Results 181 to 190 of about 93,963 (358)

PHARMACOLOGICAL EVALUATION OF LEVETIRACETAM AS ADD-ON DRUG TO EITHER PHENYTOIN OR SODIUM VALPROATE IN PATIENTS OF GENERALIZED ONSET TONIC-CLONIC SEIZURES HAVING BREAKTHROUGH SEIZURES: A RANDOMIZED AND COMPARATIVE STUDY

, 2023
Saroj Kothari, VINEET CHATURVEDI, Ajay Gupta, Dinesh Udainiya   +3 more
openalex   +2 more sources

A Rational Approach to Pharmacotherapy in Pregnancy

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen, Kevin Watt, Ahizechukwu C. Eke   +2 more
wiley   +1 more source

Psychosis as harbinger of phenytoin toxicity

, 2015
M Borasi, R Pravin Verma, Sumit Kumar Gupta   +2 more
openalex   +2 more sources

Lipid-Based Delivery System for Topical Phenytoin [PDF]

, 2016
Siang Yin Lee, Yeong Pung, Boon Khor, Wei Kong, Cai Tan, Siew Yong Teo   +5 more
openalex   +1 more source

P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy

British Journal of Pharmacology, Volume 183, Issue 2, Page 296-312, January 2026.
Background and Purpose Neuroinflammation is increasingly recognised to contribute to drug‐resistant epilepsy. Activation of ATP‐gated P2X7 receptors has emerged as an important upstream mechanism, and increased P2X7 receptor expression is present in the seizure focus in rodent models and patients. Pharmacological antagonists of P2X7 receptors attenuate
Jaideep Kesavan, Yitao Wang, Klaus Dinkel, Michael Hamacher, Jochen H. M. Prehn, David C. Henshall, Tobias Engel   +6 more
wiley   +1 more source

Phenytoin Toxicity Presenting as Encephalopathy With Fatal Outcome: A Case Report

, 2013
Sharma
openalex   +1 more source

Ultra‐Processed Foods Reduction Enhances Clinical Outcomes and Dietary Profiles in Patients With Gingivitis: Results From a Randomised Controlled Trial

Journal of Clinical Periodontology, Volume 53, Issue 1, Page 12-25, January 2026.
ABSTRACT Aim To evaluate the impact of ultra‐processed foods reduction advice (UPF‐RA) on gingivitis treatment and dietary patterns. Methods Young adults with gingivitis were randomly assigned to two groups. At baseline, test group participants received UPF‐RA.
Nicola Discepoli, Isabella De Rubertis, Giulia Tavella, Arianna Guazzelli, Styliani Konstantinidou, Barbara Paolini   +5 more
wiley   +1 more source

ABC of monitoring drug therapy. Phenytoin. [PDF]

, 1992
J K Aronson, M. Hardman, David J. Reynolds   +2 more
openalex   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, Volume 12, Issue 47, December 18, 2025.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Comparison of monotherapy effect of phenytoin, carbamazapine and valproic acid in pediatric general tonic clonic and partial epilepsy

, 2008
Muchamad Budi Nugroho, Elisabeth Siti Herini, Sunartini Sunartini   +2 more
openalex   +2 more sources