Results 141 to 150 of about 63,750 (296)

Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 15, Page 3669-3687, August 2025.
Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia   +14 more
wiley   +1 more source

Does an Earlier or Late Intravenous Injection of Ondansetron Affect the Dose of Phenylephrine Needed to Prevent Spinal-Anesthesia Induced Hypotension in Cesarean Sections?

open access: yesDrug Design, Development and Therapy, 2020
Jing Qian,1 Lin Liu,1 Xiufeng Zheng,2 Fei Xiao1 1Department of Anesthesia, Jiaxing University Affiliated Women and Children Hospital, Jiaxing, People’s Republic of China; 2Department of Obstetrics, Jiaxing University Affiliated Women and Children ...
Qian J, Liu L, Zheng X, Xiao F
doaj  

Influence of central venous pressure upon sinus node responses to arterial baroreflex stimulation in man [PDF]

open access: yes
Measurements were made of sinus node responses to arterial baroreceptor stimulation with phenylephrine injection or neck suction, before and during changes of central venous pressure provoked by lower body negative pressure or leg and lower truck ...
Abboud, F. M.   +3 more
core   +1 more source

Inside‐Out IP3‐Mediated G Protein‐Coupled Receptor Activation Drives Intercellular Ca2+ Signaling in the Vascular Endothelium

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
During endothelial cell Ca2+ wave propagation, IP3 in the initiating cell activates IP3Rs on the endoplasmic reticulum, releasing Ca2+ into the cytoplasm. We show that IP3 is required for signal propagation to neighboring cells and propose that this is due to activation of membrane‐bound pore‐dead IP3Rs, as part of a noncanonical signaling inside‐out ...
C. Buckley   +4 more
wiley   +1 more source

Postoperative bilateral visual loss after a single dose of tranexamic acid

open access: yesAnaesthesia Reports, Volume 13, Issue 2, July‐December 2025.
Summary A 32‐year‐old woman presented with transient visual loss following the intra‐operative administration of a single intravenous dose of tranexamic acid during urgent cholecystectomy. Apart from obesity, the patient had no notable medical history or pre‐existing ocular conditions.
B. Chevalley   +4 more
wiley   +1 more source

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

open access: yesGlia, Volume 73, Issue 7, Page 1398-1419, July 2025.
Main Points Astrocytes play an important role in glaucoma. These cells express Cx43 which can form gap junctions and hemichannels. This study shows Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation.
Khulan Batsuuri   +4 more
wiley   +1 more source

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