Results 151 to 160 of about 66,103 (276)

Decreased reactive oxygen species production and NOX1, NOX2, NOX4 expressions contribute to hyporeactivity to phenylephrine in aortas of pregnant SHR

, 2015
Jéssica Antonini Troiano, Simone R. Potje, Murilo E. Graton, Priscila Cavalari, Ariana Aparecida Ferreira Pereira, Gabriel Tavares do Vale, Ana Cláudia de Melo Stevanato Nakamune, Dóris Hissako Sumida, Carlos R. Tirapelli, Cristina Antoniali   +9 more
openalex   +1 more source

PHENYLEPHRINE-INDUCED HYPERTENSION DECREASES THE EXTENT OF ISCHEMIA FOLLOWING MIDDLE CEREBRAL ARTERY OCCLUSION IN THE RAT [PDF]

, 1988
Yong Seok Oh, John C. Drummond, D. J. Cole, Harvey M. Shapiro   +3 more
openalex   +1 more source

Endothelium‐Independent Relaxation of Alkaloid Boldine in Isolated Aortas From Normotensive and Hypertensive Rats: Participation of Ca2+ Channels

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo, Rita de Cássia Vilhena da Silva, Valdir Cechinel Filho, Priscila de Souza   +3 more
wiley   +1 more source

Impact of Endothelial Diversity and Dysfunction on Cardiovascular Disease

Comprehensive Physiology, Volume 15, Issue 6, December 2025.
The vascular endothelium is highly diverse, regulating permeability, vascular tone, repair, and inter‐organ communication. Endothelial heterogeneity supports tissue‐specific needs, but dysfunction drives cardiovascular disease. Transcriptomics, in vitro models, and redox signaling studies reveal therapeutic targets for precision treatment of ...
Anna E. Williams, Luke S. Dunaway, Zuzanna J. Juśkiewicz, Wyatt J. Schug, Miriam M. Cortese‐Krott, Michael Koval, Brant E. Isakson   +6 more
wiley   +1 more source

Prevalence, underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals [PDF]

, 2019
Importance: Sepsis is present in many hospitalizations that culminate in death. The contribution of sepsis to these deaths, and the extent to which they are preventable, is unknown.
Anderson, Deverick J, Dantes, Raymund B, Epstein, Lauren, Hamad, Yasir, Jones, Travis M, Klompas, Michael, O\u27Brien, Cara, Pande, Anupam, Rhee, Chanu, Varon, Jack, Warren, David K   +10 more
core   +1 more source

Combination of 5% phenylephrine and 0.5% tropicamide eyedrops for pupil dilation in neonates is twice as effective as 0.5% tropicamide eyedrops alone [PDF]

, 2016
Anne‐Laure Lux, A. Degoumois, Amandine Barjol, F. Mouriaux, É. Denion   +4 more
openalex   +1 more source

Bisphenol A‐Induced Vascular Endothelial Dysfunction: Protective Effects of Nigella sativa Oil and Thymoquinone

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
BPA exposure in rats and HUVECs impaired aortic contractility, increased lipid peroxidation, ROS, NO, VCAM‑1, and p‑eNOS, and blunted relaxant responses. Co‑treatment with NSO or TQ restored KCl/PE‑induced contractions, enhanced ACh‑ and SNP‑mediated vasorelaxation, and lowered oxidative/nitrosative stress and adhesion molecule expression.
Masoumeh Fadishei, Mahdieh Sadat Mohsenzadeh, Bibi Marjan Razavi, Mohsen Imenshahidi, Seyed Ahmad Mohajeri, Mahboubeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh   +6 more
wiley   +1 more source

Phenylephrine-induced vasoconstriction of the rat superior mesenteric artery is decreased after repeated swimming

, 2004
Agnaldo Bruno Chies, Ana Maria de Oliveira, Fabiana C. Pereira, Cláudia Regina de Andrade, Fernando Morgan de Aguiar Corrêa   +4 more
openalex   +2 more sources

Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
In this review, we summarize cell–ECM interactions and delve into the complex mechanotransduction. We introduce advanced research methods and emerging clinical tools used to study cellular mechanical phenotypes, mechanotransduction, and disease progression. Additionally, we analyze the role of mechanical biomarkers in the development and progression of
Yicen Long, Peng Wang, Jiacheng Lei, Baihai Su, Qiang Wei, Xiaojing Liu   +5 more
wiley   +1 more source

Early NADPH oxidase-2 activation is crucial in phenylephrine-induced hypertrophy of H9c2 cells

, 2014
Nynke E. Hahn, René J.P. Musters, Jan Fritz, Patrick J. Pagano, Alexander B.A. Vonk, Walter J. Paulus, Albert C. van Rossum, Christof Meischl, Hans W.M. Niessen, Paul A.J. Krijnen   +9 more
openalex   +2 more sources