Results 41 to 50 of about 4,089 (226)

Polyhexanide as a new antiseptic composition for a dentist

Эндодонтия Today, 2021
Aim. To assess systematically the available scientific evidence about clinical response of using polyhexanide as an antiseptic agent in medicine and dentistry.
Z. S. Khabadze, D. S. Nazarova, A. A. Kulikova, Yu. A. Generalova, E. S. Shilyaeva, A. P. Kotelnikova   +5 more
doaj   +1 more source

Polyhexamethylene biguanide exposure leads to viral aggregation [PDF]

Journal of Applied Microbiology, 2009
This study reports the activity of two biguanides against MS2 bacteriophage used as a surrogate virus for nonenveloped mammalian viruses and provides an explanation as to their apparent limited efficacy.When tested in a standard suspension test, two polyhexamethylene biguanides (PHMB), VANTOCIL TG and COSMOCIL CQ, reduced the viability of MS2 by only 1-
Pinto, Federica, Maillard, J.-Y., Denyer, Stephen, McGeechan, P.   +3 more
openaire   +2 more sources

Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review

Membranes, 2022
The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj   +1 more source

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources

Microsporidial stromal keratitis in an immunocompromised patient: Successful management with medical therapy

Indian Journal of Ophthalmology, 2020
Microsporidial stromal keratitis is refractory to topical drugs and is classically described in immunocompetent hosts. A 55-year-old patient with renal transplant and oral immunosuppressants, presented with a 15-day history of redness, pain, and ...
Amanjot Kaur, Srikant K Sahu, Sanchita Mitra, Sujata Das   +3 more
doaj   +1 more source

Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]

, 2016
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core   +1 more source

Loss of Function in Escherichia coli exposed to Environmentally Relevant Concentrations of Benzalkonium Chloride [PDF]

, 2018
Assessing the risk of resistance associated with biocide exposure commonly involves exposing microorganisms to biocides at concentrations close to the MIC. With the aim of representing exposure to environmental biocide residues, MG1655 was grown for 20
Bloomfield SF, Chuanchuen R, European Committee for Antimicrobial Susceptibility Testing of the European Society of Clinical Microbiology and Infectious Diseases, Gilbert P, Girón JA, Grillitsch B, Heir E, Klimek JW, Kümmerer K, Langsrud S, Maki DG, Nagai K   +11 more
core   +8 more sources

Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2013
Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene
Genevieve Walls, Lisa Noonan, Elizabeth Wilson, David Holland, Simon Briggs   +4 more
doaj   +1 more source

Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics [PDF]

, 2013
A flexible methacrylate powder dressing (Altrazeal®) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics.
Archibald, Assadian, Axel Kramer, Beldon, Braga, Chen, Christina Forstner, Clark, Cutting, David Leaper, Deitch, Disemond, Eberlein, Fang, Fitzgerald, Henry-Stanley, Hirsch, Johannes Leitgeb, Keith Cutting, Kim, Lalani, Leaper, Leaper, Migliaresi, Minnich, Nathan, Nordmann, Ojan Assadian, Rupert Schuster, Sibbald, Tsou, Vanscheidt, Verena Dosch, Wang, Winter   +34 more
core   +4 more sources

ANTIBACTERIAL ACTIVITY AND QUANTIFICATION OF POLYHEXAMETHTYLENE BIGUANIDE HYDROCHLORIDE IN MUSCULAR TISSUES AND VISCERA OF BROILERS ATIVIDADE ANTIBACTERIANA E QUANTIFICAÇÃO DE CLORIDRATO DE POLIHEXAMETILENO BIGUANIDA (P.H.M.B.) EM TECIDOS MUSCULARES E VÍCERAS DE FRANGOS

Pesquisa Agropecuária Tropical, 2007
<!-- @page { margin: 2cm } --> <p class="western" align="justify">Trials were carried out in order to check the viability of polyhexamethylene biguanide hydrochloride in the control of pathogenic and degenerating bacteria in carcass of ...
Albenones José de Mesquita, Moacir Evandro Lage, Guilherme Roberto de Oliveira, Cristiano Sales Prado   +3 more
doaj   +1 more source