Results 101 to 110 of about 16,232 (245)
ABSTRACT The growing recognition of the microbiome’s role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai +6 more
wiley +1 more source
Unrecognized adult phenylketonuria
PKUhttp://dx.doi.org/10.1056/NEJM197308232890803http://dx.doi.org/10.1056 ...
Perry, Thomas L.
core
Phenylketonuria: A Comprehensive Review of Pathophysiology, Diagnosis, and Management Strategies
Introduction: Phenylketonuria (PKU) is a genetically determined congenital metabolic disorder characterized by the body's inability to properly metabolize the amino acid phenylalanine, which is ingested through food.
Agata Konopka +5 more
doaj +1 more source
What Advanced Practice Roles Are Dietitians Undertaking? A Mixed Methods Systematic Review
ABSTRACT Background As health systems globally are facing unprecedented demands, allied health clinicians undertaking advanced practice (AP) roles are increasingly supporting medical professionals, improving health system efficiencies and outcomes. The aim of this mixed methods systematic review was to identify what AP roles dietitians are undertaking ...
Kim Lunardi +2 more
wiley +1 more source
International Survey on Phenylketonuria Newborn Screening
Newborn screening for Phenylketonuria enables early detection and timely treatment with a phenylalanine-restricted diet to prevent severe neurological impairment.
Domen Trampuž +16 more
doaj +1 more source
Estimating Correlations Between Clinical Trial Outcomes Using Generalised Estimating Equations
ABSTRACT Accurately estimating the correlations among clinical trial outcomes is crucial for managing the risk of biopharmaceutical investment portfolios. We propose a novel algorithm for estimating correlations in large clinical trial datasets using a generalised estimating equations (GEE) framework.
Yuehao Dai +4 more
wiley +1 more source
Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla
Aims Major depressive disorder (MDD) is widely considered to be a mood disorder characterized by altered connectivity. The thalamus plays an important role in MDD by connecting large areas of the brain. Here, we explored thalamic connectivity in MDD at the subnuclear level using ultra‐high‐field MRI.
Weijian Liu +10 more
wiley +1 more source
Abstract Ammonia (NH3) is a short‐lived atmospheric pollutant with significant environmental and health impacts. Monitoring NH3 remains challenging, as diurnal variability at local scales is still poorly documented. In this study, we analyze two years (July 2022–June 2024) of NH3 total columns from the Geostationary Interferometric Infrared Sounder ...
Nadir Guendouz +13 more
wiley +1 more source
New era in treatment for phenylketonuria: Pharmacologic therapy with sapropterin dihydrochloride
Cary O HardingDepartments of Molecular and Medical Genetics and Pediatrics, Oregon Health & Science University, Portland, Oregon, USAAbstract: Oral administration of sapropterin hydrochloride, recently approved for use by the US Food and Drug ...
Cary O Harding
core

