Results 31 to 40 of about 2,769 (189)

The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period of ...
Fu-Chin Huang, Tao-Shen Liu, Sung-Chou Li, Min-Hsiu Shih, Jyh-Wei Shin, Wei-Chen Lin   +5 more
doaj   +1 more source

In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa

Biomaterials Research, 2022
Aim Periprosthetic joint infections are a devastating complication after arthroplasty, leading to rejection of the prosthesis. The prevention of septic loosening may be possible by an antimicrobial coating of the implant surface.
Paula Zwicker, Thomas Schmidt, Melanie Hornschuh, Holger Lode, Axel Kramer, Gerald Müller   +5 more
doaj   +1 more source

Ecotoxicity of polyhexamethylene biguanide hydrochloride (PHMB) in the neotropical snail Biomphalaria glabrata (Say, 1818) [PDF]

Anais da Academia Brasileira de Ciências
The polyhexamethylene biguanide hydrochloride (PHMB) is a sanitizer with a broad range of potential applications. Nevertheless, the ecotoxicity of PHMB to gastropod snails remains scarce.
WALLACE N. DE JESUS, MARIA EDUARDA A. ALMEIDA, MARIA CLARA S. RAMOS, KARINE B. MACHADO, THIAGO L. ROCHA, LUCIANA DAMACENA-SILVA   +5 more
doaj   +2 more sources

Efficacy of surgical antiseptic handrub containing PHMB [PDF]

BMC Proceedings, 2011
The efficacy and cytotoxicity of PHMB (polyhexamethylene biguanide) -containing surgical hand rub was investigated.
Noguchi E, Yamamoto M
openaire   +2 more sources

Seed Coating with Biowaste Materials and Biocides—Environment-Friendly Biostimulation or Threat?

Agronomy, 2021
The presented study assessed the effect of bovine (BC) and fish (FC) waste-derived collagen, poly(hexamethylenebiguanide) hydrochloride (PHMB) and waste dolomite on the emergence of seedlings, growth and development of pea (Pisum sativum L.
Monika Skwarek, Mateusz Wala, Jeremi Kołodziejek, Katarzyna Sieczyńska, Magdalena Lasoń-Rydel, Katarzyna Ławińska, Andrzej Obraniak   +6 more
doaj   +1 more source

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

Parasite, 2021
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming, Ko Pin-Ju, Huang Chao-Li, Wen Po-Wei, Chen Chun-Hsien, Shih Min-Hsiu, Lin Wei-Chen, Huang Fu-Chin   +7 more
doaj   +1 more source

Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis

Frontiers in Microbiology, 2017
Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition to the problem of acquired drug resistance, bacterial invasion into udder
Nor F. Kamaruzzaman, Stacy Q. Y. Chong, Kamina M. Edmondson-Brown, Winnie Ntow-Boahene, Marjorie Bardiau, Liam Good   +5 more
doaj   +1 more source

In Vitro and In Vivo Comparison of a Novel Antimicrobial Wound Hydrogel With Commercial Wound Treatments: Antimicrobial, Antibiofilm and Biocompatibility Assessment. [PDF]

Int Wound J
ABSTRACT Antimicrobial resistance (AMR) and biofilm formation significantly hinder chronic wound management, necessitating safer and more effective therapeutic options. This study evaluates the antimicrobial, antibiofilm, cytocompatibility and anti‐inflammatory properties of a novel antimicrobial hydrogel Formulation (#1) compared with commercially ...
Moradi M, Pormohammad A, Luong C, Turner RJ.   +3 more
europepmc   +2 more sources

Antiseptic Chitosan-Poly(hexamethylene) Biguanide Hydrogel for the Treatment of Infectious Wounds

Journal of Functional Biomaterials, 2023
Topical wound infections create the ideal conditions for microbial colonization and growth in terms of moisture, temperature, and nutrients. When they are not protected, numerous types of bacteria from the internal microbiota and the external environment
Irine Rose Antony, Aathira Pradeep, Anoop Vasudevan Pillai, Riju Ramachandran Menon, Vasudevan Anil Kumar, Rangasamy Jayakumar   +5 more
doaj   +1 more source

PHMB/DNA interactions and physicochemical characterization of polyplexes.

, 2015
Formation of PHMB/DNA polyplexes confirmed by 1% agarose gel, TEM and color change. (a) PHMB/gDNA polyplexes, (b) TEM picture showing PHMB/CpG ODN polyplexes formation at 2:1 ratio, (c) PHMB/CpG ODN polyplexes, (d) temporary turbidity change during PHMB ...
Heidrun Moll (317342), Maria Cecilia Amstalden (802997), Liam Good (53703), Bianca Röger (634368), Nina Hecht (803001), Tobias A. Oelschlaeger (281562), Rebuma Firdessa (108932), Tessa Lühmann (803002), Lorenz Meinel (3509), Kantaraja Chindera (802998), Martina Schultheis (803000), Nor Fadhilah Kamaruzzaman (802999)   +11 more
core   +1 more source