Results 21 to 30 of about 2,897 (173)

Pheophorbide a Is a Specific Probe for ABCG2 Function and Inhibition [PDF]

Cancer Research, 2004
Abstract Pheophorbide a (PhA), a chlorophyll catabolite, was shown to be an ABCG2 substrate based on Abcg2−/− knockout mouse studies (J. W. Jonker et al., Proc. Natl. Acad. Sci. USA, 99: 15649–15654, 2002). We developed a functional assay for ABCG2 using PhA and the ABCG2 inhibitor fumitremorgin C.
Robert W, Robey, Kenneth, Steadman, Orsolya, Polgar, Kuniaki, Morisaki, Margaret, Blayney, Prakash, Mistry, Susan E, Bates   +6 more
openaire   +2 more sources

Pheophorbide a as a photosensitizer in photodynamic therapy: In vivo considerations [PDF]

Cancer Biology & Therapy, 2009
Commentary to:Pheophorbide a based photodynamic therapy induces apoptosis via mitochondrial-mediated pathway in human uterine carcinosarcoma Patrick Ming-Kuen Tang, Xiao-Zhuo Liu, Dong-Mei Zhang, Wing-Ping Fong and Kwok-Pui ...
Theresa, Busch, Keith A, Cengel, Jarod, Finlay   +2 more
openaire   +2 more sources

Pheophorbide Derivatives Isolated From Açaí Berries () Activate an Antioxidant Response Element In Vitro

Natural Product Communications, 2019
Activity-guided fractionation was used to isolate and identify 2 components of the Brazilian açaí berry ( Euterpe oleracea Mart.) with the ability to induce antioxidant response element (ARE)-dependent gene transcription in human hepatoma (HepG2) cells ...
Suneel K. Kandagatla, Robin Tate Uhl, Tyler N. Graf, Nicholas H. Oberlies, Gregory M. Raner   +4 more
doaj   +1 more source

Concurrent Photooxidation and Photoreduction of Catechols and Para-Quinones by Chlorophyll Metabolites

Photochem
Photosynthesis is initiated when the sun’s light induces electron transfer from chlorophyll to plastoquinone, a para-quinone. While photosynthesis occurs in the intact chloroplasts of living plants, similar photochemical reactions between dietary ...
Katherine Phan, Emily E. Lessard, Joseph A. Reed, Meredith G. Warsen, Soren Zimmer, Lisa M. Landino   +5 more
doaj   +1 more source

Photomediated Larvicidal Activity of Pheophorbide a against Cercaria Larvae of Fasciola gigantica

Scientifica, 2017
Fasciolosis is a parasitic disease caused by Fasciola gigantica. The freshwater snail Lymnaea acuminata is the intermediate host of F. gigantica which cause endemic fasciolosis in the northern part of India. To investigate larvicidal activity of pure and
Divya Jyoti Singh, Vinay Kumar Singh, D. K. Singh   +2 more
doaj   +1 more source

OPTIMIZATION OF CONDITION FOR METHYL PHEOPHORBIDE A FORMATION AND CONVERSION TO CHLORIN E6

Tạp chí Khoa học
Chlorin e6 is a stable chlorophyll derivative and can be used in photodynamic therapy (PDT) to treat cancer. One of the synthetic pathways of chlorin e6 is via the transformation of chlorophyll a to methyl pheophorbide a.
Nguyen Thi Thao, Vu Hong Son, Bui Kim Hoan, Nguyen Thi Minh Tu, Nguyen Thi Lan Anh, Nguyen Thanh Phuong*, Le Thi Thao   +1 more
doaj   +1 more source

Drug Release by Direct Jump from Poly(ethylene-glycol-b-ε-caprolactone) Nano-Vector to Cell Membrane

Molecules, 2016
Drug delivery by nanovectors involves numerous processes, one of the most important being its release from the carrier. This point still remains unclear.
Ugo Till, Laure Gibot, Anne-Françoise Mingotaud, Jérôme Ehrhart, Luc Wasungu, Christophe Mingotaud, Jean-Pierre Souchard, Alix Poinso, Marie-Pierre Rols, Frédéric Violleau, Patricia Vicendo   +10 more
doaj   +1 more source

Phototherapeutic effect of transformable peptides containing pheophorbide a on colorectal cancer

Drug Delivery, 2022
Photodynamic therapy (PDT) and photothermal therapy (PTT) have attracted research interest for their noninvasive nature and selective treatment of tumor tissues.
Zhiqin Zhang, Kaixin Wang, Manting Liu, Panxiang Hu, Yuchen Xu, Dongge Yin, Yuchang Yang, Xiaoxv Dong, Changhai Qu, Lu Zhang, Jian Ni, Xingbin Yin   +11 more
doaj   +1 more source

Chemical Constituents From the Aerial Part of (Colebr.) Diels and Their α-Glucosidase and α-Amylase Inhibitory Activity

Natural Product Communications, 2020
Two new fatty acid derivatives identified as 5,7-dihydroxy-6-oxoheptadecanoic acid ( 1 ) and ethyl-5,7-dihydroxy-6-oxooctadecanoate ( 2 ) together with four known compounds, ethyl linolenate ( 3 ), ethyl linoleate ( 4 ), ethyl pheophorbide A ( 5 ), and ...
Emmanuel Ayobami Makinde , Chitchamai Ovatlarnporn, Chonlatid Sontimuang , Gaëtan Herbette, Opeyemi Joshua Olatunji   +4 more
doaj   +1 more source

Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity

Marine Drugs, 2020
Microalgae have been shown to be excellent producers of lipids, pigments, carbohydrates, and a plethora of secondary metabolites with possible applications in the pharmacological, nutraceutical, and cosmeceutical sectors. Recently, various microalgal raw
Chiara Lauritano, Kirsti Helland, Gennaro Riccio, Jeanette H. Andersen, Adrianna Ianora, Espen H. Hansen   +5 more
doaj   +1 more source