifying High‐Risk Individuals

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Acute respiratory failure requiring intensive care is frequently accompanied by hemodynamic instability, necessitating vasoactive pharmacologic support, and elevated mortality. We aimed to develop and validate a machine learning model to stratify all‐cause in‐hospital mortality risk in ICU patients with respiratory failure ...
Mohammad Fathi   +8 more
wiley   +1 more source

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