Results 1 to 10 of about 2,203 (122)

Polyhexamethylene biguanide promotes adaptive cross-resistance to gentamicin in Escherichia coli biofilms [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
Antimicrobial resistance is a critical public health issue that requires a thorough understanding of the factors that influence the selection and spread of antibiotic-resistant bacteria.
Raphaël Charron, Raphaël Charron, Pierre Lemée, Antoine Huguet, Ornella Minlong, Marine Boulanger, Paméla Houée, Christophe Soumet, Romain Briandet, Arnaud Bridier   +9 more
doaj   +2 more sources

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment [PDF]

Parasite, 2021
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming, Ko Pin-Ju, Huang Chao-Li, Wen Po-Wei, Chen Chun-Hsien, Shih Min-Hsiu, Lin Wei-Chen, Huang Fu-Chin   +7 more
doaj   +2 more sources

Efficacy of 0.2% povidone-iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures. [PDF]

Vet Ophthalmol
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Farkas A, Thieme K, Soimala T, Jensen CK, Eule JC.   +4 more
europepmc   +2 more sources

Dual Crosslinked Ion-Based Bacterial Cellulose Composite Hydrogel Containing Polyhexamethylene Biguanide [PDF]

Membranes, 2022
Composite bacterial cellulose (BC) based hydrogel with alginate (A) or pectin (P) or alginate and pectin was fabricated via a physical crosslinking technique using calcium chloride (CaCl2) solution and incorporated with polyhexamethylene biguanide (PHMB)
Baramee Chanabodeechalermrung, Tanpong Chaiwarit, Sarana Rose Sommano, Pornchai Rachtanapun, Nutthapong Kantrong, Chuda Chittasupho, Pensak Jantrawut   +6 more
doaj   +2 more sources

Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus [PDF]

JDS Communications, 2021
Postmilking teat disinfection is one of the main measures used to prevent mastitis caused by contagious pathogens, such as Staphylococcus aureus. The present study evaluated the antimicrobial activity of polyhexamethylene biguanide (PHMB) and PHMB ...
R.F. Leite, J.L. Gonçalves, A. Buanz, C. Febraro, D. Craig, S. Van Winden, L. Good, M.V. Santos   +7 more
doaj   +2 more sources

Fungal cell barriers and organelles are disrupted by polyhexamethylene biguanide (PHMB) [PDF]

Scientific Reports, 2023
The similarities between fungal and mammalian cells pose inherent challenges for the development of treatments for fungal infections, due to drug crossover recognition of host drug targets by antifungal agents.
Winnie Ntow-Boahene, Isabelle Papandronicou, Josephous Miculob, Liam Good   +3 more
doaj   +2 more sources

Polyhexamethylene Biguanide Nanoparticles Inhibit Biofilm Formation by Mastitis-Causing Staphylococcus aureus [PDF]

Veterinary Sciences
Staphylococcus aureus is a mastitis pathogen that compromises cow health and causes significant economic losses in the dairy industry. High antimicrobial resistance and biofilm formation by S. aureus limit the efficacy of conventional treatments.
Renata de Freitas Leite, Breno Luis Nery Garcia, Kristian da Silva Barbosa, Thatiane Mendes Mitsunaga, Carlos Eduardo Fidelis, Bruna Juliana Moreira Dias, Renata Rank de Miranda, Valtencir Zucolotto, Liam Good, Marcos Veiga dos Santos   +9 more
doaj   +2 more sources

Safety of intrastromal injection of polyhexamethylene biguanide and propamidine isethionate in a rabbit model [PDF]

Journal of Advanced Research, 2020
Acanthamoeba keratitis (AK) is difficult to treat, especially when the corneal deep stroma is involved. Intrastromal injection of antimicrobial agents is an effective adjuvant therapy for deep recalcitrant microbial keratitis; however, it has not been ...
Chen-Chee Lim, I-Chen Peng, Yi-Hsun Huang   +2 more
doaj   +2 more sources

The dltC gene contributes to polyhexamethylene biguanide resistance in Staphylococcus aureus [PDF]

Frontiers in Microbiology
As the efficacy of conventional antibiotics continues to decline due to antibiotic resistance, there is an urgent need for alternative antimicrobial strategies.
Chenyang Guo, Congcong Wang, Qihui Chen, Sophia Hao Zheng, Fengji Zhang, Jiayu Yan, Haoyang Brady Long, Jing Luo, Xiaoyan Xuan, Peng Wang, Huaixin Zheng   +10 more
doaj   +2 more sources

Management of Severe Pediatric Lower Lip Defect After Canine Bite with Polyhexamethylene Biguanide (PHMB), Full-Thickness Skin Graft (FTSG) and Compression Foam: A Case Report [PDF]

Children
Introduction: Pediatric lower-lip dog bite injuries are challenging due to contamination, tissue loss, and the need to maintain function, appearance, and psychological well-being.
Aba Lőrincz, Hermann Nudelman, Anna Gabriella Lamberti, Attila Vástyán, Enikő Molnár, Gábor Pavlovics, Gergő Józsa   +6 more
doaj   +2 more sources