Results 71 to 80 of about 29,210 (237)

Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]

open access: yes, 2009
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K.   +4 more
core   +2 more sources

Identification of Mudanjiang Phlebovirus in the Daxing’anling Region of China

open access: yesViruses, 2023
Mudanjiang phlebovirus (MJPV) is a newly discovered phlebovirus, initially detected from Ixodes persulcatus ticks in China in 2022. In this study, by next-generation sequencing (NGS) on a wide variety of ticks and wild small animals in China, we detected MJPV from I. persulcatus and Meriones meridianus.
Chenli Fang   +15 more
openaire   +3 more sources

A Pyrido‐Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus

open access: yesJournal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti   +11 more
wiley   +1 more source

Lettuce Big‐Vein Associated Virus ORF3 Encodes a Functional 30K Movement Protein

open access: yesMolecular Plant Pathology, Volume 26, Issue 9, September 2025.
AlphaFold2 + FoldSeek structure guided search predicts the movement protein of lettuce big‐vein associated virus despite low sequence similarity. ABSTRACT Movement proteins (MPs) modulate the size exclusion limit of plasmodesmata—membrane‐lined channels connecting plant cells—thereby allowing cell‐to‐cell movement and systemic spread of plant viruses ...
Willem E. W. Schravesande   +4 more
wiley   +1 more source

The Input of Structural Vaccinology in the Search for Vaccines against Bunyaviruses

open access: yesViruses, 2021
A significant increase in the number of viruses causing unexpected illnesses and epidemics among humans, wildlife and livestock has been observed in recent years.
Alexandra Serris
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B.   +4 more
core   +1 more source

Further Characterization of Rio Grande Virus and Potential for Cross Reactivity with Rift Valley Fever Virus Assays

open access: yesViruses, 2021
Phleboviruses (genus Phlebovirus, family Phenuiviridae) are emerging pathogens of humans and animals. Sand-fly-transmitted phleboviruses are found in Europe, Africa, the Middle East, and the Americas, and are responsible for febrile illness and nervous ...
Mitchell S. Szymczak   +2 more
doaj   +1 more source

Medicinal Plant‐Derived Caffeoylquinic Acids as Inhibitors of Rift Valley Fever Virus: A Computational Study

open access: yesChemistrySelect, Volume 10, Issue 12, March 26, 2025.
Caffeoylquinic acids derived from medicinal plants were evaluated for their potential as inhibitors of the Rift Valley Fever Virus, specifically targeting the LRP1‐CR17 protein. The study employed DFT, molecular docking, and molecular dynamics simulations to analyze these compounds. The results showed strong binding affinities to the LRP1‐CR17 receptor,
Garland K. More   +4 more
wiley   +1 more source

Seroprevalence of Toscana Virus and Sandfly Fever Sicilian Virus in European Bat Colonies Measured Using a Neutralization Test

open access: yesViruses, 2021
Toscana phlebovirus (TOSV) and Sicilian phlebovirus (SFSV) are endemic in the Mediterranean area where they are transmitted to humans by infected sandflies.
Nazli Ayhan   +4 more
doaj   +1 more source

First report of the ticks Haemaphysalis punctata Canestrini et Fanzago, 1878, Haemaphysalis parva (Neumann, 1897) and Dermacentor marginatus (Sulzer, 1776) (Acari, Amblyommidae) from humans in Lebanon [PDF]

open access: yes, 2020
Purpose: Knowledge on ticks infesting humans is scarce for the middle East. In this work, tick specimens (Acari: Amblyommidae) infesting humans in Lebanon were identified.
Azar, Dany   +2 more
core   +1 more source

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