Results 71 to 80 of about 18,136 (230)

PET/NIR‐II fluorescence imaging and image‐guided surgery of breast cancer using a CD47‐specific nanobody

VIEW, EarlyView.
A CD47‐targeted dual‐modal imaging probe combining positron emission tomography and second near‐infrared fluorescence enables precise preoperative tumor localization and intraoperative guidance for complete resection of breast cancer lesions, including metastases, offering a promising strategy to enhance surgical accuracy and improve clinical outcomes.
Jun Li, Runge Zhao, Jinyuan Zhang, Zixuan Huang, Xiaoyan Wang, Rui Zhang, Chenghui Zheng, Mengjie Dong, Yongsheng Zhao, Jing Mu   +9 more
wiley   +1 more source

Spectrum of Phenylalanine Hydroxylase Gene Mutations in Hamadan and Lorestan Provinces of Iran and Their Associations with Variable Number of Tandem Repeat Alleles

Iranian Journal of Medical Sciences, 2018
Phenylketonuria (PKU) is one of the most common known inherited metabolic diseases. The present study aimed to investigate the status of molecular defects in phenylalanine hydroxylase (PAH) gene in western Iranian PKU patients (predominantly from ...
Reza Alibakhshi, Keivan Moradi, Mostafa Biglari, Samaneh Shafieenia   +3 more
doaj  

CHINA’S LAND FINANCE AS ACTIVE MODE OF LAND DEVELOPMENT AND INFRASTRUCTURE DELIVERY: Reality, History and Prospects

International Journal of Urban and Regional Research, EarlyView.
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley   +1 more source

Psychiatric and Cognitive Aspects of Phenylketonuria: The Limitations of Diet and Promise of New Treatments

Frontiers in Psychiatry, 2019
Phenylketonuria (PKU) is a recessive disorder of phenylalanine metabolism due to mutations in the gene for phenylalanine hydroxylase (PAH). Reduced PAH activity results in significant hyperphenylalaninemia, which leads to alterations in cerebral myelin ...
Killian Ashe, W. Kelso, S. Farrand, J. Panetta, T. Fazio, G. de Jong, M. Walterfang   +6 more
semanticscholar   +1 more source

Global prevalence of classic phenylketonuria based on Neonatal Screening Program Data: systematic review and meta-analysis

Clinical and experimental pediatrics, 2020
Phenylketonuria is a disease caused by congenital defects in phenylalanine metabolism that leads to irreversible nerve cell damage. However, its detection in the early days of life can reduce its severity.
H. Shoraka, A. Haghdoost, M. Baneshi, Z. Bagherinezhad, Farzaneh Zolala   +4 more
semanticscholar   +1 more source

Phenylketonuria screening in Iranian newborns: a systematic review and meta-analysis [PDF]

, 2020
Mehdi Shokri, Parviz Karimi, Hadis Zamanifar, Fatemeh Kazemi, Gholamreza Badfar, Milad Azami   +5 more
openalex   +1 more source

Evolution of the screening program for congenital hypothyroidism and phenylketonuria in Sergipe State from 1995 to 2003 [PDF]

, 2004
Avaliamos o tempo gasto nas diferentes etapas do Programa de Triagem para o Hipotireoidismo Congênito (HC) e Fenilcetonúria (PKU), sua cobertura e a freqüência em Sergipe, de 1998 a 2003, e comparamos com 1995.
Oliveira, Carla Raquel Pereira, Oliveira, Manuel Herminio de Aguiar, Ramalho, Antônio Roberto de Oliveira, Ramalho, Roberto Jose Rabelo   +3 more
core   +1 more source

Silencing of juvenile hormone‐related genes through RNA interference leads to molt failure and high mortality in the spongy moth

Insect Science, EarlyView.
The feasibility of using RNA interference to control the globally important quarantine pest, the spongy moth. Targeting genes related to JHs play an important role in the growth and development of insects. First, the open reading frames (ORFs) of Ldjhamt and Ldjheh were identified and characterized, and the target genes were cloned and double‐stranded ...
Wenzhuai Ji, Qing Xie, Xiaoxiao Chang, Juan Shi   +3 more
wiley   +1 more source

Real‐world comparison of first‐line antiseizure monotherapy and the role of age at treatment initiation in newly diagnosed childhood epilepsy: A cohort study from a tertiary center

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the real‐world effectiveness and tolerability of first‐line antiseizure medication (ASM) monotherapy in children with newly diagnosed epilepsy, focusing on comparative outcomes across developmental age groups and ASM types, and identifying clinical risk factors of treatment failure.
Ningshan Li, Huiting Zhang, Chaoran Yang, Xiaoying Qiao, Dezhi Cao, Lina Men, Guangjun Yu, Jianxiang Liao   +7 more
wiley   +1 more source

FENILCETONÚRIA: UMA REVISÃO DE LITERATURA [PDF]

, 2014
A Fenilcetonúria, causada pela deficiência da enzima fenilalanina hidroxilase e a causa mais frequente de retardo mental, desponta como a mais comum das doenças que envolvem erros congênitos.
Ascenso Rosa, Ruy Roberto Porto, Branco, Alessandra Camillo da Silveira Castello, Silva, Francisco Clenildo Lisboa da   +2 more
core   +1 more source