Results 41 to 50 of about 36,919 (181)

PROPHYLACTIC PHENYLEPHRINE INFUSION VERSUS RESCUE BOLUSES: EFFECT ON THE PHYSICIAN INTERVENTION AND FLUID ADMINISTRATION

open access: yesPakistan Armed Forces Medical Journal, 2018
Objective: To compare the effect of prophylactic phenylephrine infusion on the fluid management and physician intervention as compared with rescue boluses of phenylephrine alone. Study Design: Randomized controlled trial.
Saira Mahboob, Ahmed Mujadid Burki
doaj   +2 more sources

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Particle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs

open access: yesInternational Journal of Nanomedicine, 2011
Shasha Rao, Yunmei Song, Frank Peddie, Allan M EvansSansom Institute for Health Research, Division of Health Sciences, University of South Australia, Adelaide, South Australia, AustraliaAbstract: Poorly water-soluble drugs, such as phenylephrine, offer ...
Rao S, Song Y, Peddie F, Evans AM
doaj  

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

open access: yesCell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu   +5 more
wiley   +1 more source

Complications and outcomes of standing flank versus ventral midline laparotomy for equine nephrosplenic entrapment

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Nephrosplenic entrapment (NSE) is a common surgical colic in horses. Ventral midline laparotomy (VML) under general anaesthesia (GA) is the standard approach, whereas standing flank laparotomy (SFL) is an alternative approach for surgical correction. However, direct comparisons between these approaches are lacking.
V. Santalucia   +5 more
wiley   +1 more source

Retinal Artery Contraction After Phenylephrine as a Cardiovascular Risk Biomarker

open access: yesClinical Ophthalmology, 2020
Alfonso Casado, Alicia López-de-Eguileta, Soraya Fonseca, Andrea Cerveró, Jorge Gaitán Department of Ophthalmology, Hospital Universitario Marqués de Valdecilla, Santander, SpainCorrespondence: Jorge GaitánOphthalmology
Casado A   +4 more
doaj  

Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats

open access: yesBrazilian Journal of Medical and Biological Research, 2001
Ouabain increases vascular resistance and may induce hypertension by inhibiting the Na+ pump. The effects of 0.18 and 18 µg/kg, and 1.8 mg/kg ouabain pretreatment on the phenylephrine (PHE; 0.1, 0.25 and 0.5 µg, in bolus)-evoked pressor responses were ...
L.V. Rossoni, V.D. Pinto, D.V. Vassallo
doaj   +1 more source

Clinical comparison of prophylactic phenylephrine infusion vs. bolus regimens on maternal hemodynamics and neonatal outcomes during cesarean section

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2020
Background and Objective: Phenylephrine bolus or infusion is used to maintain arterial blood pressure during the subarachnoid block (SAB) for cesarean section.
Nitesh Kumar   +4 more
doaj   +1 more source

Surgical management of an odontogenic collision tumour and oronasal fistula in a 14‐year‐old Warmblood mare

open access: yesEquine Veterinary Education, EarlyView.
Summary Tumours of the equine nasal passages and paranasal sinuses are uncommon, and collision tumours, two independent neoplasms arising adjacently, are exceptionally rare. Cementomas and osteolipomas are both benign, slow‐growing tumour types, but are only sparsely described in horses.
E. Stas   +3 more
wiley   +1 more source

Timing of intrapartum transfusion among obstetric patients, stratified by admission and discharge haemoglobin, relative to anaesthesia care: A retrospective cohort study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background We previously validated and implemented criteria for auditing anaesthesiologists with intraoperative transfusion based on low median blood loss of the surgical procedure or absence of anaemia before transfusion. However, obstetrical cases were excluded during implementation, as the peripartum blood management protocol does not ...
Franklin Dexter   +2 more
wiley   +1 more source

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