Results 31 to 40 of about 36,780 (188)

Patient‐reported outcomes and visual function after four refractive strategies in cataract surgery: A randomized controlled trial

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate patient‐reported outcome measures (PROMs) and visual function across four groups of public cataract patients: emmetropia, mini‐monovision, monovision with partial‐range of field (RoF) narrow intraocular lenses (IOLs) and patients implanted with partial‐RoF extended IOLs.
Anne Guldhammer Skov, Morten la Cour, Birgitte Moldow, Lars Holm, Therese Krarup   +4 more
wiley   +1 more source

Comparing the effect of hypotension treatment due to spinal anesthesia with ephedrine or phenylephrine on arterial blood gases and neonatal Apgar score during cesarean delivery in obese mothers: randomized clinical trial [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019
Introduction: Hypertension in obese patients is more affected by spinal anesthesia than normal people. Due to the lack of study and recommendation of articles about comparison of ephedrine and phenylephrine in obese patients during cesarean section, this
Solmaz Fakhari, Iesa Bile Jani, Simin Atashkhouei, Mehdi Khanbabayi Gol, Safa Soliemanzadeh   +4 more
doaj   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Prediction of preload dependency using phenylephrine-induced peripheral perfusion index during general anaesthesia: a prospective observational study

BMC Anesthesiology
Background Tracking preload dependency non-invasively to maintain adequate tissue perfusion in the perioperative period can be challenging.The effect of phenylephrine on stroke volume is dependent upon preload.
Yusuke Iizuka, Koichi Yoshinaga, Shizuka Amitani, Seiya Nishiyama, Kentaro Fukano, Keika Miyazawa, Asuka Kitajima, Ikumi Sawada, Yuji Otsuka, Masamitsu Sanui   +9 more
doaj   +1 more source

Impact of Prophylactic Weight-Based Phenylephrine Infusion on Shivering During Cesarean Delivery– A Prospective Randomized Controlled Trial

Journal of Obstetric Anaesthesia and Critical Care
Background: Shivering during cesarean delivery under spinal anesthesia is an undesirable complication. Intravenous phenylephrine infusion, at varying doses, decreases the intensity of redistribution hypothermia with no consensus on ideal dosing regimen ...
Abi V. Prabu, Akilandeswari Manickam, Aruna Parameswari   +2 more
doaj   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

Equine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh, C. R. Daniel, J. A. Keen, N. J. Parkinson, B. C. McGorum   +4 more
wiley   +1 more source

Pharmacokinetics of Intramuscular and Intravenous Glycopyrrolate in Juvenile New Zealand White Rabbits

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Glycopyrrolate is an alternative to atropine to treat bradyarrhythmias in anesthetized rabbits; however, there are no pharmacokinetic studies in the literature. Six female New Zealand White rabbits received glycopyrrolate 0.05 mg/kg intravenously (IV) in the cephalic vein or intramuscularly (IM) in a complete crossover design.
Jocelyn Marchiori, Andrea Sanchez, Kristen Messenger, Jennifer M. Reinhart, Hugues Beaufrère, Sonja Fonfara, Alexander Valverde, Yu Gu, Ron Johnson   +8 more
wiley   +1 more source