Results 11 to 20 of about 5,603 (210)

Pheophorbide a-mediated sonodynamic, photodynamic and sonophotodynamic therapies against prostate cancer

Photodiagnosis and Photodynamic Therapy, 2020
Anticancer efficiencies and mechanisms of Pheophorbide-a-mediated photodynamic, sonodynamic and sonophotodynamic therapies were investigated in vitro using androgen-sensitive (LNCaP) and androgen insensitive (PC3) prostate cancer cell lines. The cells were incubated in RPMI-1640 media at various concentrations of Pheophorbide-a.
Mehran Aksel, Ozlem Bozkurt-Girit, Mehmet Dincer Bilgin   +2 more
openaire   +4 more sources

Interleukin-15Rα-Sushi-Fc Fusion Protein Co-Hitchhikes Interleukin-15 and Pheophorbide A for Cancer Photoimmunotherapy [PDF]

Pharmaceutics
Background: Interleukin-15 (IL-15) stimulates the proliferation of natural killer cells or T cells, which, in combination with photodynamic therapy (PDT), has emerged as an effective strategy for cancer photoimmunotherapy.
Zhe Li, Jiaojiao Xu, Hongzheng Lin, Sheng Yu, Jingwen Sun, Chen Zhang, Sihang Zhang, Tingting Li, Afeng Yang, Wei Lu   +9 more
doaj   +2 more sources

Interaction between pheophorbide a and primary aliphatic amines.

Тонкие химические технологии, 2008
The effect of primary aliphatic amine structure and conditions (solvent, the presence of tertiary amine) in course of its reaction with pheophorbide a and methylpheophorbide a on the yield of the final product – chlorine е6-13-alkylamide has been shown.
Е. А. Larkina, A. L.A. Bui, E. P. Tkachevskaya, A. F. Mironov   +3 more
doaj   +1 more source

Photochemical Redox Cycling of Naphthoquinones Mediated by Methylene Blue and Pheophorbide A [PDF]

Molecules
The photoreduction of plastoquinone, a para-benzoquinone, by chlorophyll initiates photosynthesis in chloroplasts. The direct photoreduction of biologically relevant quinones by dietary chlorophyll metabolites has been reported and may influence health ...
Lisa M. Landino, Joseph A. Reed
doaj   +2 more sources

Photosensitizing Lipid Nanoparticles for Ferroptosis-Enhanced Photodynamic Cancer Therapy via GPX4 Silencing. [PDF]

Adv Healthc Mater
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Bae GH, Shin S, Park JD, Koh EY, Ko S, Han J, Park CG, Kim DH, Na K, Park W.   +9 more
europepmc   +2 more sources

Effect of Slightly Acidic Electrolyzed Water on Chlorophyll Degradation in Postharvest Broccoli [PDF]

Shipin Kexue, 2023
To explore the effect of slightly acidic electrolyzed water (SAEW) on chlorophyll degradation in postharvest broccoli, the pattern of changes in the color, total chlorophyll content, chlorophyll derivative content, chlorophyll degrading enzyme activities,
HAN Ying, SUN Ying, GUO Feng, WANG Xinyu, ZHAO Anqi, WU Zhaoxia, LI Pengxia, LI Guofeng, HU Huali
doaj   +1 more source

Phytochemical Screening of 45-Million-Year-Old Colored Angiosperm Leaves Reveals Distinctive Chlorophyll-Derived and Polyphenolic Pigments. [PDF]

Geobiology
ABSTRACT Present‐day angiosperm plants produce a plethora of metabolites including pigments that serve for important functions such as photosynthesis, protection against light, attraction of pollinators, and defense against microbes and herbivores. However, little is known about phytochemical constituents of ancient angiosperms, their distribution in ...
Wolkenstein K, Müller CE, Engeser M, Frauendorf H, McCoy VE, Gee CT.   +5 more
europepmc   +2 more sources

Pheophorbide a effect upon dark- and photooxidation of olefins

Тонкие химические технологии, 2006
Peculiarities of pheophorbide’s a behavior in conditions of photosensitized and dark oxidation of natural olefin limonene have been analyzed. It is shown that phaeophorbide a is the photosensitizer of limonene oxidation, but it does not act upon its dark
O. V. Kradenova, D. A. Krugovov, E. A. Larkina, E. P. Tkachevskaya, O. T. Kasaikina   +4 more
doaj   +1 more source

Phototoxicity of Pheophorbide A Extracted from Gracilaria Lemaneiformis on Six Kinds of Cancer Cells

Zhongliu Fangzhi Yanjiu, 2022
Objective To investigate the photodynamic antitumor activity and chemical characteristics of pheophorbide A (PPBa)in vitro. Methods Breast cancer cells (MCF-7), lung cancer cells (A549), cervical cancer cells (HeLa), and three kinds of hepatoma cells ...
HUANG Xixiang, CAI Xiaoxuan, WANG Tianji, HUANG Miaoen, LI Li, LYU Yingnian   +5 more
doaj   +1 more source

Pheophorbide A and Paclitaxel Bioresponsive Nanoparticles as Double-Punch Platform for Cancer Therapy

Pharmaceutics, 2021
Cancer therapy is still a challenging issue. To address this, the combination of anticancer drugs with other therapeutic modalities, such as light-triggered therapies, has emerged as a promising approach, primarily when both active ingredients are ...
Francesca Moret, Luca Menilli, Manuele Battan, Daniele Tedesco, Marta Columbaro, Andrea Guerrini, Greta Avancini, Claudia Ferroni, Greta Varchi   +8 more
doaj   +1 more source