Results 51 to 60 of about 2,253 (158)

The High Impact of Staphylococcus aureus Biofilm Culture Medium on In Vitro Outcomes of Antimicrobial Activity of Wound Antiseptics and Antibiotic

Pathogens, 2021
The staphylococcal biofilm-based infections of wounds still pose a significant therapeutical challenge. Treated improperly, they increase the risk of limb amputation or even death of the patient. The present algorithms of infected wound treatment include,
Justyna Paleczny, Adam Junka, Malwina Brożyna, Karolina Dydak, Monika Oleksy-Wawrzyniak, Daria Ciecholewska-Juśko, Ewelina Dziedzic, Marzenna Bartoszewicz   +7 more
doaj   +1 more source

In Vitro and In Vivo Comparison of a Novel Antimicrobial Wound Hydrogel With Commercial Wound Treatments: Antimicrobial, Antibiofilm and Biocompatibility Assessment

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Antimicrobial resistance (AMR) and biofilm formation significantly hinder chronic wound management, necessitating safer and more effective therapeutic options. This study evaluates the antimicrobial, antibiofilm, cytocompatibility and anti‐inflammatory properties of a novel antimicrobial hydrogel Formulation (#1) compared with commercially ...
Melika Moradi, Ali Pormohammad, Charline Luong, Raymond J. Turner   +3 more
wiley   +1 more source

Implementing Wound Hygiene in the Italian Healthcare Context: Expert Recommendations for the Management of Venous Leg Ulcers

International Wound Journal, Volume 23, Issue 3, March 2026.
ABSTRACT The ‘Wound Hygiene Italia’ project was designed to provide expert‐driven recommendations for the assessment, management and monitoring of venous leg ulcers, tailored to diverse settings of care (hospital, ambulatory and home care). The recommendations, developed by a multidisciplinary panel, emphasise the implementation of the Wound Hygiene ...
Alessandro Scalise, Franco Bassetto, Diego Ceci, Guido Ciprandi, Deborah Cesura Granara, Barbara De Angelis, Ciro Falasconi, Domitilla Foghetti, Francesco Giacinto, Alessandro Greco, Filippo Magnoni, Marco Marchelli, Giuseppe Nebbioso, Battistino Paggi, Giovanni Papa, Francesco Petrella, Salvatore Piazza, Marco Romanelli, Elia Ricci, Sara Sandroni   +19 more
wiley   +1 more source

The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period of ...
Fu-Chin Huang, Tao-Shen Liu, Sung-Chou Li, Min-Hsiu Shih, Jyh-Wei Shin, Wei-Chen Lin   +5 more
doaj   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

Acta Ophthalmologica, Volume 104, Issue 1, Page 44-51, February 2026.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Anders Ivarsen   +5 more
wiley   +1 more source

The Effect of Polyhexamethylen Biguanide on Microorganisms in Root Canal

Acta Stomatologica Croatica, 2013
The objective of this study was to test the effectiveness of 0.2% polyhexamethylen biguanide in the elimination of Enterococcus faecalis, Pseudomonas aeruginosa and Candida albicans and compare it with effectiveness of 2.5% sodium hypochlorite.
Medvedec Mikić, Ivana, Prpić-Mehičić, Goranka, Matijević, Jurica, Simeon, Paris, Tadin, Antonija, Tambić Andrašević, Arjana   +5 more
openaire   +3 more sources

Pantoea agglomerans in Equine Ulcerative Keratitis: Prevalence and Comparative Efficacy of Four Topical Antiseptics

Veterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT Objective To determine the minimal bactericidal concentration (MBC) and effective contact time of four topical antiseptics—polyhexanide, povidone‐iodine (PVP‐I), hypochlorous acid (HOCl), and N‐acetylcysteine (NAC)—against Pantoea agglomerans, a pathogen frequently isolated in equine ulcerative keratitis.
Frederik Heun, Jessica Meißner, Ann‐Kathrin Schieder, Bernhard Ohnesorge, Claudia Busse   +4 more
wiley   +1 more source

18S rDNA sequencing aided diagnosis of Acanthamoeba jacobsi keratitis -A case report

Indian Journal of Ophthalmology, 2019
Identification of Acanthamoeba cysts and trophozoites in cases of keratitis is traditionally done with microbiological techniques such as smear examination with 10% potassium hydroxide (KOH) and culture.
Aastha Singh, Manisha Acharya, Nicy Jose, Arpan Gandhi, Savitri Sharma   +4 more
doaj   +1 more source

Organic Polyurethane Surface Structures to Manufacture Noneluting Antimicrobial Polyurethanes: A Systematic Review of Literature

BioMed Research International, Volume 2026, Issue 1, 2026.
The dramatic increase in hospital‐acquired infections and healthcare costs associated with infection treatment and antimicrobial resistance in implant infections necessitates further research and development of antimicrobial implant material properties. Polyurethanes are key biomaterials used in medical implants and devices.
Bianca J. Hurck, Marian G. Vargas Guerrero, Candice de Boer, Aylvin A. Dias, Jacobus J. C. Arts, Seyed Shahmy   +5 more
wiley   +1 more source