Results 21 to 30 of about 2,990 (179)

Exploring the potential of pheophorbide A, a chlorophyll-derived compound in modulating GLUT for maintaining glucose homeostasis

Frontiers in Endocrinology
IntroductionPheophorbide A, a chlorophyll-breakdown product, is primarily investigated for its anti-oxidant and anti-inflammatory activity. Recent reports on pheophorbide A have shown its potential in lowering blood glucose levels, thus leading to the ...
Saptadipa Paul, Anuma Pallavi, Nikhil R. Gandasi, Nikhil R. Gandasi   +3 more
doaj   +1 more source

Concurrent Photooxidation and Photoreduction of Catechols and Para-Quinones by Chlorophyll Metabolites

Photochem
Photosynthesis is initiated when the sun’s light induces electron transfer from chlorophyll to plastoquinone, a para-quinone. While photosynthesis occurs in the intact chloroplasts of living plants, similar photochemical reactions between dietary ...
Katherine Phan, Emily E. Lessard, Joseph A. Reed, Meredith G. Warsen, Soren Zimmer, Lisa M. Landino   +5 more
doaj   +1 more source

Photomediated Larvicidal Activity of Pheophorbide a against Cercaria Larvae of Fasciola gigantica

Scientifica, 2017
Fasciolosis is a parasitic disease caused by Fasciola gigantica. The freshwater snail Lymnaea acuminata is the intermediate host of F. gigantica which cause endemic fasciolosis in the northern part of India. To investigate larvicidal activity of pure and
Divya Jyoti Singh, Vinay Kumar Singh, D. K. Singh   +2 more
doaj   +1 more source

OPTIMIZATION OF CONDITION FOR METHYL PHEOPHORBIDE A FORMATION AND CONVERSION TO CHLORIN E6

Tạp chí Khoa học
Chlorin e6 is a stable chlorophyll derivative and can be used in photodynamic therapy (PDT) to treat cancer. One of the synthetic pathways of chlorin e6 is via the transformation of chlorophyll a to methyl pheophorbide a.
Nguyen Thi Thao, Vu Hong Son, Bui Kim Hoan, Nguyen Thi Minh Tu, Nguyen Thi Lan Anh, Nguyen Thanh Phuong*, Le Thi Thao   +1 more
doaj   +1 more source

Drug Release by Direct Jump from Poly(ethylene-glycol-b-ε-caprolactone) Nano-Vector to Cell Membrane

Molecules, 2016
Drug delivery by nanovectors involves numerous processes, one of the most important being its release from the carrier. This point still remains unclear.
Ugo Till, Laure Gibot, Anne-Françoise Mingotaud, Jérôme Ehrhart, Luc Wasungu, Christophe Mingotaud, Jean-Pierre Souchard, Alix Poinso, Marie-Pierre Rols, Frédéric Violleau, Patricia Vicendo   +10 more
doaj   +1 more source

Phototherapeutic effect of transformable peptides containing pheophorbide a on colorectal cancer

Drug Delivery, 2022
Photodynamic therapy (PDT) and photothermal therapy (PTT) have attracted research interest for their noninvasive nature and selective treatment of tumor tissues.
Zhiqin Zhang, Kaixin Wang, Manting Liu, Panxiang Hu, Yuchen Xu, Dongge Yin, Yuchang Yang, Xiaoxv Dong, Changhai Qu, Lu Zhang, Jian Ni, Xingbin Yin   +11 more
doaj   +1 more source

Chemical Constituents From the Aerial Part of (Colebr.) Diels and Their α-Glucosidase and α-Amylase Inhibitory Activity

Natural Product Communications, 2020
Two new fatty acid derivatives identified as 5,7-dihydroxy-6-oxoheptadecanoic acid ( 1 ) and ethyl-5,7-dihydroxy-6-oxooctadecanoate ( 2 ) together with four known compounds, ethyl linolenate ( 3 ), ethyl linoleate ( 4 ), ethyl pheophorbide A ( 5 ), and ...
Emmanuel Ayobami Makinde , Chitchamai Ovatlarnporn, Chonlatid Sontimuang , Gaëtan Herbette, Opeyemi Joshua Olatunji   +4 more
doaj   +1 more source

Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity

Marine Drugs, 2020
Microalgae have been shown to be excellent producers of lipids, pigments, carbohydrates, and a plethora of secondary metabolites with possible applications in the pharmacological, nutraceutical, and cosmeceutical sectors. Recently, various microalgal raw
Chiara Lauritano, Kirsti Helland, Gennaro Riccio, Jeanette H. Andersen, Adrianna Ianora, Espen H. Hansen   +5 more
doaj   +1 more source

Oxygen-supplying ROS-responsive prodrug for synergistic chemotherapy and photodynamic therapy of colon cancer

Frontiers in Pharmacology
Introduction: The synergistic treatment of chemotherapy and photodynamic therapy (PDT) has remarkable potential in cancer therapy. However, challenges remain, such as unstable chemotherapeutic drug release, suboptimal targeting, and reduced efficacy of ...
Ying Hao, Ying Hao, Tailuo Liu, Tailuo Liu, Hao Zhou, Runhao Xu, Ka Li, Mao Chen, Mao Chen, Yuwen Chen   +9 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source