Results 121 to 130 of about 63,750 (296)

Effect on Neonatal Acid–Base Status of Phenylephrine and Norepinephrine Boluses for Management of Spinal Anesthesia-Induced Hypotension in Patients with Preeclampsia Undergoing Cesarean Delivery: A Randomized, Double-Blinded Trial

Journal of Obstetric Anaesthesia and Critical Care
Purpose: Phenylephrine (PE) is the vasopressor of choice for spinal induced hypotension. In recent studies, norepinephrine (NE) has been used to manage hypotension following spinal anesthesia.
Trina Sen, Prerona Saha, Pranab Kalita, Priyam Saikia, Bandana Mahanta   +4 more
doaj   +1 more source

Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals [PDF]

, 2019
Importance: Sepsis is present in many hospitalizations that culminate in death. The contribution of sepsis to these deaths, and the extent to which they are preventable, is unknown.
Anderson, Deverick J, Dantes, Raymund B, Epstein, Lauren, Hamad, Yasir, Jones, Travis M, Klompas, Michael, O\u27Brien, Cara, Pande, Anupam, Rhee, Chanu, Varon, Jack, Warren, David K   +10 more
core   +1 more source

Nutrigenomic insights and cardiovascular benefits of blackberry (Rubus ulmifolius Schott.) and mugwort (Artemisia campestris L.)

Experimental Physiology, EarlyView.
Abstract Blackberry (Rubus ulmifolius Schott) and mugwort (Artemisia campestris L.) are plants traditionally used to treat various pathologies, including hypertension. The vasodilatory and hypotensive effects of blackberry were investigated through experiments in rat models (n = 5 rats per group) and compared with those of mugwort, which had been ...
Afaf Mehiou, Anca Lucau‐Danila, Zachee L. E. Akissi, Chaimae Alla, Nourelhouda Bouanani, Abdelkhaleq Legssyer, Jean‐Louis Hilbert, Sevser Sahpaz, Abderrahim Ziyyat   +8 more
wiley   +1 more source

Expression of Smooth Muscle Myosin Heavy Chains and Unloaded Shortening in Single Smooth Muscle Cells [PDF]

, 1997
The functional significance of the variable expression of the smooth muscle myosin heavy chain (SM-MHC) tail isoforms, SM1 and SM2, was examined at the mRNA level (which correlates with the protein level) in individual permeabilized rabbit arterial ...
Eddinger, Thomas, Meer, Daniel P.
core   +1 more source

Trifluoperazine, an inhibitor of calmodulin action, antagonises phenylephrine‐induced metabolic responses and mitochondrial calcium fluxes in liver [PDF]

, 1980
Peter H. Reinhart, Wayne M. Taylor, Fyfe L. Bygrave   +2 more
openalex   +1 more source

TRPV1 blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin‐induced renal injury in rats

Experimental Physiology, EarlyView.
Abstract Renal injury is associated with inflammatory responses within the kidney which could involve activation of transient receptor potential vanilloid 1 (TRPV1) channels. This study investigated whether TRPV1 channels modulate baroreflex regulation of renal sympathetic nerve activity (RSNA) in a rat model of cisplatin‐mediated renal injury.
Mohammed H. Abdulla, Ella Murphy, Lauren Mulcahy, Edward J. Johns   +3 more
wiley   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Comparison of phenylephrine and mephentermine for preventing oxytocin-induced hemodynamic changes during spinal anaesthesia

Journal of Medical and Scientific Research
Background: Spinal anaesthesia is a safe and reliable regional technique for the caesarean section, offering rapid onset, effective analgesia and reduced aspiration risk compared to general anaesthesia.
Garg A, Rehman S, Bhatia R, Pathania J
doaj   +1 more source

Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa, Pablo S. Gaete, Ping Shu, Priscila A. Araujo, Annie V. Beuve, Walter N. Durán, Jorge E. Contreras, Mauricio A. Lillo   +7 more
wiley   +1 more source

Therapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure. [PDF]

, 2019
Background Branched-chain amino acid (BCAA) catabolic defect is an emerging metabolic hallmark in failing hearts in human and animal models. The therapeutic impact of targeting BCAA catabolic flux under pathological conditions remains understudied ...
Chen, Mengping, Chuang, David T, Gao, Chen, Ren, Shuxun, Sun, Haipeng, Wang, Menglong, Wang, Yibin, Wynn, R Max, Yu, Jiayu   +8 more
core   +1 more source