It was established that methemoglobiemia in experimental rats induced by one intraperitoneal injection of phenylhydrazine chloride (DL50), for a long time (up to 21 days after the injection of the drug) is accompanied by disorders in functional ...
I. A. Shprling +6 more
doaj +2 more sources
Hematopoietic effect of echinochrome on phenylhydrazine-induced hemolytic anemia in rats [PDF]
Background Hemolytic anemia (HA) is a serious health condition resulting from reduced erythrocytes’ average life span. Echinochrome (Ech) is a dark-red pigment found in shells and spines of sea urchins.
Mona S. E. F. El-Shehry +11 more
doaj +3 more sources
Glutathione status in the blood of rats after reticulocytosis induced by phenylhydrazine and bleeding [PDF]
In this experiment, we compared the in vivo effects of phenylhydrazine (PHZ) and bleeding treatment on the redox status and glutathione antioxidative mechanism parameters in the plasma and red blood cells (RBC) of rats.
Marković Snežana D. +6 more
doaj +3 more sources
Elevated Levels of Gonadotrophic Hormones and Antioxidant Biomarker in Male Rats Following Administration of Hydromethanol Leaf Extract of Justicia secunda in Response to 2,4-Dinitrophenylhydrazine Induction [PDF]
Background: 2,4-Dinitrophenylhydrazine induces testicular toxicity and can result in reproductive dysfunction in male rats. Aim: This study investigated the effects of hydromethanolic leaf extract of Justicia secunda on phenylhydrazine (PHZ)-induced ...
Samuel Kelechi Mobisson +5 more
doaj +2 more sources
Targeting anemia-induced CD71+ reticulocytes protects mice from Plasmodium infection [PDF]
Malaria, caused by Plasmodium spp., is a global health concern linked to anemia and increased mortality. Compensatory erythropoiesis seen during acute anemia results in an increased circulating reticulocyte count (i.e., immature RBC), a key factor in ...
Sareh Zeydabadinejad +8 more
doaj +2 more sources
(E)-1-(2-Nitrobenzylidene)-2-phenylhydrazine
The asymmetric unit of the title compound, C13H11N3O2, contains two molecules with slightly different conformations: the dihedral angle between the aromatic rings is 13.01 (10)° in one molecule and 14.05 (10)° in the
Hazoor Ahmad Shad +4 more
doaj +2 more sources
The hematopoietic potential of methanolic and aqueous extracts of Portulaca oleracea in a phenylhydrazine model of anemia [PDF]
Objective: Portulaca oleracea, commonly known as Purslane, is traditionally used as a sour, diuretic, and cooling herb with hemostatic properties. The present study evaluates the antianemic effect of methanolic and aqueous extracts of P.
Kobra Shirani +4 more
doaj +1 more source
Brassica nigra has been reported to possess antioxidant activity, anti-inflammatory activity, anti-epileptic activity, antidiabetic activity, anthelminthic activity, nephroprotective activity and hepatoprotective activity.
E. Obayuwana, M. O. Obayuwana
doaj +1 more source
Possible role of pomegranate fruit in reversing renal damage in rats exposed to Phenylhydrazine
Background: Pomegranate granatum (molasses and peels) and its constituents showed protective effects against natural toxins such as phenylhydrazine as well as chemical toxicants as arsenic, diazinon, and carbon tetrachloride.
Nabil Abbas Soliman +4 more
doaj +1 more source
Moringa oleifera has been shown to have a variety of medicinal benefits, including hepatoprotective effects. Phenylhydrazine has been used to cause hepatotoxicity in experimental models.
E. Obayuwana +7 more
doaj +1 more source

