Results 1 to 10 of about 14,174 (198)

Progranulin-driven lysosomal acidification facilitates exocytosis of PHEV-hijacked lysosomes for viral release [PDF]

mBio
Porcine hemagglutinating encephalomyelitis virus (PHEV) hijacks lysosomes, repurposing them as vehicles for viral release by disrupting their function. Progranulin (PGRN), a lysosomal glycoprotein essential for lysosomal regulation, plays a pivotal role ...
Zhenzhen Wang, Yuzhu Chen, Wenqi He, Yuzhu Liu, Yubo Jiao, Gaili Wang, Jiyu Guan, Kui Zhao, Qiaoling Zhang, Feng Gao, Zi Li, Yungang Lan   +11 more
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Porcine hemagglutinating encephalomyelitis virus VW572 (not Gent/PS412 and Labadie) uses the CD81 receptor and MVB-derived exosomal pathway for efficient entry and spread in neuronal cells [PDF]

Journal of Virology
Porcine hemagglutinating encephalomyelitis virus (PHEV) is considered a neurotropic coronavirus that invades the peripheral (PNS) and central (CNS) nervous system of the pig and causes acute encephalomyelitis, also known as “vomiting and wasting disease.”
W. Zaib, C. Kaviani, X. Kang, Y. Gao, F. Vanden Broucke, W. Van den Broeck, S. Coppens, S. Theuns, H. Nauwynck, K. Laval   +9 more
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Seroprevalence of coronaviruses of cattle and pigs in Belgian herds [PDF]

BMC Veterinary Research
Background Bovine coronavirus (BCoV), porcine haemagglutinating encephalomyelitis virus (PHEV), and porcine respiratory coronavirus (PRCV) are common coronaviruses of cattle and swine, but they are rarely monitored.
Ruth M. Mumo, Stefaan Ribbens, Fabien Grégoire, Sebastiaan Theuns, Bart Pardon, Kristien Van Reeth   +5 more
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Development of a quadruplex real-time quantitative RT-PCR for detection and differentiation of PHEV, PRV, CSFV, and JEV [PDF]

Frontiers in Veterinary Science, 2023
Porcine hemagglutinating encephalomyelitis virus (PHEV), porcine pseudorabies virus (PRV), classical swine fever virus (CSFV), and Japanese encephalitis virus (JEV) cause similar neurological symptoms in the infected pigs, and their differential ...
Xin Hu, Shuping Feng, Kaichuang Shi, Kaichuang Shi, Yuwen Shi, Yanwen Yin, Feng Long, Xiankai Wei, Zongqiang Li   +8 more
doaj   +2 more sources

Evolution of the pheV-tRNA integrated genomic island in Escherichia coli. [PDF]

PLoS Genetics
Escherichia coli exhibit extensive genetic diversity at the genome level, particularly within their accessory genome. The tRNA integrated genomic islands (GIs), a part of the E. coli accessory genome, play an important role in pathogenicity.
Nguyen Thi Khanh Nhu, Brian M Forde, Nouri L Ben Zakour, Minh-Duy Phan, Leah W Roberts, Scott A Beatson, Mark A Schembri   +6 more
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Genetic diversity and evolution of porcine hemagglutinating encephalomyelitis virus in Guangxi province of China during 2021–2024 [PDF]

Frontiers in Microbiology
Porcine hemagglutinating encephalomyelitis virus (PHEV) is the only known porcine neurotropic coronavirus, which is prevalent worldwide at present. It is of great significance to understand the genetic and evolutionary characteristics of PHEV in order to
Kaichuang Shi, Kaichuang Shi, Kaichuang Shi, Xin Hu, Feng Long, Yuwen Shi, Yi Pan, Shuping Feng, Zongqiang Li, Yanwen Yin   +9 more
doaj   +2 more sources

DNA vaccine targeting betacoronavirus spike protein blocks neuroinvasion and neuroinflammation in swine via dual antiviral-immunomodulatory action [PDF]

npj Vaccines
Porcine hemagglutinating encephalomyelitis virus (PHEV), a neurotropic betacoronavirus, causes fatal neurological disease in piglets, yet no licensed vaccines exist.
Huabo Yu, Junchao Shi, Guoce Fu, Zezhao Cao, Ruizhao Qiu, Tianqi Zhao, Jing Zhang, Yungang Lan, Jiyu Guan, Kui Zhao, Feng Gao, Wenqi He, Zi Li   +12 more
doaj   +2 more sources

Development of a triplex crystal digital RT-PCR for the detection of PHEV, PRV, and CSFV [PDF]

Frontiers in Veterinary Science
Porcine hemagglutinating encephalomyelitis virus (PHEV), porcine pseudorabies virus (PRV), and classical swine fever virus (CSFV) are currently prevalent worldwide and cause similar neurological symptoms in infected pigs.
Kaichuang Shi, Kaichuang Shi, Kaichuang Shi, Xin Hu, Yanwen Yin, Yuwen Shi, Yi Pan, Feng Long, Shuping Feng, Zongqiang Li   +9 more
doaj   +2 more sources

Transcriptome Analysis in Air–Liquid Interface Porcine Respiratory Epithelial Cell Cultures Reveals That the Betacoronavirus Porcine Encephalomyelitis Hemagglutinating Virus Induces a Robust Interferon Response to Infection [PDF]

Viruses
Porcine hemagglutinating encephalomyelitis virus (PHEV) replicates in the upper respiratory tract and tonsils of pigs. Using an air–liquid interface porcine respiratory epithelial cells (ALI-PRECs) culture system, we demonstrated that PHEV disrupts ...
Kaitlyn M. Sarlo Davila, Rahul K. Nelli, Juan C. Mora-Díaz, Yongming Sang, Laura C. Miller, Luis G. Giménez-Lirola   +5 more
doaj   +2 more sources

Research on PHEV comprehensive fuel consumption based on fuel-electricity conversion [PDF]

E3S Web of Conferences, 2021
In order to show the fuel-saving effect of Plug-in Hybrid Electric Vehicle (PHEV) [1]more intuitively, three conversion methods of fuel and electricity were introduced considering different aspects, namely conversion method of simple calorific value ...
Zhang Luowei, Ma Zhicheng, Niu Zhihai
doaj   +1 more source