Experimental Physiology, EarlyView.Abstract This study aimed to determine whether sodium nitrite supplementation prevented chronic stress‐induced cerebrovascular dysfunction and cognitive decline. We hypothesize that nitrite supplementation will prevent the oxidative environment and cerebrovascular dysfunction associated with chronic stress and maintain cognitive health.
Emily Burrage +10 more
wiley +1 more source
Combination of 5% phenylephrine and 0.5% tropicamide eyedrops for pupil dilation in neonates is twice as effective as 0.5% tropicamide eyedrops alone [PDF]
, 2016 Anne‐Laure Lux +4 more
openalex +1 more source
Experimental Physiology, EarlyView.Abstract Attenuation of sympathetic vasoconstriction during exercise (functional sympatholysis) contributes to skeletal muscle oxygen delivery–utilization matching. However, the extent to which muscle contractions impact noradrenergic regulation of interstitial oxygen pressures (PO2is${P_{{{\mathrm{O}}_2}}}_{{\mathrm{is}}}$; the driving force for blood–
Edward T. N. Calvo +10 more
wiley +1 more source
Comparison of two minimally invasive cardiac-output monitoring systems with different algorithms
Fujita Medical Journal, 2016 Objectives: Minimally invasive haemodynamic monitoring is important in goal-directed therapy. The algorithms used by the FloTrac/Vigileo (FV) and lithium dilution cardiac output rapid (LiDCOrapid) (LR) measurement systems for cardiac output (CO ...
Yoshitaka Hara +6 more
doaj +1 more source
Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]
, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto +10 more
core +2 more sources
Activation of α1A‐adrenoceptors desensitizes the rat aorta response to phenylephrine through a neuronal NOS pathway, a mechanism lost with ageing [PDF]
, 2017 Cristina Arce +12 more
openalex +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, EarlyView.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Influence of central venous pressure upon sinus node responses to arterial baroreflex stimulation in man [PDF]
Measurements were made of sinus node responses to arterial baroreceptor stimulation with phenylephrine injection or neck suction, before and during changes of central venous pressure provoked by lower body negative pressure or leg and lower truck ...
Abboud, F. M. +3 more
core +1 more source
Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function [PDF]
, 2014 <b>Objective:</b><p></p> Mitochondria-derived reactive oxygen species (ROS) play important roles in the development of cardiovascular disease highlighting the need for novel targeted therapies.
Adlam +41 more
core +1 more source
Phenylephrine Increases Regional Cerebral Blood Flow Following Hemorrhage during Isoflurane–Oxygen Anesthesia [PDF]
, 1989 W. Alan C. Mutch +2 more
openalex +1 more source