Results 81 to 90 of about 77,213 (201)

Metabolic dysfunction‐associated steatotic liver disease, insulin resistance and hepatocellular carcinoma: A deadly triad

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a major global cause of liver disease, driven by obesity and insulin resistance (IR). IR promotes hepatic lipid accumulation, inflammation and mitochondrial dysfunction, accelerating MASLD progression to fibrosis, cirrhosis and hepatocellular carcinoma (HCC).
Alfredo Caturano   +15 more
wiley   +1 more source

Efficacy of Momelotinib in Myelofibrosis Patients: Results From a Multicenter Study

open access: yesEuropean Journal of Haematology, Volume 116, Issue 1, Page 23-30, January 2026.
ABSTRACT Momelotinib, a novel JAK1/2 inhibitor with inhibitory activities on activin A receptor type I, has shown breakthrough clinical efficacy in patients with myelofibrosis (MF) and anemia, a disease‐related manifestation of challenging management. In this retrospective real‐life multicenter Italian study, we investigated the safety and efficacy of ...
Maria Carmen Martorelli   +34 more
wiley   +1 more source

PB1891: VARIANT PHILADELPHIA CHROMOSOME IN CML

open access: yesHemaSphere, 2022
N. Bouayed Abdelmoula   +2 more
doaj   +1 more source

The JAK2V617F and CALR mutations and risk of cancer, cardiovascular diseases, and all‐cause mortality

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 79-94, January 2026.
Abstract Background Clonal hematopoiesis (CH) is associated with adverse outcomes. We hypothesized that CH (JAK2V617F and CALR) is associated with cancer, vascular disease, and all‐cause mortality, even at a variant allele frequency (VAF) <1%. Methods We screened 19,832 individuals from the Danish General Suburban Population Study for JAK2V617F and ...
Morten Kranker Larsen   +17 more
wiley   +1 more source

PB1757: VARIANT PHILADELPHIA CHROMOSOME IN ALL

open access: yesHemaSphere, 2022
N. Bouayed Abdelmoula   +4 more
doaj   +1 more source

Novel additional cytogenetic abnormalities associated with Philadelphia chromosome

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
None
Sanjeev Kumar Sharma   +3 more
doaj  

Acquired Philadelphia Chromosome with Transformed Myelodysplastic Syndrome [PDF]

open access: bronze, 2013
Yoshinobu Saito   +5 more
openalex   +1 more source

Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert consensus on the management of renal cell and urinary tract cancers

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
Abstract The therapeutic landscape for renal cell carcinoma (RCC) and urinary tract cancer (UTC) has transformed dramatically, creating complexity in treatment selection and sequencing. The 2025 Advanced Urologic Cancer Consensus Conference was convened to establish evidence‐based expert consensus recommendations for optimal management.
Rana R. McKay   +53 more
wiley   +1 more source

Treating relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia: liposome-encapsulated vincristine

open access: yesInternational Journal of Nanomedicine, 2013
Tyler Davis, Sherif S Farag Department of Internal Medicine, Division of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, IN, USA Abstract: Acute lymphoblastic leukemia (ALL) remains a disease with poor outcomes in adults ...
Davis T, Farag SS
doaj  

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