Results 41 to 50 of about 2,990 (179)

Photodynamic Therapy Using Pheophorbide a and Nd:YAG Laser

Neurologia medico-chirurgica, 1991
The authors describe a new photodynamic therapy (PDT) method for malignant brain tumors. Pheophorbide a (Ph-a), the photosensitizer, has low toxicity, causes no skin sensitization and is activated with an acoustic Q switched neodymium yttrium-argon-garnet (Nd:YAG) laser which achieves deep tissue penetration.
FUJISHIMA, Ichiro, SAKAI, Tsuneo, TANAKA, Tokutaro, RYU, Hiroshi, UEMURA, Kenichi, FUJISHIMA, Yuriko, HORIUCHI, Kentaro, DAIKUZONO, Norio, SEKIGUCHI, Yoshio   +8 more
openaire   +3 more sources

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Propagation of cell death in dropdead1, a sorghum ortholog of the maize lls1 mutant. [PDF]

PLoS ONE, 2018
We describe dropdead1-1 (ded1), an EMS-induced recessive lesion mimic mutant of sorghum. It is characterized by the formation of spreading necrotic lesions that share many attributes with those associated with the maize lethal leaf spot1 (lls1) and ...
Anoop Sindhu, Diane Janick-Buckner, Brent Buckner, John Gray, Usha Zehr, Brian P Dilkes, Gurmukh S Johal   +6 more
doaj   +1 more source

Assessment of Phytochemical Compounds and Antioxidant Potential of West Indian Avocado (Persea americana) Peel From Substandard‐Quality Fruits as a Valorisation Strategy

Phytochemicals in Food and Medicine, Volume 1, Issue 4, December 2026.
West Indian avocado peels discarded because of low‐commercial‐quality were evaluated as a source of bioactive compounds. Avocado peels contained high levels of phenolic compounds and showed strong antioxidant capacity. These results support avocado peel valorisation within functional foods, circular and sustainable food systems.
Eduardo Castañeda‐Pérez, Josabet Uuh‐Narváez, Luis Chel‐Guerrero, Arturo Castellanos‐Ruelas, David Betancur Ancona   +4 more
wiley   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, Volume 41, Issue 10, Page 807-821, October 2026.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

A naturally occurring epiallele associates with leaf senescence and local climate adaptation in Arabidopsis accessions

Nature Communications, 2018
Epigenetic variation underlies various aspects of phenotypic diversity of plants. Here, He et al show a naturally occurring epiallele controls Arabidopsis leaf senescence by regulating the expression of PHEOPHYTIN PHEOPHORBIDE HYDROLASE (PPH), and is ...
Li He, Wenwu Wu, Gaurav Zinta, Lan Yang, Dong Wang, Renyi Liu, Huiming Zhang, Zhimin Zheng, Huan Huang, Qingzhu Zhang, Jian-Kang Zhu   +10 more
doaj   +1 more source

Genome‐Wide Screening and Functional Verification of the Tobacco SGR Family Identify Transcription‐Factor‐Like NtSGRL as a Negative Regulator of Tomato Yellow Leaf Curl Virus Resistance

Molecular Plant Pathology, Volume 27, Issue 10, October 2026.
A chloroplast‐associated STAY‐GREEN protein, NtSGRL1, acts as a negative regulator of antiviral immunity in tobacco. Disruption of NtSGRL1 enhances resistance to diverse plant viruses and reveals a previously unrecognized link between chloroplast regulation and immune signalling.
Ming Gu, Kexin Cao, Jiamin Yu, Dongyang Liu, Bin Zhao, Siyu Sun, Zhenhong Zhu, Mengnan An, Zihao Xia, Zhiping Wang, Yuanhua Wu   +10 more
wiley   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, Volume 3, Issue 3, Page 125-135, September 2026.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

Viruses in the sediments around the trenches harbor diverse survival mechanisms

iMetaOmics, Volume 3, Issue 3, September 2026.
Deep‐sea trenches are the deepest and most isolated environments in the global ocean but the diversity and adaptation of the viral communities remain poorly characterized. In this study, 5563 viral operational taxonomic units (vOTUs) were identified from sediments of the Yap Trench and Western Caroline Basin.
Yue Su, Hao Yu, Shujuan Sun, Kaiyang Zheng, Ziyue Wang, Chen Gao, Guangxue Li, Xiaoshou Liu, Hongbing Shao, David Paez‐Espino, Andrew McMinn, Yantao Liang, Min Wang   +12 more
wiley   +1 more source

Histological Changes of Hypersensitized Rats by Pheophorbide

Eiyo To Shokuryo, 1977
野沢菜漬物中に含まれるヘオホーバイドによるラットの光過敏症の成立とそのメカニズム解明のため, 今回はヘオホーバイドのケイ光性を利用し, ラットの体内分布を観察した。その結果, 網内系細胞の多い大網膜, 脾臓への取り込みが顕著であった。また, 多少, 心臓, 肝臓への取り込みも見られたが, それほど大きなものではなかった。さらに, 光過敏症によってラットの臓器 (脳, 胸腺, 肺臓, 心臓, 肝臓, 副腎, 腎臓, 脾臓, 胃, 腸, 子宮, 膀胱, 筋肉, 背の皮膚) が組織学的にどのような変化を受けているのかを観察するため光学顕微鏡をつかって検討した結果, 脾臓において, とくに著しい変化が認められた。リンパ濾胞のくずれ, 細胞の崩壊が顕著であること, また, この崩壊細胞は濾胞内 (白髄 ...
ISOBE, Akihiko, SASAKI, Rikuro, KIMURA, Shuichi   +2 more
openaire   +2 more sources