Results 1 to 10 of about 712 (119)

Microbial Hydroxylation of 2-Phenylpropionic Acid [PDF]

open access: yesAgricultural and Biological Chemistry, 1991
The hydroxylation of 2-phenylpropionic acid (PPH) to 2-(p-hydroxyphenyl)propionic acid (HPPH) was investigated using various microorganisms. The highest hydroxylating activity was found in Streptomyces rimosus ATCC 10907. The reaction product was isolated and identified as 2-(p-Miydroxyphenyl)propionic acid, which had no specific rotation, indicating ...
KUGE, Yukihiro   +2 more
openaire   +2 more sources

A Chirality Chain in Phenylglycine, Phenylpropionic Acid, and Ibuprofen [PDF]

open access: yesSymmetry, 2020
Our strategy to analyze the structures of natural amino acids with respect to the interaction of three different elements of chirality within the molecules was applied to the non-natural amino acid (S)-α-phenylglycine, its analogue (S)-α-phenylpropionic acid, and the drug (S)-ibuprofen.
Henri Brunner   +2 more
openaire   +1 more source

The metabolism of β-phenylpropionic acid by an Achromobacter [PDF]

open access: yesBiochemical Journal, 1965
1. When a species of Achromobacter grew with beta-phenylpropionate as carbon source, 2-hydroxy-beta-phenylpropionate and 2,3-dihydroxy-beta-phenylpropionate appeared in the growth medium. The concentrations of these compounds were maximal during exponential growth. 2.
S, Dagley, P J, Chapman, D T, Gibson
openaire   +2 more sources

Ethyl 3-(diphenylphosphinoyl)-3-phenylpropionate

open access: yesActa Crystallographica Section E Structure Reports Online, 2002
The title compound, Ph2P(O)CH(Ph)CH2COOEt or C23H23O3P, (I), assembles into columns extending down the a axis, via C—H⋯O hydrogen bonds. Compound (I) was isolated as a by-product in studies related to the development of a novel cyclization reaction [Evans et al. (2002). Tetrahedron Lett.
Light, M. E.   +3 more
openaire   +3 more sources

A small-molecule degron with a phenylpropionic acid scaffold

open access: yesBioorganic & Medicinal Chemistry
Targeted protein degradation (TPD), employing proteolysis-targeting chimeras (PROTACs) composed of ligands for both a target protein and ubiquitin ligase (E3) to redirect the ubiquitin-proteasome system (UPS) to the target protein, has emerged as a promising strategy in drug discovery.
Shusuke Tomoshige   +9 more
openaire   +2 more sources

Syntheses of deuterated phenylpropionic acid derivatives.

open access: yesRADIOISOTOPES, 1983
2-(4-(2-Thienylhydroxymethyl)phenyl) propionic acid (I), 2-(4-carboxyphenyl) propionic acid (II), 2-(4-(5-hydroxy-2-thienylcarbonyl)phenyl)propionic acid (III) were labeled with multiple-deuterium for the purpose of using as internal standards in studies on the metabolism of 2-(4-(2-thienylcarbonyl)phenyl)propionic acid (suprofen, IV), anti ...
MORI, Yukio   +5 more
openaire   +3 more sources

Ethyl 2-methoxycarbonylamino-3-phenylpropionate

open access: yesActa Crystallographica Section E Structure Reports Online, 2005
The title compound, C13H17NO4, has been obtained as an unexpected product when attempting to prepare diethyl (S)-2-(2-methoxy­carbonyl­amino-3-phenyl­propionyl)­malonate. The crystal structure involves intermolecular N—H⋯O hydrogen bonds.
Tan, B, Fang, H, Wei, ZB, Jin, LR
openaire   +2 more sources

Moderator Effects on Recoil Tritium Reactions with Lithium β-Phenylpropionate

open access: yesRADIOISOTOPES, 1984
The recoil tritium reactions were studied with lithium beta-phenylpropionate having both the aromatic and aliphatic C-H bonds in the molecule, mainly in terms of the moderator effect on the intramolecular tritium distribution. Recoil tritium atoms were produced by the 6Li(n,alpha)3H reaction. Water molecules were used as the moderator.
OOHASHI, Kunio, MORIKAWA, Naotake
openaire   +3 more sources

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