Results 21 to 30 of about 3,607 (204)

Aggregation-induced stabilization of pheophorbide, a water-soluble chlorophyll derivative [PDF]

Frontiers in Nutrition
BackgroundChlorophyll (Chl) is a valuable natural pigment, but its application is limited by poor water solubility and photoinstability. This study focuses on the preparation of pheophorbide (Phide), a water-soluble chlorophyll derivative, and ...
Yixiao Liu, Yixiao Liu, Yishuang Liu, Yishuang Liu, Yangbin Wang, Yangbin Wang, Shuyu Wang, Shuyu Wang, Shuyi Shi, Shuyi Shi, Fangwei Li, Fangwei Li, Mingyong Zeng, Mingyong Zeng   +13 more
doaj   +2 more sources

Phytochemical Screening of 45-Million-Year-Old Colored Angiosperm Leaves Reveals Distinctive Chlorophyll-Derived and Polyphenolic Pigments. [PDF]

Geobiology
ABSTRACT Present‐day angiosperm plants produce a plethora of metabolites including pigments that serve for important functions such as photosynthesis, protection against light, attraction of pollinators, and defense against microbes and herbivores. However, little is known about phytochemical constituents of ancient angiosperms, their distribution in ...
Wolkenstein K, Müller CE, Engeser M, Frauendorf H, McCoy VE, Gee CT.   +5 more
europepmc   +2 more sources

Improving photodynamic therapy efficacy in bladder cancer using polymer micelle-encapsulated pheophorbide a [PDF]

Translational Oncology
Background: Photodynamic diagnosis (PDD) is widely used in bladder cancer management, enabling fluorescence-guided detection of lesions through intravesical administration of photosensitizers such as hexaminolevulinate (Cysview®/Hexvix®).
Maxime Labroy, Stéphane Chabaud, Maud Durand, Isabelle Fourquaux, Stéphane Bolduc, François Bordeleau, Laure Gibot   +6 more
doaj   +2 more sources

Interaction between pheophorbide a and primary aliphatic amines.

Тонкие химические технологии, 2008
The effect of primary aliphatic amine structure and conditions (solvent, the presence of tertiary amine) in course of its reaction with pheophorbide a and methylpheophorbide a on the yield of the final product – chlorine е6-13-alkylamide has been shown.
Е. А. Larkina, A. L.A. Bui, E. P. Tkachevskaya, A. F. Mironov   +3 more
doaj   +1 more source

Phenotypic screening in zebrafish larvae identifies promising cyanobacterial strains and pheophorbide a as insulin mimetics [PDF]

Scientific Reports
Diabetes is a pandemic disease that causes the loss of control of glucose regulation in the organism, in consequence of dysfunction of insulin production or functionality.
Tiago Ribeiro, Mariana Reis, Vitor Vasconcelos, Ralph Urbatzka   +3 more
doaj   +2 more sources

Self-Assembled Nanoparticles with Kynureninase-Fc Fusion Protein and Pheophorbide A for Photodynamic Immunometabolic Cancer Therapy [PDF]

Journal of Functional Biomaterials
Background/Objectives: Aberrant metabolism in tumors exacerbates the immunosuppressive tumor microenvironment. The immunosuppressive metabolite kynurenine inhibits the activation of effector T cells.
Chen Zhang, Afeng Yang, Hongzheng Lin, Zhe Li, Wei Lu   +4 more
doaj   +2 more sources

Nanoparticles improved pheophorbide-a mediated photodynamic therapy for cancer. [PDF]

Lasers Med Sci
Abstract The increased cancer incidence and mortality rates have made researchers continue to explore different types of effective and less toxic cancer therapies. Photodynamic therapy (PDT) is an alternative cancer treatment modality with reduced side effects.
Fakudze N, Abrahamse H, George B.
europepmc   +3 more sources

ROS-responsive tegafur-pheophorbide a conjugate-loaded microneedles for deep drug delivery and chemo-photodynamic therapy of superficial tumors [PDF]

International Journal of Pharmaceutics: X
Superficial tumors, including breast cancer, melanoma, and oral carcinoma, pose significant treatment challenges due to their anatomical location and the inherent limitations of conventional therapies, such as systemic toxicity and poor tumor specificity.
Anning Li, Yingjie Ma, Yunfeng Dai, Yibin Guo, Yanjun He, Sihan Chen, Xinjie Su, Chenxi Fang, Long Chen, Meitao Duan, Ming Chen, Jungang Ren, Li Wang, Chen Wang, Zhiqiang Zhang   +14 more
doaj   +2 more sources

The metabolic ability of swallowtails results in the production of bioactive substances from plant components. [PDF]

PLoS ONE
Host plant selection may depend on the metabolic system in herbivorous insects. Although oligophagous insects take up specific host plant components, how host plant components and their biological activities are altered through their metabolic systems ...
Miho Nakano, Takuma Sakamoto, Yoshiyuki Itoh, Yoshikazu Kitano, Kaori Tsukakoshi, Hidemasa Bono, Hiroko Tabunoki   +6 more
doaj   +2 more sources

Pheophorbide a effect upon dark- and photooxidation of olefins

Тонкие химические технологии, 2006
Peculiarities of pheophorbide’s a behavior in conditions of photosensitized and dark oxidation of natural olefin limonene have been analyzed. It is shown that phaeophorbide a is the photosensitizer of limonene oxidation, but it does not act upon its dark
O. V. Kradenova, D. A. Krugovov, E. A. Larkina, E. P. Tkachevskaya, O. T. Kasaikina   +4 more
doaj   +1 more source