In Vitro and In Vivo Comparison of a Novel Antimicrobial Wound Hydrogel With Commercial Wound Treatments: Antimicrobial, Antibiofilm and Biocompatibility Assessment [PDF]
Int Wound JABSTRACT Antimicrobial resistance (AMR) and biofilm formation significantly hinder chronic wound management, necessitating safer and more effective therapeutic options. This study evaluates the antimicrobial, antibiofilm, cytocompatibility and anti‐inflammatory properties of a novel antimicrobial hydrogel Formulation (#1) compared with commercially ...
Moradi M +3 more
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Polyhexanide as a new antiseptic composition for a dentist
Эндодонтия Today, 2021 Aim. To assess systematically the available scientific evidence about clinical response of using polyhexanide as an antiseptic agent in medicine and dentistry.
Z. S. Khabadze +5 more
doaj +1 more source
Veterinary Sciences, 2020 Dogs are the main reservoir for Leishmania infantum, manifesting from a subclinical to a fatal disease. Limited treatments are available, although new antiparasitics and immunomodulators are pursued.
Pamela Martínez-Orellana +3 more
doaj +1 more source
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
, 2016 Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
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Efficacy of surgical antiseptic handrub containing PHMB [PDF]
BMC Proceedings, 2011 The efficacy and cytotoxicity of PHMB (polyhexamethylene biguanide) -containing surgical hand rub was investigated.
Noguchi E, Yamamoto M
openaire +2 more sources
Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics [PDF]
, 2013 A flexible methacrylate powder dressing (Altrazeal®) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics.
Archibald +34 more
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Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]
, 1987 Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger G. +18 more
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Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]
, 2018 The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Chivu, A +3 more
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Pantoea agglomerans in Equine Ulcerative Keratitis: Prevalence and Comparative Efficacy of Four Topical Antiseptics. [PDF]
Vet OphthalmolABSTRACT Objective To determine the minimal bactericidal concentration (MBC) and effective contact time of four topical antiseptics—polyhexanide, povidone‐iodine (PVP‐I), hypochlorous acid (HOCl), and N‐acetylcysteine (NAC)—against Pantoea agglomerans, a pathogen frequently isolated in equine ulcerative keratitis.
Heun F +4 more
europepmc +2 more sources
Testing of a dual-mode microwave care regimen for hydrogel lenses [PDF]
, 2004 Purpose. To test the design of a patient care regimen for soft lenses that aims to provide the highest standards of disinfecting through use of domestic microwave cookers, while also providing storage equipment and solution that enable patients to follow
Crabbe, A, Thompson, P
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