Compatibility study of paracetamol, chlorpheniramine maleate and phenylephrine hydrochloride in physical mixtures [PDF]
Saudi Pharmaceutical Journal, 2017 Paracetamol (PAR), phenylephrine hydrochloride (PHE) and chlorpheniramine maleate (CPM) are commonly used in clinical practice as antipyretic and analgesic drugs to ameliorate pain and fever in cold and flu conditions.
Kahynna Cavalcante Loureiro +2 more
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Revisiting the impact of phenylephrine hydrochloride on static and dynamic accommodation
Indian Journal of Ophthalmology, 2012 Purpose: Phenylephrine hydrochloride (PHCl), a commonly used mydriatic agent, causes a small but significant deterioration of accommodation. The relative roles of pharmacology and optics in this deterioration, however, remain unascertained.
Samrat Sarkar +2 more
doaj +5 more sources
An alternative synthesis of (±)-phenylephrine hydrochloride [PDF]
Maejo International Journal of Science and Technology, 2014 This study presents alternative synthetic pathways and reagents for the preparation of racemic phenylephrine hydrochloride. Using m-hydroxybenzaldehyde as starting material, two separate pathways–epoxidation and bromohydrin formation–are
Aphiwat Teerawutgulrag +3 more
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Optimization of HPLC methods for the development of quality control methods of combined powder formulations with paracetamol, phenylephrine hydrochloride, pheniramine maleate [PDF]
BMC ChemistryOur main goal was to optimize HPLC methods for the determination of a combined powder containing paracetamol, phenylephrine hydrochloride, and pheniramine maleate based on the indicators «Quantitative determination», «Uniformity of dosage units», and «4 ...
Oleksandra Havrylenko +4 more
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Voltammetric determination of phenylephrine hydrochloride using a multi-walled carbon nanotube-modified carbon paste electrode [PDF]
Royal Society Open Science, 2018 A chemically modified carbon paste electrode (CPE) was designed by mixing graphite and multi-walled carbon nanotubes (MWCNT). The electrochemical behaviour was studied, and the determination method of phenylephrine hydrochloride (PHE) on this sensor was ...
exaly +3 more sources
Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed-Dose Combination Tablets in Healthy Chinese Volunteers. [PDF]
Clin Pharmacol Drug DevAbstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Ye M +8 more
europepmc +2 more sources
مجلة بغداد للعلوم, 2015 A spectrophotometric method has been proposed for the determination of two drugs containing phenol group [phenylephrine hydrochloride (PHP) and salbutamol sulphate (SLB)] in pharmaceutical dosage forms.
Baghdad Science Journal
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BMC Chemistry, 2023 The development and validation of the stability indicating HPLC technique has contributed to the understanding of the stability profile of ibuprofen (IBU) and phenylephrine (PHE). Stability profile was achieved for PHE; the drug was found to be liable to
Khadiga M. Kelani +4 more
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Synephrine potentiates lidocaine-induced cutaneous analgesia via α-adrenergic receptors in male rats. [PDF]
Physiol RepThe enhanced analgesic effects of lidocaine–synephrine or lidocaine–phenylephrine combinations are mediated via α‐adrenergic receptor activation. Abstract This study aimed to assess the cutaneous analgesic effect of the lidocaine–synephrine combination and its underlying α‐adrenergic receptor‐mediated mechanism in comparison with phenylephrine ...
Chou AK +5 more
europepmc +2 more sources
Hypromellose improves mydriasis dynamics by phenylephrine in a rabbit experimental model
Российский офтальмологический журнал, 2023 Purpose: to determine the main characteristics of the mydriatic effect of drug formulations of phenylephrine, containing and not containing hypromellose, hyaluronic acid as an auxiliary component, in a comparative in vivo study, as well as to study their
E. V. Blinova +7 more
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