Results 81 to 90 of about 18,327 (286)

Semisynthetic sensor proteins enable metabolic assays at the point of care

open access: yesScience, 2018
A protein designed to sense metabolites Many diseases cause characteristic changes in blood metabolites. Yu et al. describe a paper-based assay in which a chosen metabolite can be oxidized to generate reduced nicotinamide adenine dinucleotide phosphate ...
Qiuliyang Yu   +9 more
semanticscholar   +1 more source

PET/NIR‐II fluorescence imaging and image‐guided surgery of breast cancer using a CD47‐specific nanobody

open access: yesVIEW, EarlyView.
A CD47‐targeted dual‐modal imaging probe combining positron emission tomography and second near‐infrared fluorescence enables precise preoperative tumor localization and intraoperative guidance for complete resection of breast cancer lesions, including metastases, offering a promising strategy to enhance surgical accuracy and improve clinical outcomes.
Jun Li   +9 more
wiley   +1 more source

The nutritional profiling of special feeds for phenylketonuria [PDF]

open access: yes, 2021
In children with classical phenylketonuria (PKU), a lifelong low phenylalanine diet is the only treatment option with natural protein (phenylalanine) intake restricted to < 20% of safe recommended intake [1] to minimise neurological damage. The diet must
Daly, Anne
core  

Assessment of the impact of phenylketonuria and its treatment on quality of life of patients and parents from seven European countries

open access: yesOrphanet Journal of Rare Diseases, 2015
BackgroundThe strict and demanding dietary treatment and mild cognitive abnormalities seen in PKU treated from a young age can be expected to affect the health-related quality of life (HRQoL) of patients and their families.
A. Bosch   +7 more
semanticscholar   +1 more source

CHINA’S LAND FINANCE AS ACTIVE MODE OF LAND DEVELOPMENT AND INFRASTRUCTURE DELIVERY: Reality, History and Prospects

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley   +1 more source

Silencing of juvenile hormone‐related genes through RNA interference leads to molt failure and high mortality in the spongy moth

open access: yesInsect Science, EarlyView.
The feasibility of using RNA interference to control the globally important quarantine pest, the spongy moth. Targeting genes related to JHs play an important role in the growth and development of insects. First, the open reading frames (ORFs) of Ldjhamt and Ldjheh were identified and characterized, and the target genes were cloned and double‐stranded ...
Wenzhuai Ji   +3 more
wiley   +1 more source

The Shared Genetic Architecture of Modifiable Risk for Dementia and its Influence on Brain Health [PDF]

open access: yes, 2022
Targeting modifiable risk factors for dementia may prevent or delay dementia. However, the mechanisms by which risk factors influence dementia remain unclear and current research often ignores commonality between risk factors.
Foote, I
core  

The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg   +9 more
wiley   +1 more source

Phenylketonuria [PDF]

open access: yesBMJ, 1963
J D, ALLAN   +3 more
openaire   +2 more sources

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