Results 21 to 30 of about 4,114 (213)

Dual Crosslinked Ion-Based Bacterial Cellulose Composite Hydrogel Containing Polyhexamethylene Biguanide

Membranes, 2022
Composite bacterial cellulose (BC) based hydrogel with alginate (A) or pectin (P) or alginate and pectin was fabricated via a physical crosslinking technique using calcium chloride (CaCl2) solution and incorporated with polyhexamethylene biguanide (PHMB)
Baramee Chanabodeechalermrung, Tanpong Chaiwarit, Sarana Rose Sommano, Pornchai Rachtanapun, Nutthapong Kantrong, Chuda Chittasupho, Pensak Jantrawut   +6 more
doaj   +1 more source

Polyhexanide, Povidone-Iodine, and Hypochlorous Acid Show High In Vitro Antimicrobial Efficacy Against Pathogens Commonly Associated With Equine Infectious Keratitis. [PDF]

Vet Ophthalmol
ABSTRACT Objective To determine the in vitro antimicrobial activity of specific antiseptics against common equine ocular surface pathogens. Methods Staphylococcus aureus (S. aureus) (n = 12), Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) (n = 9), Enterobacter hormaechei (E. hormaechei) (n = 6), and Bacillus cereus (B.
Stolle LM, Oltmanns H, Meißner J, Heun F, Schieder AK, Wolff HT, Ohnesorge B, Busse C.   +7 more
europepmc   +2 more sources

Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus

JDS Communications, 2021
Postmilking teat disinfection is one of the main measures used to prevent mastitis caused by contagious pathogens, such as Staphylococcus aureus. The present study evaluated the antimicrobial activity of polyhexamethylene biguanide (PHMB) and PHMB ...
R.F. Leite, J.L. Gonçalves, A. Buanz, C. Febraro, D. Craig, S. Van Winden, L. Good, M.V. Santos   +7 more
doaj   +1 more source

Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus [PDF]

JAMA Ophthalmology, 2013
Swimming pools can be a vector for transmission of adenovirus ocular infections. Polyhexamethylene biguanide (PHMB) is a disinfectant used in swimming pools and hot tubs.To determine whether PHMB is an effective disinfectant against ocular adenovirus serotypes at a concentration used to disinfect swimming pools and hot tubs.In vitro laboratory study ...
Eric G, Romanowski, Kathleen A, Yates, Katherine E, O'Connor, Francis S, Mah, Robert M Q, Shanks, Regis P, Kowalski   +5 more
openaire   +2 more sources

Effect of combined therapy polyhexamethylene biguanide and Coriolus-MRL on human papilloma virus (HPV) cervical and vulvar-related lesions [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2020
OBJECTIVE: Human papillomavirus (HPV) persistent infections of genital tract are strongly related to the development of genital warts and cellular transformation.
D. Gincheva, V. Gincheva, E. Konova
doaj   +1 more source

Wound Healing Property of a Novel Thermo-Reversible Wound Gel With Lasting Antimicrobial and Antibiofilm Activity. [PDF]

Int Wound J
ABSTRACT This study investigated the efficacy and safety of a novel thermo‐reversible antimicrobial wound gel (TRG, revyve Antimicrobial Wound Gel) designed to combat biofilm‐related infections in wounds. The TRG was evaluated for its ability to disrupt biofilms, sustain antimicrobial activity and promote wound healing.
Visvalingam J, Li J, Jozic I, Lee SP, Sailer M, Gil J, Solis M, Davis SC, Huizinga RB.   +8 more
europepmc   +2 more sources

Polyvinyl Alcohol/Chitosan/Polyhexamethylene Biguanide Phase Separation System: A Potential Topical Antibacterial Formulation with Enhanced Antimicrobial Effect

Molecules, 2020
An aqueous polyvinyl alcohol (PVA)/chitosan (CHT)/polyhexamethylene biguanide (PHMB) blends (PVA/CHT/PHMB blends) has been developed as a potential low dose topical antibacterial formulation with enhanced antimicrobial effect.
Yunzhou Ni, Zhixiang Qian, Yu Yin, Weien Yuan, Fei Wu, Tuo Jin   +5 more
doaj   +1 more source

The Orphan Drug for Acanthamoeba Keratitis (ODAK) Trial: PHMB 0.08% (Polihexanide) and Placebo versus PHMB 0.02% and Propamidine 0.1. [PDF]

Ophthalmology, 2023
To compare topical PHMB (polihexanide) 0.02% (0.2 mg/ml)+ propamidine 0.1% (1 mg/ml) with PHMB 0.08% (0.8 mg/ml)+ placebo (PHMB 0.08%) for Acanthamoeba keratitis (AK) treatment.Prospective, randomized, double-masked, active-controlled, multicenter phase 3 study (ClinicalTrials.gov identifier, NCT03274895).One hundred thirty-five patients treated at 6 ...
Dart, John K.G., Papa, Vincenzo, Rama, Paolo, Knutsson, Karl Anders, Ahmad, Saj, Hau, Scott, Sanchez, Sara, Franch, Antonella, Birattari, Federica, Leon, Pia, Fasolo, Adriano, Kominek, Ewa Mrukwa, Jadczyk-Sorek, Katarzyna, Carley, Fiona, Hossain, Parwez, Minassian, Darwin C.   +15 more
openaire   +3 more sources

Stability of an ophthalmic formulation of polyhexamethylene biguanide in gamma-sterilized and ethylene oxide sterilized low density polyethylene multidose eyedroppers [PDF]

PeerJ, 2018
Background Polyhexamethylene biguanide (PHMB) eye drops are a frequently used medication to treat Acanthamoeba keratitis. In the absence of marketed PHMB eye drops, pharmacy-compounding units are needed to prepare this much needed treatment, but the lack
Yassine Bouattour, Philip Chennell, Mathieu Wasiak, Mireille Jouannet, Valérie Sautou   +4 more
doaj   +2 more sources

Safety assessment of Polyhexamethylene biguanide [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2019
OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù, P. Lista, M. Bertelli, V. Unfer   +3 more
doaj   +1 more source