Results 31 to 40 of about 1,778 (169)

Efficacy of surgical antiseptic handrub containing PHMB [PDF]

open access: yesBMC Proceedings, 2011
The efficacy and cytotoxicity of PHMB (polyhexamethylene biguanide) -containing surgical hand rub was investigated.
Noguchi E, Yamamoto M
openaire   +2 more sources

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

open access: yesParasite, 2021
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming   +7 more
doaj   +1 more source

Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis

open access: yesFrontiers in Microbiology, 2017
Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition to the problem of acquired drug resistance, bacterial invasion into udder
Nor F. Kamaruzzaman   +5 more
doaj   +1 more source

Antiseptic Chitosan-Poly(hexamethylene) Biguanide Hydrogel for the Treatment of Infectious Wounds

open access: yesJournal of Functional Biomaterials, 2023
Topical wound infections create the ideal conditions for microbial colonization and growth in terms of moisture, temperature, and nutrients. When they are not protected, numerous types of bacteria from the internal microbiota and the external environment
Irine Rose Antony   +5 more
doaj   +1 more source

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

open access: yesScientific Reports, 2016
AbstractTo combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells. Contrary to the accepted model of microbial membrane disruption by PHMB, we observed cell entry into a range ...
Chindera K   +10 more
openaire   +5 more sources

Safety of intrastromal injection of polyhexamethylene biguanide and propamidine isethionate in a rabbit model

open access: yesJournal of Advanced Research, 2020
Acanthamoeba keratitis (AK) is difficult to treat, especially when the corneal deep stroma is involved. Intrastromal injection of antimicrobial agents is an effective adjuvant therapy for deep recalcitrant microbial keratitis; however, it has not been ...
Chen-Chee Lim   +2 more
doaj   +1 more source

[Acanthamoeba keratitis treated with propamidine and polyhexamethyl biguanide (PHMB)].

open access: yesRevista medica de Chile, 2002
The diagnosis of acanthamoeba keratitis has increased since 1985 due to the massive use of contact lenses and a better knowledge of the disease by ophthalmologists. The use of biassociated therapy has resulted in a better prognosis and lower complication rate.To report patients with acanthamoeba keratitis treated with the association of propamidine ...
Rodrigo, Donoso   +2 more
openaire   +2 more sources

Effect of Local Administration of Meglumine Antimoniate and Polyhexamethylene Biguanide Alone or in Combination with a Toll-like Receptor 4 Agonist for the Treatment of Papular Dermatitis due to Leishmania infantum in Dogs

open access: yesPathogens, 2023
Papular dermatitis is a cutaneous manifestation of canine Leishmania infantum infection associated with mild disease. Although it is a typical presentation, nowadays, there is still no established treatment.
Icíar Martínez-Flórez   +10 more
doaj   +1 more source

Chlorhexidine 0.02% or polyhexamethylene biguanide 0.02% as the main treatment for Acanthamoeba keratitis

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To report medical cure and treatment failure rates of Acanthamoeba keratitis (AK) with respect to type of treatment, disease stage and prognostic factors. Methods Electronic records were reviewed for 45 patients with PCR‐positive AK treated at the Department of Ophthalmology, Aarhus University Hospital, Denmark from 2012 to 2025 ...
Anders Ivarsen   +5 more
wiley   +1 more source

Determination of polyhexamethylene biguanide hydrochloride

open access: yesReviews in Analytical Chemistry, 2014
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes.
Masadome Takashi, Hattori Toshiaki
doaj   +1 more source

Home - About - Disclaimer - Privacy