Results 41 to 50 of about 18,205 (203)

Studies on erythropoiesis 1. Studies on cell size of erythroid cells from anemic animal [PDF]

open access: yes, 1964
For the purpose to look into the regulatory mechanism of erythropoiesis, changes in the cell volume and the cell size of the erythroid cells have been observed in peripheral blood and marrow from normal and phenylhydrazine induced anemic rabbits. And the
Shibata, Takashi
core   +1 more source

Studies on the relation between heme and nucleic acid syntheses in erythroid cell. I. Effects of aminopterin and bromouracil on hemopoiesis and hemoglobin synthesis in anemic rat [PDF]

open access: yes, 1968
For the purpose to see how the suppression of the nucleic acid synthesis disturbs the cell specialization process the author observed the erythroid cell specialization in anemic rats by treating them with aminopterin (AP) and 5-bromouracil (BU).
Shigehisa, Morio
core   +1 more source

Development of reverse-transcription PCR techniques to analyse the density and sex ratio of gametocytes in genetically diverse Plasmodium chabaudi infections [PDF]

open access: yes, 2007
We have developed cross-genotype and genotype-specific quantitative reverse-transcription PCR (qRT-PCR) assays to detect and quantify the number of parasites, transmission stages (gametocytes) and male gametocytes in blood stage Plasmodium chabaudi ...
Abdel-Wahab   +44 more
core   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade   +4 more
wiley   +1 more source

Studies on the DNA metabolism of erythroid cell. II. Decrease in DNA contents and DNA synthetic rate during erythroid cell specialization [PDF]

open access: yes, 1970
For the purpo3e to determine exactly what stage of cell specialization the DNA level of erythroid cell nuclei begins to decline, the author observed the DNA level of erythroblasts in mitosis by microspectrophotometry and the DNA synthesis by flash ...
Inoue, Masanao
core   +1 more source

Postsynthetic Modifications of Amide‐Enaminone‐Based [2]Rotaxanes for the Stereocontrolled Synthesis of Functionalized β‐Lactams

open access: yesChemistryEurope, EarlyView.
Novel amido‐enaminone threads efficiently template the formation of hydrogen‐bonded [2]rotaxanes and enable diverse postsynthetic modifications. Benzyl groups promote diastereoselective cyclizations to interlocked lactams while the enaminone motif allows stopper exchange while preserving the mechanical bond.
Syed S. Razi   +4 more
wiley   +1 more source

Impact of C18 Epimerization of Indole‐ and Pyrazole‐Fused 18β‐Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies

open access: yesChemMedChem, EarlyView.
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez   +10 more
wiley   +1 more source

Expression of ABCG2 (BCRP) in mouse models with enhanced erythropoiesis

open access: yesFrontiers in Pharmacology, 2014
Haem is a structural component of numerous cellular proteins which contributes significantly to iron metabolic processes in mammals but its toxicity demands that cellular levels must be tightly regulated. Breast Cancer Resistance Protein (BCRP/ABCG2), an
Gladys Oluyemisi Latunde-Dada   +4 more
doaj   +1 more source

A Study on Proteolytic Enzyme Activity in the Erythrocytes of Diabetic Patients [PDF]

open access: yes, 2011
The present study demonstrates the possibility of increased proteolytic activities in diabetic individuals. Proteolytic activity was measured by the amount of amino group released by the erythrocyte lysate of the diabetic individual using phenylhydrazine
Bhat, Gopalakrishna P, BS, Varashree
core  

Home - About - Disclaimer - Privacy