Results 41 to 50 of about 49,790 (238)

Phenylephrine preconditioning of isolated ventricular myocytes involves modulation of KATP channels through activation of survival kinases

open access: yes, 2009
Pretreatment with the α1-adrenoceptor agonist phenylephrine has been shown to protect cardiac tissue from a subsequent period of ischaemia. This phenomenon, known as pharmacological preconditioning, decreases infarct size and increases the functional ...
Helen Elizabeth Turrell (7595408)
core   +7 more sources

Phenylephrine and the risk of atrial fibrillation in critically ill patients: a multi-centre study from eICU database

open access: yesFrontiers in Pharmacology
BackgroundVasopressors are vital for maintaining blood pressure in critically ill patients, though they carry risks like irregular heartbeats and impaired cardiac oxygen balance.
ZhiMing Huang   +4 more
doaj   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang   +5 more
wiley   +1 more source

Arterial load was acutely increased by phenylephrine intravenous administration.

open access: yes, 2013
A: Real time recording of series of pressure-volume loops during phenylephrine injection by Millar conductance catheter. The mean systolic peak pressure (B) and the mean arterial load (Ea) (C) of 10 mice were calculated before phenylephrine injection ...
Douglas F. Larson (400295)   +2 more
core   +1 more source

Non‐Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In‐Hospital Mortality Risk in Sepsis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study evaluated the association between estimated plasma volume status (ePVS) and in‐hospital mortality in adult patients with sepsis from the MIMIC‐IV (v2.2) database. After excluding patients with early death, readmission, red blood cell transfusion, malignancy, or missing ePVS data, 17,403 patients meeting Sepsis‐3
Zhi‐An Si   +3 more
wiley   +1 more source

Comparison of Bolus Phenylephrine, Ephedrine and Mephentermine for Maintenance of Arterial Pressure during Spinal Anesth

open access: yesJournal of Nepal Medical Association, 2010
INTRODUCTION: Hypotension is common following spinal anesthesia. Various vasopressors have been indicated to prevent it. The study compares three such agents namely phenylephrine, ephedrine and mephentermine. METHODS: The study included 90 patients
B Bhattarai, S Y Bhat, M Upadya
doaj   +1 more source

Inflammation contributes to axon reflex vasodilatation evoked by iontophoresis of an alpha-1 adrenoceptor agonist [PDF]

open access: yes, 2011
Iontophoresis of aradrenoceptor agonists in the human forearm evoke axon reflex vasodilatation, possibly due to an accumulation of inflammatory agents at the site of iontophoresis.
Drummond, P.D.
core  

Distribution of the characteristics of the study population by groups, intervention (tranexamic acid plus phenylephrine) versus control (phenylephrine alone).

open access: yes, 2014
Distribution of the characteristics of the study population by groups, intervention (tranexamic acid plus phenylephrine) versus control (phenylephrine alone).
Jalal Poorolajal (295323)   +6 more
core   +1 more source

How I Do It: A Novel Case Series of Office‐Based Laser Complete Excision of Vocal Fold Cysts

open access: yesThe Laryngoscope, EarlyView.
Office‐based complete excision of vocal fold cysts using Trublue laser via transnasal flexible endoscopy is a technically feasible alternative to conventional marsupialization, enabling en bloc removal under local anesthesia with excellent procedural tolerability.
Aurora Ka Yue Tam   +5 more
wiley   +1 more source

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