Results 71 to 80 of about 66,688 (258)

Prediction of preload dependency using phenylephrine-induced peripheral perfusion index during general anaesthesia: a prospective observational study

BMC Anesthesiology
Background Tracking preload dependency non-invasively to maintain adequate tissue perfusion in the perioperative period can be challenging.The effect of phenylephrine on stroke volume is dependent upon preload.
Yusuke Iizuka, Koichi Yoshinaga, Shizuka Amitani, Seiya Nishiyama, Kentaro Fukano, Keika Miyazawa, Asuka Kitajima, Ikumi Sawada, Yuji Otsuka, Masamitsu Sanui   +9 more
doaj   +1 more source

Comparing Topical Mydriatics Effectiveness in Preserving Pupil Dilation during Small-incision Cataract Surgery

Journal of Pharmaceutical Research
Background: Pupil dilation using topical mydriatics is one of the important pre-requisites prior to performing cataract surgery. There are various mechanisms through which mydriasis can be achieved.
Aastha Shukla, Vikas Kamat, Pramod Wartha, Milind Sonone   +3 more
doaj   +1 more source

Alpha1 -adrenergic stimulation selectively enhances endothelium-mediated vasodilation in rat cremaster arteries. [PDF]

, 2018
We have systematically investigated how vascular smooth muscle α1 -adrenoceptor activation impacts endothelium-mediated vasodilation in isolated, myogenically active, rat cremaster muscle 1A arteries.
Braun, Andrew P, Davis, Michael J, Hill, Michael A, Mishra, Ramesh C, Rahman, Mohammad M, Wulff, Heike   +5 more
core   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

A NEW MODEL OF TRANSIENT ISCHEMIA OF RABBIT EYES AND A QUANTITATIVE ASSESSMENT OF ISCHEMIA DEGREE USING OPHTHALMOPLETHYSMOGRAPHY

Российский офтальмологический журнал, 2018
Purpose: to create a model of transient eye ischemia in order to study the effectiveness of drugs affecting the intensity of ocular blood flow in ischemic conditions, and to develop a method of quantifying the extent of ischemia.
N. B. Chesnokova, A. V. Grigoryev, K. N. Mustafayeva, O. V. Beznos   +3 more
doaj   +1 more source

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

British Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu, Yanyan Zhang, Meiling Shan, Jiaqi Cao, Zihan Fan, Zhaoxia Xu, Xiaozhen Ding, Xiaodong Liu, Lijun Shi   +8 more
wiley   +1 more source

Latanoprost with high precision, piezo-print microdose delivery for IOP lowering: clinical results of the PG21 study of 0.4 µg daily microdose. [PDF]

, 2018
Background:Topical high-precision piezo-print delivery of microdoses of latanoprost achieved significant IOP reduction consistent with the eyedropper effect but with a 75% reduced exposure to drugs and preservatives.
Ianchulev, Tsontcho, Kramm, Robert L, Lin, Shan, Pasquale, Louis R, Tsai, James C, Weinreb, Robert N   +5 more
core  

TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel [PDF]

, 2014
Transient receptor potential (TRP) channels, a superfamily of ion channels, can be divided into 7 subfamilies, including TRPV, TRPC, TRPP, and 4 others. Functional TRP channels are tetrameric complexes consisting of 4 pore-forming subunits.
Birnbaumer, Lutz, Du, Juan, Huang, Yu, Ma, Xin, Shen, Bing, Yao, Xiaoqiang   +5 more
core   +1 more source

Bilateral laryngeal paralysis (aplegia) occurring late during the recovery of a horse after orthopaedic surgery

Equine Veterinary Education, EarlyView.
Summary A 9‐year‐old male castrated Standardbred was presented for evaluation of a comminuted right front first phalanx fracture. On initial clinical examination, mild haemoconcentration and increased vital parameters were noted. After overnight hospitalisation, the horse underwent general anaesthesia for surgical fracture repair.
I. Lutvikadic, K. Hopster, B. Driessen
wiley   +1 more source

Effect of heat exposure on viability and contractility of cultured prostatic stromal cells [PDF]

, 2000
Objectives: Different thermotherapeutic modalities such as transurethral microwave therapy or transurethral needle ablation have been developed to provide effective alternatives to surgical management of benign prostate hyperplasia (BPH).
Bartsch, Georg, Boesch, Simone, Corvin, Stefan, Klocker, Helmut, Maneschg, Christoph, Radmayr, Christian   +5 more
core   +1 more source