Results 61 to 70 of about 61,478 (225)

Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]

, 1993
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J., Gratzl, Manfred, Mayerhofer, Artur, Rosenbusch, B., Rudolf, M., Sterzik, K.   +5 more
core   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Prediction of preload dependency using phenylephrine-induced peripheral perfusion index during general anaesthesia: a prospective observational study

BMC Anesthesiology
Background Tracking preload dependency non-invasively to maintain adequate tissue perfusion in the perioperative period can be challenging.The effect of phenylephrine on stroke volume is dependent upon preload.
Yusuke Iizuka, Koichi Yoshinaga, Shizuka Amitani, Seiya Nishiyama, Kentaro Fukano, Keika Miyazawa, Asuka Kitajima, Ikumi Sawada, Yuji Otsuka, Masamitsu Sanui   +9 more
doaj   +1 more source

Impact of Prophylactic Weight-Based Phenylephrine Infusion on Shivering During Cesarean Delivery– A Prospective Randomized Controlled Trial

Journal of Obstetric Anaesthesia and Critical Care
Background: Shivering during cesarean delivery under spinal anesthesia is an undesirable complication. Intravenous phenylephrine infusion, at varying doses, decreases the intensity of redistribution hypothermia with no consensus on ideal dosing regimen ...
Abi V. Prabu, Akilandeswari Manickam, Aruna Parameswari   +2 more
doaj   +1 more source

TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel [PDF]

, 2014
Transient receptor potential (TRP) channels, a superfamily of ion channels, can be divided into 7 subfamilies, including TRPV, TRPC, TRPP, and 4 others. Functional TRP channels are tetrameric complexes consisting of 4 pore-forming subunits.
Birnbaumer, Lutz, Du, Juan, Huang, Yu, Ma, Xin, Shen, Bing, Yao, Xiaoqiang   +5 more
core   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats

Brazilian Journal of Medical and Biological Research, 2001
Ouabain increases vascular resistance and may induce hypertension by inhibiting the Na+ pump. The effects of 0.18 and 18 µg/kg, and 1.8 mg/kg ouabain pretreatment on the phenylephrine (PHE; 0.1, 0.25 and 0.5 µg, in bolus)-evoked pressor responses were ...
L.V. Rossoni, V.D. Pinto, D.V. Vassallo
doaj   +1 more source

Clinical comparison of prophylactic phenylephrine infusion vs. bolus regimens on maternal hemodynamics and neonatal outcomes during cesarean section

Journal of Obstetric Anaesthesia and Critical Care, 2020
Background and Objective: Phenylephrine bolus or infusion is used to maintain arterial blood pressure during the subarachnoid block (SAB) for cesarean section.
Nitesh Kumar, Mathews Jacob, Priya Taank, Shalendra Singh, Neetika Tripathi   +4 more
doaj   +1 more source

A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro" [PDF]

, 2016
The progression of prostate cancer (PC) to a metastatic hormone refractory disease is the major contributor to the overall cancer mortality in men, mainly because the conventional therapies are generally ineffective at this stage. Thus, other therapeutic
Bolchi, Cristiano, Castelnovo, Luca, Colciago, Alessandra, FERRI, NICOLA, Fumagalli, Laura, Mornati, Ornella, Negri Cesi, Paola, Pallavicini, Marco, Valoti, Ermanno   +8 more
core   +2 more sources

Permanent tracheostomy meets 3D‐printing: Surgical technique and innovation

Equine Veterinary Education, EarlyView.
Summary This clinical commentary serves to accompany the recent case report from Debald et al. (2025) detailing the use of a removable, custom, 3D‐printed implant to manage a dynamically collapsing, permanent tracheal stoma. This creative use of an increasingly common technology provided a cost‐effective manner to successfully manage the complications ...
D. Major
wiley   +1 more source