Results 71 to 80 of about 2,990 (179)

Interleukin-15Rα-Sushi-Fc Fusion Protein Co-Hitchhikes Interleukin-15 and Pheophorbide A for Cancer Photoimmunotherapy

open access: yesPharmaceutics
Background: Interleukin-15 (IL-15) stimulates the proliferation of natural killer cells or T cells, which, in combination with photodynamic therapy (PDT), has emerged as an effective strategy for cancer photoimmunotherapy.
Zhe Li   +9 more
doaj   +1 more source

Inactivation of Mitochondrial Electron Transport by Photosensitization of a Pheophorbide a Derivative

open access: yesMolecules and Cells, 2004
We examined the damage to mitochondrial electron transport caused by photosensitization of a pheophorbide a derivative, DH-I-180-3, shown recently to induce necrosis of lung carcinoma cells with low dark toxicity. Confocal microscopy showed that DH-I-180-3 co-localized with dihydrorhodamine-123 suggesting that it mainly accumulates in mitochondria. The
Chang Su, Kim   +3 more
openaire   +2 more sources

Pheophorbide a effect upon dark- and photooxidation of olefins

open access: yesТонкие химические технологии, 2006
Peculiarities of pheophorbide’s a behavior in conditions of photosensitized and dark oxidation of natural olefin limonene have been analyzed. It is shown that phaeophorbide a is the photosensitizer of limonene oxidation, but it does not act upon its dark
O. V. Kradenova   +4 more
doaj  

Abstracts

open access: yesMolecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Photochemical Redox Reactions of Catecholamines: Detection of Cyclized Oxidation Products and Boronate Esters

open access: yesPhotochem
Our recent work has focused on red light-mediated photoreduction of p-benzoquinones and both o-, and p-naphthoquinones using methylene blue and the chlorophyll metabolite, pheophorbide A as photosensitizers.
Lisa M. Landino   +4 more
doaj   +1 more source

Liposomes-based co-delivery of pheophorbide a and gold nanoparticles for thermo-photodynamic therapy purpose on lung cancer spheroids

open access: yesResults in Chemistry
Co-delivery of drugs in nanotechnology is a novel area of cancer therapy. In this study, we designed and synthesized a new nanocomplex (Lipo@AuNPs@PPBa) as photosensitizer (PS) from gold nanoparticles (AuNPs) and pheophorbide a (PPBa) for photodynamic ...
Kave Moloudi   +2 more
doaj   +1 more source

Photochemical Redox Cycling of Naphthoquinones Mediated by Methylene Blue and Pheophorbide A

open access: yesMolecules
The photoreduction of plastoquinone, a para-benzoquinone, by chlorophyll initiates photosynthesis in chloroplasts. The direct photoreduction of biologically relevant quinones by dietary chlorophyll metabolites has been reported and may influence health ...
Lisa M. Landino, Joseph A. Reed
doaj   +1 more source

Identification of 69 magnesium-free chlorophyll derivatives in decarboxylated extracts of medical Cannabis chemovars using ESI-LC-HRMS/MS

open access: yesTalanta Open
The Cannabis plant contains many groups of bioactive metabolites with potential pharmacological properties. These properties have mainly been attributed to cannabinoids and terpenoids, with other groups receiving little attention.
Anna Shapira   +5 more
doaj   +1 more source

Mechanistic insights into apoptosis induced by green synthesized liposomal gold nanoparticles enhancing photodynamic therapy in triple-negative breast cancer

open access: yesResults in Chemistry
Breast cancer still presents a major challenge in oncology, even with treatment advances. Its complexity is attributed to high mortality, late-stage diagnosis, and the development of resistance to conventional therapies such as surgery, chemotherapy ...
Mehak Zahra   +2 more
doaj   +1 more source

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