Results 91 to 100 of about 16,232 (245)

Investigation of Demographic Indicators of Phenylketonuria Patients and Determining the Reasons for Their Referral to Rehabilitation Centers

open access: yesپزشکی بالینی ابن سینا, 2020
Background and Objective: Phenylketonuria is one of the most common metabolic disorders which causes brain abnormalities in children if they do not receive treatment or their treatment is delayed or ineffective. In this regard, the present study aimed to
Zahra Mortazavi   +4 more
doaj  

Childhood Physical Activity and Developmental Niche in Contemporary Pastoralist Maasai Community in Southern Kenya

open access: yesAmerican Journal of Biological Anthropology, Volume 190, Issue 2, June 2026.
ABSTRACT Objectives Although increasing attention has been directed toward childhood physical activity (PA) in small‐scale societies of the Global South, evidence across the full developmental span remains limited and is often interpreted without sufficient attention to local parental environments, norms, or children's social roles. This study examines
Xiaojie Tian   +3 more
wiley   +1 more source

Screening for Phenylketonuria

open access: yes, 1974
PKU letterhttp://dx.doi.org/10.1136/bmj.1.5896.39-
James, F.E., Winokur, B.
core  

The Effect of Intact Protein from Foods and Phenylalanine Free Medical Foods on Large Neutral Amino Acids in Patients with Phenylketonuria.

open access: yes, 2017
Objective: The primary aim of this retrospective cohort study was to determine the association between the source of dietary protein intake and the sum of plasma concentration of large neutral amino acids (LNAA) in patients with Phenylketonuria (PKU).
Berry, Ann M
core   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1522-1536, June 2026.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra   +4 more
wiley   +1 more source

Specific characteristics of dynamic monitoring of patients diagnosed with classical phenylketonuria during pregnancy

open access: yesЛечащий Врач
Background. The main therapy for phenylketonuria is a specialised diet with restriction of natural protein, respectively phenylalanine with the prescription of specialised therapeutic foods based on amino acids without phenylalanine.
E. A. Shestopalova
doaj   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

open access: yeseFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie   +5 more
wiley   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal   +7 more
wiley   +1 more source

School achievement in pupils with phenylketonuria

open access: yes, 2020
The diploma thesis called "School Achievement in Pupils with Phenylketonuria" tries to outline the lives of people who have to face up to a hereditary metabolic disorder - phenylketonuria, subjective and objective level of school success of these ...
NENADÁLOVÁ, Lucie
core  

Phenylketonuria in the General Population

open access: yes, 1970
Because phenylketonuria was first recognized among severely retarded persons and their families, the finding of elevated serum phenylalanine concentrations has usually been equated with severe mental retardation.
Howell, R. Rodney, R. Rodney Howell
core   +1 more source

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