Results 151 to 160 of about 63,750 (296)

Safety Assessment of a 1940 nm Tm:YAP Laser for Fractional Skin Ablation in a Swine Model

open access: yesLasers in Surgery and Medicine, Volume 57, Issue 5, Page 405-414, July 2025.
ABSTRACT Objectives This exploratory study was aimed to evaluate the safety and preliminary efficacy of Epicare, a 1940 nm thulium‐doped yttrium aluminum perovskite (Tm:YAP) laser, for fractional skin ablation in a swine model. The goal was to assess collagen remodeling and tissue responses across varied laser settings to optimize skin resurfacing ...
Yuval Ramot   +7 more
wiley   +1 more source

Analgesic Effect of Cocaine and Lidocaine/Xylometazoline in Healthy Volunteers Undergoing Awake Nasal Intubation: A Randomized Controlled Crossover Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Background Several drugs may be used to minimize pain during nasal intubation in awake patients. We hypothesized that the analgesic effect of cocaine would be at least as good (non‐inferior) as that of lidocaine with xylometazoline rated as maximum pain felt during awake nasal intubation of healthy volunteers.
Mo Haslund Larsen   +8 more
wiley   +1 more source

Patient considerations in cataract surgery – the role of combined therapy using phenylephrine and ketorolac

open access: yesPatient Preference and Adherence, 2016
Roberto Gonzalez-Salinas,1,2 Adriano Guarnieri,3 María Concepción Guirao Navarro,3 Manuel Saenz-de-Viteri3 1Department of Biomedical Research, Universidad Autónoma de Querétaro, Querétaro, Mexico; 2Department of ...
Gonzalez-Salinas R   +3 more
doaj  

Fourth Generation FloTrac Software Pulse Contour Analysis for Measuring and Trending Cardiac Output: A Method Comparison Study

open access: yesActa Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Background Accurate cardiac output assessment is crucial for evaluating hemodynamic status and guiding therapeutic interventions. The fourth generation FloTrac software (the FloTrac method) provides minimally invasive, continuous, and real‐time cardiac output estimations.
Caroline Dinesen   +4 more
wiley   +1 more source

Progress on the development of Class A GPCR‐biased ligands

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3249-3300, July 2025.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales   +20 more
wiley   +1 more source

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