Results 11 to 20 of about 61,478 (225)

Postsynaptic α1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition [PDF]

, 2016
BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS).
Medow, MS, Merchant, S, Stewart, JM, Suggs, M, Sutton, R, Terilli, C, Visintainer, P   +6 more
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A comparative study on the effect of dopamine vs phenylephrine in improving the cutaneous analgesic effect of mexiletine in rats

Perioperative Medicine, 2023
Background The present study aimed to compare the effects of the combined administration of two adjuvants, dopamine and phenylephrine, on the cutaneous analgesic effect and duration of mexiletine in rats. Methods Nociceptive blockage was evaluated by the
Kesong Zheng, Mingming Han, Fang Kang, Chengwei Yang, Juan Li   +4 more
doaj   +1 more source

Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate [PDF]

, 2011
Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction.
Anglin IE, Boris Schlenker, Chang L, Chon JK, Christ GJ, Christian G. Stief, Christian Gratzke, Erdogru T, Frank Strittmatter, Glassman DT, Golomb E, Johanna Göttinger, Kanagawa K, Karl-Erik Andersson, Kyprianou N, Kyprianou N, Kyprianou N, Lucia MS, Luthin GR, Marinese D, Maroni PD, Martin Hennenberg, McCubrey JA, McVary KT, Michel MC, Oliver Reich, Petter Hedlund, Ricarda M. Bauer, Roehrborn CG, Roehrborn CG, Royuela M, Royuela M, Schilit S, Schwinn DA, Shimada K, Srinivasan D, Turkeri LN, Xiao L, Zhang H, Zhang Z   +39 more
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Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]

, 2011
Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin, Kunuthur, S. P., Milliken, P. H., Suckling, C. J., Wadsworth, R. M.   +4 more
core   +1 more source

Application of Racemization Process to Dynamic Resolution of ()-Phenylephrine to ()-Phenylephrine β-D-Glucoside by Glucosyltransferase

Natural Product Communications, 2018
Enzymatic glucosylation of racemic phenylephrine by glucosyltransferase from Nicotiana tabacum gave ( R )-phenylephrine glucoside and recovered ( S )-phenylephrine.
Yuya Fujitaka, Daisuke Uesugi, Hatsuyuki Hamada, Hiroki Hamada, Kei Shimoda, Masayoshi Yanagi, Manami Inoue, Shin-ichi Ozaki   +7 more
doaj   +1 more source

Alpha1 -adrenergic stimulation selectively enhances endothelium-mediated vasodilation in rat cremaster arteries. [PDF]

, 2018
We have systematically investigated how vascular smooth muscle α1 -adrenoceptor activation impacts endothelium-mediated vasodilation in isolated, myogenically active, rat cremaster muscle 1A arteries.
Braun, Andrew P, Davis, Michael J, Hill, Michael A, Mishra, Ramesh C, Rahman, Mohammad M, Wulff, Heike   +5 more
core   +1 more source

Effect of intravenous phenylephrine infusion on dose requirement of intrathecal plain levobupivacaine for cesarean section: A placebo-controlled preliminary study

Saudi Journal of Anaesthesia, 2017
Background: Phenylephrine infusion has been shown to decrease rostral spread of plain and hyperbaric local anesthetic (LA) when compared to ephedrine infusion.
Asha Tyagi, Aanchal Kakkar, Namrata Niwal, Medha Mohta, Ashok Kumar Sethi   +4 more
doaj   +1 more source

Inhibition of histone deacetylase as a treatment for cardiac hypertrophy [PDF]

, 2005
The present invention provides for methods of treating and preventing cardiac hypertrophy. Class II HDACs, which are known to participate in regulation of chromatin structure and gene expression, have been shown to have beneficial effects on cardiac ...
Bristow, Michael R., Long, Carlin, McKinsey, Timothy A., Olson, Eric N.   +3 more
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Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition [PDF]

, 2008
Inhibition of glycogen synthase kinase 3β (GSK3β) as a consequence of its phosphorylation by protein kinase B/Akt (PKB/Akt) has been implicated in cardiac myocyte hypertrophy in response to endothelin-1 or phenylephrine.
Alsafi, Ali, Clerk, Angela, Cullingford, Timothy E., Fuller, Stephen John, Giraldo Ramirez, Alejandro, Markou, Thomais, Sugden, Peter H., Weiss, Sophie C.   +7 more
core   +1 more source

Simultaneous determination of Guaifenesin, codeine phosphate, phenylephrine hydrochloride, and sodium benzoate in syrup pharmaceutical form by RP-HPLC

Al-Kitab Journal for Pure Sciences, 2023
This work describes the development of the RP-HPLC method for the simultaneous estimation of Guaifenesin, codeine phosphate, phenylephrine, and sodium benzoate.
Muthana S. Ali, Ali E. Karim, Maiser Z. Mohye, Azza M. Al-metwali, Salah N. Ibrahim   +4 more
doaj   +1 more source