Results 1 to 10 of about 719 (122)
Oxygen rearrangement of molecular ions of 3-phenylpropionates
AbstractThe oxygen rearrangement in molecular ions of 3‐phenylpropionates has been investigated with the aid of mass analyzed ion kinetic energy spectra. Elimination of an allyl radical followed by expulsion of ketene from the molecular ion of allyl 3‐phenylpropionate is shown to result in formation of protonated benzaldehyde.
Joachim G Liehr +2 more
exaly +3 more sources
Lipase-catalyzed hydrolytic resolution of (R,S)-3-hydroxy-3-phenylpropionates in biphasic media
Pei-Yun Wang, Shau-Wei Tsai
exaly +2 more sources
A Chirality Chain in Phenylglycine, Phenylpropionic Acid, and Ibuprofen [PDF]
Our strategy to analyze the structures of natural amino acids with respect to the interaction of three different elements of chirality within the molecules was applied to the non-natural amino acid (S)-α-phenylglycine, its analogue (S)-α-phenylpropionic acid, and the drug (S)-ibuprofen.
Henri Brunner +2 more
openaire +1 more source
Microbial Hydroxylation of 2-Phenylpropionic Acid [PDF]
The hydroxylation of 2-phenylpropionic acid (PPH) to 2-(p-hydroxyphenyl)propionic acid (HPPH) was investigated using various microorganisms. The highest hydroxylating activity was found in Streptomyces rimosus ATCC 10907. The reaction product was isolated and identified as 2-(p-Miydroxyphenyl)propionic acid, which had no specific rotation, indicating ...
KUGE, Yukihiro +2 more
openaire +2 more sources
The metabolism of β-phenylpropionic acid by an Achromobacter [PDF]
1. When a species of Achromobacter grew with beta-phenylpropionate as carbon source, 2-hydroxy-beta-phenylpropionate and 2,3-dihydroxy-beta-phenylpropionate appeared in the growth medium. The concentrations of these compounds were maximal during exponential growth. 2.
S, Dagley, P J, Chapman, D T, Gibson
openaire +2 more sources
Ethyl 3-(diphenylphosphinoyl)-3-phenylpropionate
The title compound, Ph2P(O)CH(Ph)CH2COOEt or C23H23O3P, (I), assembles into columns extending down the a axis, via C—H⋯O hydrogen bonds. Compound (I) was isolated as a by-product in studies related to the development of a novel cyclization reaction [Evans et al. (2002). Tetrahedron Lett.
Light, M. E. +3 more
openaire +3 more sources
Cytotoxic lignans from Cryptocarya impressinervia
Chemical investigation of the twigs of Cryptocarya impressinervia yielded 23 known compounds including 8 lignans, 3 phenylpropionates, 1 xanthone, 3 flavonoids, 1 phenylpropanoid, 1 substitued phenol, 1 triterpenoid, 3 sterols and 2 aliphatic compounds ...
Jinhe Jiang (665606) +2 more
core +1 more source
Syntheses of deuterated phenylpropionic acid derivatives.
2-(4-(2-Thienylhydroxymethyl)phenyl) propionic acid (I), 2-(4-carboxyphenyl) propionic acid (II), 2-(4-(5-hydroxy-2-thienylcarbonyl)phenyl)propionic acid (III) were labeled with multiple-deuterium for the purpose of using as internal standards in studies on the metabolism of 2-(4-(2-thienylcarbonyl)phenyl)propionic acid (suprofen, IV), anti ...
MORI, Yukio +5 more
openaire +3 more sources
A small-molecule degron with a phenylpropionic acid scaffold
Targeted protein degradation (TPD), employing proteolysis-targeting chimeras (PROTACs) composed of ligands for both a target protein and ubiquitin ligase (E3) to redirect the ubiquitin-proteasome system (UPS) to the target protein, has emerged as a promising strategy in drug discovery.
Shusuke Tomoshige +9 more
openaire +2 more sources

