Contact allergy to polyhexamethylene biguanide (polyaminopropyl biguanide). [PDF]
Contact Dermatitis, 2021 AbstractBackgroundPolyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad‐spectrum antimicrobial substance used as a preservative in many products. Due to our limited knowledge on PHMB contact allergy frequency and the fact that cases of allergic contact dermatitis to PHMB might be missed ...
Sukakul T +9 more
europepmc +9 more sources
Fungal cell barriers and organelles are disrupted by polyhexamethylene biguanide (PHMB) [PDF]
Scientific Reports, 2023 The similarities between fungal and mammalian cells pose inherent challenges for the development of treatments for fungal infections, due to drug crossover recognition of host drug targets by antifungal agents.
Winnie Ntow-Boahene +3 more
doaj +6 more sources
Safety of intrastromal injection of polyhexamethylene biguanide and propamidine isethionate in a rabbit model [PDF]
Journal of Advanced Research, 2020 Acanthamoeba keratitis (AK) is difficult to treat, especially when the corneal deep stroma is involved. Intrastromal injection of antimicrobial agents is an effective adjuvant therapy for deep recalcitrant microbial keratitis; however, it has not been ...
Chen-Chee Lim +2 more
doaj +5 more sources
Determination of polyhexamethylene biguanide hydrochloride [PDF]
Reviews in Analytical Chemistry, 2014 Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes.
Masadome Takashi, Hattori Toshiaki
doaj +3 more sources
Polyhexamethylene biguanide promotes adaptive cross-resistance to gentamicin in Escherichia coli biofilms [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 Antimicrobial resistance is a critical public health issue that requires a thorough understanding of the factors that influence the selection and spread of antibiotic-resistant bacteria.
Raphaël Charron +9 more
doaj +6 more sources
Dual Crosslinked Ion-Based Bacterial Cellulose Composite Hydrogel Containing Polyhexamethylene Biguanide [PDF]
Membranes, 2022 Composite bacterial cellulose (BC) based hydrogel with alginate (A) or pectin (P) or alginate and pectin was fabricated via a physical crosslinking technique using calcium chloride (CaCl2) solution and incorporated with polyhexamethylene biguanide (PHMB)
Baramee Chanabodeechalermrung +6 more
doaj +4 more sources
Use of Native Type I Collagen Matrix Plus Polyhexamethylene Biguanide for Chronic Wound Treatment [PDF]
Plastic and Reconstructive Surgery, Global Open, 2019 Background:. Chronic wounds represent a significant financial burden to the healthcare system and a quality-of-life burden to patients. Many chronic wounds have elevated bioburden in the form of biofilm, which has been associated with delayed wound ...
Alisha R. Oropallo, MD, FACS
doaj +3 more sources
Safety assessment of Polyhexamethylene biguanide [PDF]
International Journal of Medical Device and Adjuvant Treatments, 2019 OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù +3 more
doaj +2 more sources
Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment [PDF]
Parasite, 2021 Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming +7 more
doaj +2 more sources
Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus [PDF]
JDS Communications, 2021 Postmilking teat disinfection is one of the main measures used to prevent mastitis caused by contagious pathogens, such as Staphylococcus aureus. The present study evaluated the antimicrobial activity of polyhexamethylene biguanide (PHMB) and PHMB ...
R.F. Leite +7 more
doaj +2 more sources