Results 11 to 20 of about 36,919 (181)

Effect of intravenous phenylephrine infusion on dose requirement of intrathecal plain levobupivacaine for cesarean section: A placebo-controlled preliminary study

Saudi Journal of Anaesthesia, 2017
Background: Phenylephrine infusion has been shown to decrease rostral spread of plain and hyperbaric local anesthetic (LA) when compared to ephedrine infusion.
Asha Tyagi, Aanchal Kakkar, Namrata Niwal, Medha Mohta, Ashok Kumar Sethi   +4 more
doaj   +1 more source

Phenylephrine as an alternative to cocaine for nasal vasoconstriction before nasal surgery: A randomised trial

Indian Journal of Anaesthesia, 2013
Background: Cocaine is often used topically to provide the profound vasoconstriction required for nasal surgery; however, it has been associated with intraoperative cardiac adverse effects.
Sawsan T AlHaddad, Ashish K Khanna, Edward J Mascha, Basem B Abdelmalak   +3 more
doaj   +1 more source

Simultaneous determination of Guaifenesin, codeine phosphate, phenylephrine hydrochloride, and sodium benzoate in syrup pharmaceutical form by RP-HPLC

Al-Kitab Journal for Pure Sciences, 2023
This work describes the development of the RP-HPLC method for the simultaneous estimation of Guaifenesin, codeine phosphate, phenylephrine, and sodium benzoate.
Muthana S. Ali, Ali E. Karim, Maiser Z. Mohye, Azza M. Al-metwali, Salah N. Ibrahim   +4 more
doaj   +1 more source

Effect of Phenylephrine on Cerebrovascular Regulation: A Translational Perspective

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Phenylephrine is an alpha 1‐adrenergic receptor (α1R) agonist. Evidence indicates activation of α1Rs can initiate both vasoconstrictor and dilator signaling. How phenylephrine affects cerebrovascular regulation remains unclear.
Adam M. S. Luchkanych, Breanna Barlage, Gabriela Delgado, Jude S. Morton, Cameron J. Morse, Erika M. Boerman, Ryan L. Hoiland, Mypinder S. Sekhon, Michael M. Tymko, Jaume Padilla, Craig A. Emter, Corey R. Tomczak, M. Harold Laughlin, T. Dylan Olver   +13 more
doaj   +1 more source

Comparison of phenylephrine and norepinephrine for prevention of hypotension in patients undergoing cesarean section under spinal anesthesia – A randomized prospective study

Journal of Obstetric Anaesthesia and Critical Care, 2022
Background: Hypotension is a common side effect of spinal anesthesia for cesarean section with incidence of upto 71%. Various vasopressors are available for counteracting spinal hypotension each with different pharmacological profile.
Wakhloo Renu, Bhagat Heena, Gandotra Megha, Suri Era   +3 more
doaj   +1 more source

Prophylactic Phenylephrine Increases the Dose Requirement of Oxytocin to Treat Uterine Atony During Cesarean Delivery: A Double-Blinded, Single-Center, Randomized and Placebo-Controlled Trial

Frontiers in Pharmacology, 2021
Purpose: Studies involving mouse models and human uterine smooth muscle cells have shown that phenylephrine inhibits uterine contractions in non-pregnant mice and human in vitro cell via cyclic adenosine monophosphate (cAMP) signaling. However, there has
Yao-Hua Shen, Fan Yang, Li-Dan Jin, Yu-Jia Qian, Li Xing, Ya-Li Huang, Su-Feng Lin, Fei Xiao   +7 more
doaj   +1 more source

Tachycardia as Indication for Prophylactic Phenylephrine in Caesarean Section under Spinal Anesthesia: An Observational Study Tachycardia as Indication for Prophylactic Phenylephrine in C.S. by Spinal Anesthesia [PDF]

Ain Shams Medical Journal
Background: During cesarean section (CS), spinal anesthesia has some side effects like hypotension, which may affect both the mother and fetus. Vomiting, lightheadedness and nausea can result from decrease in blood pressure.
SHERIF Shabaan, MAHA EL DERH, SAMAR Abdel Twab   +2 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Comparison of Metaraminol, Phenylephrine, and Norepinephrine Infusion for Prevention of Hypotension During Combined Spinal-Epidural Anaesthesia for Elective Caesarean Section: A Three-Arm, Randomized, Double-Blind, Non-Inferiority Trial

Drug Design, Development and Therapy, 2022
Youfa Zhou,1,* Yunyun Yu,1,2,* Miaofei Chu,1,3 Yanting Zhang,1 Xin Yu,1 Gang Chen1 1Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Zhou Y, Yu Y, Chu M, Zhang Y, Yu X, Chen G   +5 more
doaj  

Efficacy of fixed-dose phenylephrine bolus for treating post-spinal hypotension: Comparison between pre-eclamptics and normotensives

Journal of Anaesthesiology Clinical Pharmacology, 2023
Background and Aims: Pre-eclamptic parturients may have an exaggerated response to vasopressors. This study compares the efficacy of a 50 μg fixed bolus of phenylephrine for treatment of post-spinal hypotension in pre-eclamptic versus normotensive ...
Rashmi Salhotra, Asha Tyagi, Rajesh Singh Rautela, Jainendra Chauhan, Lhamo Dolma, Ankit Sharma, Prerna Batra, Himsweta Srivastava   +7 more
doaj   +1 more source