Genetic Characterization of Sandfly-Borne Viruses in Phlebotomine Sandflies in Iran
Phleboviruses are classified into two main groups: the sandfly fever group (transmitted by sandflies and mosquitoes) and the Uukuniemi group (transmitted by ticks).
Nariman Shahhosseini+4 more
doaj +1 more source
Hunter Island Group Phlebovirus in Ticks, Australia
To the Editor: A recent article described the isolation and subsequent analysis of a tickborne phlebovirus: Hunter Island Group virus (HIGV), associated with an albatross disease event that occurred in 2002 on Albatross Island, 6 kilometers off the northwest coast of Tasmania, Australia (1).
Penelope J. Gauci+6 more
doaj +5 more sources
In vitro and in vivo Phlebovirus inhibition by ribavirin [PDF]
Ribavirin (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) was markedly inhibitory in vitro to Adames and Balliet strains of Punta Toro virus (PTV), a Phlebovirus related to Rift Valley fever and sandfly fever viruses. By using inhibition of viral cytopathic effect in LLC-MK2 cells with both virus strains, the 50% effective dose was 4 to 10 ...
Dominique Y. Pifat+3 more
openaire +3 more sources
Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope [PDF]
Significance Bunyaviruses are emerging zoonotic pathogens of public-health concern. Lack of structures for proteins on the viral membrane (“envelope”) surface limits understanding of entry. We describe atomic-level structures for the globular “head” of the envelope protein, glycoprotein N (Gn), from two members, severe fever with
Yan Wu+20 more
openalex +4 more sources
The Unique Phylogenetic Position of a Novel Tick-Borne Phlebovirus Ensures an Ixodid Origin of the Genus Phlebovirus [PDF]
The emergence of novel tick-borne RNA viruses causing severe illness in humans has complicated the epidemiological landscape of tick-borne diseases, requiring further investigation to safeguard public health. In the present study, we discovered a novel tick-borne phlebovirus from Ixodes persulcatus ticks in Japan ...
Keita Matsuno+15 more
openaire +5 more sources
The <i>Bunyavidae</i> family is the largest grouping of RNA viruses and arguably the most diverse. Bunyaviruses have a truly global distribution and can infect vertebrates, invertebrates and plants.
Bird+42 more
core +2 more sources
Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin+2 more
core +1 more source
Background High throughput sequencing (HTS) boosted the discovery of novel viruses and new variants of known viruses. Here we investigated the presence of viruses in 12 pools of sand flies captured in three climatic periods in RAPELD grids at Rio Claro ...
Michellen S. de Carvalho+7 more
doaj +1 more source
Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis [PDF]
Indexación: ScieloWe report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%.
Fernández, Jorge+9 more
core +2 more sources
Characterization of severe fever with thrombocytopenia syndrome in rural regions of Zhejiang, China. [PDF]
Severe fever with thrombocytopenia syndrome virus (SFTSV) infections have recently been found in rural regions of Zhejiang. A severe fever with thrombocytopenia syndrome (SFTS) surveillance and sero-epidemiological investigation was conducted in the ...
feng, Cen+9 more
core +7 more sources