Results 121 to 130 of about 80,480 (249)
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) recently celebrated its 20th anniversary, reflecting two decades of major contributions to Alzheimer's research through open data sharing and longitudinal multimodal assessments. This review synthesizes 122 high‐impact studies using ADNI data or biospecimens from 2023 to mid‐2025 to ...
Dallas P. Veitch +22 more
wiley +1 more source
A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia
The Philadelphia (Ph) chromosome breakpoints in chronic myelocytic leukaemia are clustered on chromosome 22 band q11 in a 5.8-kilobase (kb) region designated bcr.
Chan, LC, Karhi, KK, Rayter, SI
core +1 more source
Abstract INTRODUCTION Women are increasingly entering the dementia research workforce, but they frequently fail to attain senior leadership positions in academia. Discrepancies in academic research outputs were investigated to guide equity‐focused policy recommendations.
Jayalakshmi Viswanathan +18 more
wiley +1 more source
Abstract Introduction Elranatamab, approved for relapsed or refractory multiple myeloma, demonstrated deep, durable responses and manageable safety in patients without prior B‐cell maturation antigen (BCMA)‐directed therapy (BCMA‐naive) in MagnetisMM‐3 (NCT04649359). This post hoc analysis evaluated efficacy and safety in the US subgroup.
Ajay K. Nooka +10 more
wiley +1 more source
Genetic testing for familial epilepsies: Diagnostic yield and genetic findings
Abstract Objective Genetic testing has become a routine part of clinical epilepsy care. Family history is an indication for genetic testing, but the diagnostic yield, predictors of a genetic diagnosis, and association with familial patterns are not well understood.
Colin A. Ellis +27 more
wiley +1 more source
Fluorescence in situ hybridization (FISH) has become an increasingly important method for assessing chromosome rearrangement. The reciprocal translocation constituting the Philadelphia (Ph) chromosome [t(9;22)(q34;q11)] characterizes more than 90% of ...
Guan, XY +4 more
core
CEBP and ZEB2 alterations define three distinct subtypes of B‐cell acute lymphoblastic leukemia
Abstract B‐cell acute lymphoblastic leukemia (B‐ALL) is a heterogeneous malignancy driven by diverse genetic alterations. Among these, CEBP family genes and ZEB2 are recurrently involved, yet the spectrum of genomic mechanisms and their clinical impact remain incompletely defined.
Rathana Kim +29 more
wiley +1 more source
HOXA homeogene cluster interruption and dysregulation of HOAX9 in the blast crisis of Philadelphia chromosome-positive chronic myeloid ...
ZUCCHINI, Patrizia +6 more
core
Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya +11 more
wiley +1 more source
Gnavucin D, a novel antibacterial sactipeptide produced by Mediterraneibacter gnavus HB038, exhibits activity against multiple pathogens, including Clostridium perfringens, Streptococcus agalactiae, Bacillus cereus, and vancomycin‐resistant Enterococcus.
Mengfan Ding +9 more
wiley +1 more source

