Results 61 to 70 of about 5,603 (210)

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

open access: yesAdvanced Science, Volume 13, Issue 10, 18 February 2026.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao   +6 more
wiley   +1 more source

Constituents of Aquilaria sinensis Leaves Upregulate the Expression of Matrix Metalloproteases 2 and 9

open access: yesMolecules, 2021
In this novel study, we isolated 28 compounds from the leaves of Aquilaria sinensis (Lour.) Gilg based on a bioassay-guided procedure and also discovered the possible matrix metalloprotease 2 (MMP-2) and 9 (MMP-9) modulatory effect of pheophorbide A (PA).
Sui-Wen Hsiao   +5 more
doaj   +1 more source

Aggregation of metallochlorophylls - Examination by spectroscopy [PDF]

open access: yes, 1969
Nuclear magnetic resonance measurements determine which metallochlorophylls, besides magnesium-containing chlorophylls, possess coordination aggregation properties.
Boucher, L. J., Katz, J. J.
core   +1 more source

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]

open access: yes, 2006
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Adachi Y   +48 more
core   +1 more source

Cyclopeptidic photosensitizer prodrugs as proteolytically triggered drug delivery systems of pheophorbide A: part II–co-loading of pheophorbide A and black hole quencher

open access: yesPhotochemical & Photobiological Sciences, 2018
Previously, we have shown that the use of a cyclopeptidic carrier could be of great interest for the design of fully characterized prodrugs for further use in photodynamic therapy. In order to further optimize the design, we decided to modify the highly quenched conjugate uPA-cPPP4/5 by co-loading a long-distance fluorescence quencher. For this purpose
Bouilloux, Jordan   +7 more
openaire   +3 more sources

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Self-Assembly of Pheophorbide-a on Poly-L-Lysine

open access: yes, 2021
16 pages, 8 ...
Ryazanova, Olga   +3 more
openaire   +2 more sources

Impact of Passive Solar Drying and Storage on Secondary Plant Metabolites and Nitrate Contents of Abyssinian Mustard, Amaranth, and Pumpkin Leaves

open access: yesJournal of Food Science, Volume 91, Issue 1, January 2026.
ABSTRACT The present study compared the effect of passive direct solar dryer (PDSD) and passive indirect solar dryer (PISD), each followed by a 30‐day storage period, on the secondary plant metabolite and nitrate contents of amaranth, Abyssinian mustard, and pumpkin leaves.
James S. Chacha   +4 more
wiley   +1 more source

A naturally occurring epiallele associates with leaf senescence and local climate adaptation in Arabidopsis accessions

open access: yesNature Communications, 2018
Epigenetic variation underlies various aspects of phenotypic diversity of plants. Here, He et al show a naturally occurring epiallele controls Arabidopsis leaf senescence by regulating the expression of PHEOPHYTIN PHEOPHORBIDE HYDROLASE (PPH), and is ...
Li He   +10 more
doaj   +1 more source

Breast cancer as photodynamic therapy target: Enhanced therapeutic efficiency by overview of tumor complexity [PDF]

open access: yes, 2014
Photodynamic therapy is a minimally invasive and clinically approved procedure for eliminating selected malignant cells with specific light activation of a photosensitizer agent.
Lamberti, María Julia   +2 more
core   +1 more source

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