Results 61 to 70 of about 37,066 (263)

Effect of phlebotomy versus oral contraceptives containing cyproterone acetate on the clinical and biochemical parameters in women with polycystic ovary syndrome: a randomized controlled trial

Journal of Ovarian Research, 2019
Background Reduction of the body iron stores can improve hyperandrogenemia and insulin resistance. This study aimed to compare clinical and para-clinical responses to the treatment of phlebotomy using oral contraceptive pills (OCs) containing cyproterone
Samira Behboudi-Gandevani, Hayedeh Abtahi, Navid Saadat, Maryam Tohidi, Fahimeh Ramezani Tehrani   +4 more
doaj   +1 more source

Emergency department–initiated oral naltrexone for patients with moderate to severe alcohol use disorder: A pilot feasibility study

Academic Emergency Medicine, Volume 32, Issue 5, Page 488-497, May 2025.
Abstract Objectives Alcohol use disorder (AUD) is the most common substance use disorder in the United States. Despite availability of four FDA‐approved medications, fewer than 10% of patients are prescribed medication. This study aimed to evaluate the impact and feasibility of emergency department (ED)‐initiated oral naltrexone in patients with ...
Ethan Cowan, Clare O'Brien‐Lambert, Erick Eiting, Edward Bull, Jacqueline Ryder, Yvette Calderon, Edwin Salsitz   +6 more
wiley   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

Annals of Human Genetics, EarlyView.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk, Nicole Van Der Merwe, Johny Erasmus, Lindiwe Whati, Kelebogile E. Moremi, Daniel W. Olivier, Maritha J. Kotze   +6 more
wiley   +1 more source

Cardiovascular safety of testosterone therapy—Insights from the TRAVERSE trial and beyond: A position statement of the European Expert Panel for Testosterone Research

Andrology, EarlyView.
Abstract Introduction Testosterone therapy has become a cornerstone treatment for men with hypogonadism, offering significant benefits such as improved sexual function, mood, muscle mass, and bone density. However, concerns about its cardiovascular safety have historically tempered its use.
Michael Zitzmann, Giulia Rastrelli, Robert D Murray, David Edwards, Yacov Reisman, Preethi Mohan Rao, Alexander Sahi, Thomas Hugh Jones, Alberto Ferlin, Eleni Armeni, Emiliano Corpas, Jann‐Frederik Cremers, Janine David, Stefan Arver, Leen Antonio, Giovanni Corona   +15 more
wiley   +1 more source

Blood Harmane Concentrations in 497 Individuals Relative to Coffee, Cigarettes, and Food Consumption on the Morning of Testing

Journal of Toxicology, 2011
Harmane, a potent neurotoxin linked with several neurological disorders, is present in many foods, coffee, and cigarettes. We assessed whether morning food/coffee consumption and smoking were reflected in blood harmane concentrations (BHCs) we obtained ...
Elan D. Louis, Pam Factor-Litvak, Marina Gerbin, Wendy Jiang, Wei Zheng   +4 more
doaj   +1 more source

Hereditary hemochromatosis: Retrospective study on clinical data from Emergency County Hospital Mures

Acta Marisiensis - Seria Medica, 2022
Objective: Hereditary hemochromatosis, or primary hemochromatosis, is a recessive genetic liver disorder caused by iron accumulation in tissues. This study evaluates patients with hereditary hemochromatosis to determine correlations between clinical and ...
Sigmirean Victor
doaj   +1 more source

Efficiency evaluation for pooling resources in health care [PDF]

, 2012
Hospitals traditionally segregate resources into centralized functional departments such as diagnostic departments, ambulatory care centers, and nursing wards.
Boucherie, Richard J., Hans, Erwin W., Hurink, Johann L., Litvak, Nelly, Vanberkel, Peter T.   +4 more
core   +2 more sources

Ethical Biobanking in Extremely Preterm Infants: Lessons From the EPITOP Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim The Extremely Preterm Infant Target Optimise and Prevent (EPITOP) study aimed to develop an ethical and practical approach to biobanking salvaged residual blood samples from extremely preterm infants (< 28 weeks gestational age, GA) for biomarker research while minimising clinical risks and addressing ethical concerns. Methods Initiated in
Ulrika Sjöbom, Jenny Isaksson, Ruth Wickelgren, Liv Vallin, Anders K. Nilsson, Ann Hellström, Karin Sävman, Chatarina Löfqvist   +7 more
wiley   +1 more source

Iron overload in hereditary spherocytosis: Are genetic factors the cause?

British Journal of Haematology, EarlyView.
Summary Non‐transfusional iron overload (IOL) in hereditary spherocytosis (HS) is poorly documented compared with other red blood cell disorders. We studied 13 HS adults with confirmed IOL to identify potential genetic factors. Using a next‐generation sequencing panel of 46 genes related to HS, anaemia and iron metabolism, we found no association ...
Lucie Donaty, Muriel Giansily‐Blaizot, Ivan Bertchansky, Séverine Cunat, Vincent Azoury, Perrine Mahe, Patricia Aguilar Martinez   +6 more
wiley   +1 more source

Nurses’ knowledge on phlebotomy in tertiary hospitals in China: a cross-sectional multicentric survey [PDF]

, 2017
Introduction: In China, phlebotomy practice is mostly executed by nurses instead of phlebotomists. Our hypothesis was that these nurses may lack of knowledge on phlebotomy, especially factors influencing quality of blood samples.
Dangan Yang, Qian Cai, Yunxian Zhou
core   +3 more sources