Results 41 to 50 of about 2,769 (189)
Journal of Advanced Research, 2020 Acanthamoeba keratitis (AK) is difficult to treat, especially when the corneal deep stroma is involved. Intrastromal injection of antimicrobial agents is an effective adjuvant therapy for deep recalcitrant microbial keratitis; however, it has not been ...
Chen-Chee Lim +2 more
doaj +1 more source
[Acanthamoeba keratitis treated with propamidine and polyhexamethyl biguanide (PHMB)].
Revista medica de Chile, 2002 The diagnosis of acanthamoeba keratitis has increased since 1985 due to the massive use of contact lenses and a better knowledge of the disease by ophthalmologists. The use of biassociated therapy has resulted in a better prognosis and lower complication rate.To report patients with acanthamoeba keratitis treated with the association of propamidine ...
Rodrigo, Donoso +2 more
openaire +2 more sources
Uptake of PHMB in a bacterial nanocellulose-based wound dressing: A feasible clinical procedure
, 2022 S.898-904Background With the increase of antimicrobial resistance in recent decades, other methods of preventing and fighting infections must be considered.
Funk, Martin +8 more
core +1 more source
, 2015 The bar graphs show the effects of different inhibitors and temperature on cellular uptake of (a) PHMB-FITC, (b) PHMB-FITC/CpG ODN polyplexes, (c) dextran/FITC used as positive control to exclude the effect of FITC that might interfere with the cellular ...
Heidrun Moll (317342) +11 more
core +1 more source
Pathogens, 2023 Papular dermatitis is a cutaneous manifestation of canine Leishmania infantum infection associated with mild disease. Although it is a typical presentation, nowadays, there is still no established treatment.
Icíar Martínez-Flórez +10 more
doaj +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To report medical cure and treatment failure rates of Acanthamoeba keratitis (AK) with respect to type of treatment, disease stage and prognostic factors. Methods Electronic records were reviewed for 45 patients with PCR‐positive AK treated at the Department of Ophthalmology, Aarhus University Hospital, Denmark from 2012 to 2025 ...
Anders Ivarsen +5 more
wiley +1 more source
Determination of polyhexamethylene biguanide hydrochloride
Reviews in Analytical Chemistry, 2014 Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes.
Masadome Takashi, Hattori Toshiaki
doaj +1 more source
Engineered surface strategies to manage dental implant‐related infections
Periodontology 2000, EarlyView.Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Veterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas +4 more
wiley +1 more source
Benzophenone Derivatives as a New Class of Anti‐Infectives Against Acanthamoeba spp
Archiv der Pharmazie, Volume 359, Issue 8, August 2026.Analogues of the human oxidosqualene cyclase inhibitor Ro 48‐8071 were designed, synthesized, and tested against Acanthamoeba hatchetti, one of the pathogens causing Acanthamoeba keratitis. The N‐propargyl derivative 4f showed strong amoebicidal activity with complete eradication of trophozoites and cysts, while exhibiting low toxicity toward human ...
Tomas Rimkus +5 more
wiley +1 more source