Results 91 to 100 of about 32,659 (306)

Carbohydrate status in patients with phenylketonuria

Orphanet Journal of Rare Diseases, 2018
BackgroundIn patients with phenylketonuria (PKU), a low-phenylalanine (Phe) diet supplemented with low-protein foods and a Phe-free amino acid mixture favors a dietary intake rich in carbohydrates, but little is known about how these molecules are ...
M. Couce, Paula Sánchez-Pintos, I. Vitoria, M. D. de Castro, L. Aldámiz-Echevarría, Patricia Correcher, A. Fernández‐Marmiesse, Iria Roca, A. Hermida, M. Martínez-Olmos, R. Leis   +10 more
semanticscholar   +1 more source

Rapid one-step separation and purification of recombinant phenylalanine dehydrogenase in aqueous two-phase systems [PDF]

, 2008
Background: Phenylalanine dehydrogenase (PheDH; EC 1.4.1.20) is a NAD +-dependent enzyme that performs the reversible oxidative deamination of L-phenylalanine to phenylpyruvate.
Mohammadi, H.S., Omidinia, E., Taherkhani, H.   +2 more
core  

Evidence of Oxidative Stress and Secondary Mitochondrial Dysfunction in Metabolic and Non-Metabolic Disorders [PDF]

, 2017
: Mitochondrial dysfunction and oxidative stress have been implicated in the pathogenesis of a number of diseases and conditions. Oxidative stress occurs once the antioxidant defenses of the body become overwhelmed and are no longer able to detoxify ...
Angermuller, Artuch, Brismar, Calabresi, Carre, Duarte, El-Bassyouni, Fenton, Hayashi, Krahenbuhl, Lindblad, Manoli, Manoli, Martin, McMurry, Moser, Reza Rezvani, Royes, Schrakamp, Scriver, Taneka, Trinh, Van Bakel, Velema, Wilke, Williams   +25 more
core   +1 more source

PET/NIR‐II fluorescence imaging and image‐guided surgery of breast cancer using a CD47‐specific nanobody

VIEW, EarlyView.
A CD47‐targeted dual‐modal imaging probe combining positron emission tomography and second near‐infrared fluorescence enables precise preoperative tumor localization and intraoperative guidance for complete resection of breast cancer lesions, including metastases, offering a promising strategy to enhance surgical accuracy and improve clinical outcomes.
Jun Li, Runge Zhao, Jinyuan Zhang, Zixuan Huang, Xiaoyan Wang, Rui Zhang, Chenghui Zheng, Mengjie Dong, Yongsheng Zhao, Jing Mu   +9 more
wiley   +1 more source

Breastfeeding Success among Infants with Phenylketonuria [PDF]

, 2012
Breast milk is the nutrition of choice for human infants (American Academy of Pediatrics, 2005; American Association of Family Physicians, 2008; Association of Women’s Health Obstetric and Neonatal Nurses, 2005; Canadian Paediatric Society, 2005; U.S ...
Agostoni, American Academy of Pediatrics, American Association of Family Physicians, Association of Women's Health Obstetric and Neonatal Nurses, Blau, Canadian Paediatric Society, Cornejo, Cummings, de Baulny, Demirkol, Dhondt, Ernest, Forster, Gail M. Houck, Greve, Guthrie, Hoddinott, Horta, Huner, Huner, Huttenlocher, Ip, Janas, Jervis, Kanufre, Kathleen A. Knafl, Kathleen C. Shelton, Kaye, Lonnerdal, Malamud, McCabe, Meyers, Motzfeldt, Nancy D. Lowe, Nayman, Sandra A. Banta-Wright, Scriver, Segev, Therrell, Thulier, U.S. Preventive Services Task Force, van Rijn, World Health Organization, World Health Organization, Zachariassen   +44 more
core   +3 more sources

CHINA’S LAND FINANCE AS ACTIVE MODE OF LAND DEVELOPMENT AND INFRASTRUCTURE DELIVERY: Reality, History and Prospects

International Journal of Urban and Regional Research, EarlyView.
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley   +1 more source

Inhibiting neutral amino acid transport for the treatment of phenylketonuria.

JCI Insight, 2018
The neuropathological effects of phenylketonuria (PKU) stem from the inability of the body to metabolize excess phenylalanine (Phe), resulting in accumulation of Phe in the blood and brain. Since the kidney normally reabsorbs circulating amino acids with
A. Belanger, M. Przybylska, Estelle Gefteas, Matthew Furgerson, S. Geller, A. Kloss, Seng H. Cheng, Yunxiang Zhu, N. Yew   +8 more
semanticscholar   +1 more source

Silencing of juvenile hormone‐related genes through RNA interference leads to molt failure and high mortality in the spongy moth

Insect Science, EarlyView.
The feasibility of using RNA interference to control the globally important quarantine pest, the spongy moth. Targeting genes related to JHs play an important role in the growth and development of insects. First, the open reading frames (ORFs) of Ldjhamt and Ldjheh were identified and characterized, and the target genes were cloned and double‐stranded ...
Wenzhuai Ji, Qing Xie, Xiaoxiao Chang, Juan Shi   +3 more
wiley   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source